Open Access DOI:10.23937/2469-5769/1510124

Asparaginase-Associated Necrotizing Pancreatitis Successfully Treated with Octreotide: A Case Report and Review of the Literature

Giulia Angela Restivo, MD, Angela Guarina, MD, Barbara Torrente, MD, Sara Genuardi, MD, Piero Farruggia, MD and Paolo D'Angelo, MD

Article Type: Case Report | Publication Updated: 2024/02/15

Pancreatitis is a common adverse reaction to asparaginase and a reason for drug discontinuation in patients with acute lymphoblastic leukemia. Diagnostic criteria include elevated pancreatic enzymes, abdominal symptoms and/or imaging findings suggestive of pancreatitis. There is no specific treatment, but in a few reports, octreotide seems to be an effective drug in reducing acute complications and mortality. Here we describe the case of a child who developed asparaginase-induced necrotizing pan...

 Open Access DOI:10.23937/2643-4474/1710155

Rare Galen Vein Aneurysm in a 40-Year-Old Woman: In-Depth Analysis of an Exceptional Case

Dantas Mageste Ferreira, MD, MSc, Vitor de Deus da Rocha Ribeiro Gonçalves, MD, Lano de Sousa Moreira, MD, Taianne Fiore Schumann, MD and Jéssica Aguilar da Silva

Article Type: Case Report | Publication Updated: 2024/02/09

Vein of Galen aneurysm is a rare vascular condition commonly diagnosed in children. This type of aneurysm arises from the persistence of the embryonic median prosencephalic vein, precursor to the Galen vein. This paper highlights the rarity of this phenomenon in a 40-year-old woman. The aim of this study is to demonstrate that conservative treatment of this malformation can be a valid option in oligosymptomatic cases without signs of hydrocephalus....

 Open Access DOI:10.23937/2474-3658/1510315

Seropositivity of Anti-CMV IgM Antibody among Women of Child-Bearing Age Attending Selected Hospitals in Kaduna State, Nigeria

Anchau Zainab Garba, Suleiman Ahmad Babangida, Olonitola O Stephen and Kwanashie Clara N

Article Type: Original Article | Publication Updated: 2024/02/11

Human Cytomegalovirus is one of the most common cause of congenital viral infections. The study was conducted to determine the seroprevalence of Human Cytomegalovirus among women of child-bearing age attending selected hospitals in Kaduna State, Nigeria. A total of 228 blood samples were obtained from the women and processed serologically using Enzyme Linked Immunosorbent Assay (ELISA). In addition, structured questionnaire was used to determine socio-demographic and risk factors associated with...

 Open Access DOI:10.23937/2474-3682/1510232

Posterior Segment Flail Chest: A Radiological Diagnosis

Yudhyavir Singh, Baby Pegu and Kapil Dev Soni

Article Type: Clinical Image | Publication Updated: 2024/02/12

A 35-year-old male reported to the emergency department after a road traffic accident with complaints of chest pain on the left side and breathing difficulty. On the primary survey, his GCS was full, his airway was patent, breathing spontaneously with a respiratory rate of 28/min with paradoxical movement on the left of the chest, heart rate of 102/min, and blood pressure of 116/78 mmHg. On further evaluation, the chest compression test was positive on the left side, but FAST and eFAST scan were...

 Open Access DOI:10.23937/2469-5750/1510123

Paraneoplastic Pemphigus Pemphigoid Like

Edgar Bedang Mone Keby da Costa, El khalil El Bakali, Hasna Kerrouche, Mohamed Amine Essaudi, Youssef Zemmez, Rachid Frikh and Naoufal Hjira

Article Type: Case Report | Publication Updated: 2024/02/11

Paraneoplastic pemphigus is a very rare disease. However, it has been described in many countries. It most often affects middle-aged adults, but a few pediatric cases have also been reported. We report the clinical case of a patient being followed for colon cancer who developed erythematous plaques topped by clear and hemorrhagic bullae. Our patient was undergoing treatment with oral corticosteroids and chemotherapy. Paraneoplastic pemphigus was first described in 1990. Since then, numerous case...

 Open Access DOI:10.23937/2469-5769/1510123

Physical Activity Levels of Children and Young People in an Inpatient Setting: A Systematic Review

Kieren James Lock, Colin Hamilton and David Young

Article Type: Review Article | Publication Updated: 2024/02/10

CYP with physical health conditions had significantly lower PA levels than recommendations during inpatient admissions. In contrast, individuals with Anorexia Nervosa (AN) met WHO guidelines for Moderate to Vigorous PA. Fidgeting was observed to be higher in admitted AN patients compared to community, suggesting a potential compensatory mechanism for reduced step count. Notably, hospitalisation itself resulted in a decline in PA levels....

 Open Access DOI:10.23937/2474-3674/1510159

A Rare Cause of Acute Chest Pain

Cátia Ribeiro Santos, Carolina Roriz and Vera Frazão Vieira

Article Type: Patient Care | Publication Updated: 2024/02/09

Chest pain is one of the most common symptoms for which adults seek medical care, making chest pain the second most common complaint [1]. A central goal in the emergency department is to determine whether acute chest pain is a life-threatening condition for the patient [1,2]. Acute onset of chest may also be seen with disorders such as aortic aneurysm dissection, myocardial infarction, spontaneous pneumothorax, pneumonia, pancreatitis, peptic ulcer perforation, or esophageal perforation....

 Open Access DOI:10.23937/2469-5823/1510195

Disclosure Status and Associated Factors among Caregivers of Children on Antiretroviral Therapy in Addis Abeba, Ethiopia: Hospital Based Cross Sectional Study Design

Yoseph Wondmneh, BSc, MPH/RH and Dereje Bayissa Demissie, BSc, MSc/MRH, PhD

Article Type: Original Research | Publication Updated: 2024/02/15

A hospital based cross sectional study design was conducted at government hospital under A.A city administration from Nov to Feb 2021. Systematic random sampling technique was used to select, care giver/parents. Data was collected by interview using pre-test structured questionnaires. Descriptive statistics were used to illustrate the means, standard deviations, and frequencies of the study variables. Bivariate logistic regression was performed and those variables whose p-values less than or equ...

 Open Access DOI:10.23937/2469-5866/1410047

How Necessary is Duraplasty in the Treatment of Chiari Malformation?

Mahmut CAMLAR, Mustafa Eren YUNCU, Ali KARADAG, Merve OREN, Caglar TURK, Ozgur OZTEKİN and Fusun OZER

Article Type: Original Research | Publication Updated: 2024/02/08

In this study, 46 patients who were operated on for Type I Chiari malformation (CM) in our clinic since 2010 were included. The preoperative and postoperative cranial and spinal MRI examinations of all patients were compared between the two groups in terms of hydrocephalus, tonsillar herniation level, the presence and level of syringomyelia, osseous anomalies, postoperative cisterna magna formation, postoperative obex structure, and syringomyelia status....

 Open Access DOI:10.23937/2469-5823/1510194

Prevalence and Associated Factors of Postpartum Depression among Postpartum Women in Mahatma Gandhi Memorial Hospital of Addis Ababa, Ethiopia: An Institutional Based Cross-Sectional Study

Nardos Tesfahun and Dereje Bayissa Demissie

Article Type: Original Research | Publication Updated: 2024/02/07

Postpartum depression (PPD) is a universal mental illness that explains various groups of depressive symptoms and syndromes that occur during the first year after birth. Untreated postpartum depression has serious long-term adverse effects on both the mothers and their children. Despite its massive effects, particularly in low- and lower-income countries, women and clinicians do not adequately understand it....