Open Access DOI:10.23937/2378-3419/1410118
Frailty as a Prognosis Factor in Cancer for the Elderly
Miguel Angel Acosta-Benito, Rosa Ana Garcia-Pliego, Jaime Barrio-Cortes and Veronica Rodriguez-FernAndez
Article Type: Research Article | First Published: June 20, 2019
Frailty is a geriatric syndrome related to adverse health outcomes in the elderly, due to a decrease systems' functional reserve. Cancer is a common pathology in the elderly, and we need tools for identifying the response to treatment and prognosis of elderly cancer patients. This short revision aims to assess the significance of the detection of frailty in the elderly patient with a tumor as a possible prognostic factor in terms of mortality, and the impact of the 2013 Frailty Consensus in the ...
Open Access DOI:10.23937/2378-3419/1410117
Current Recommendations of Radioactive Seed ~ (125)I Implantation in Lung Brachytherapy: Moving Forward in Medical Care
Wang Yuchan, Yuan Gengbiao, Lee Changyi, Ran Lifeng and Yang Wei
Article Type: Review Article | First Published: June 20, 2019
Isotopes of radioactive iodine have a persistent lethal effect on the uncontrolled proliferation of tumor cells with a definite curative effect on tumors. It has been proved, up to 87.2% of 3-year's survival rate that could be achieved by radioactive seeds. Iodine-125 radioactive seeds have a long half life and low energy with excellent stable outcomes. Various effective isotopes with advanced techniques are used to place radioactive sources directly into a tumor, tumor bed in treating lung canc...
Open Access DOI:10.23937/2378-3419/1410116
Breast Cancer Survivors: Is Routine 'Mammographic Only' follow up Imaging Enough or is it Time for Personalised follow up?
Gaurav Jyoti Bansal, Thomas Telford and Kevin Pinto
Article Type: Original Article | First Published: June 20, 2019
Breast cancer is the most common cancer in women, accounting for approximately 15% of all cancers. Over 85% of these people survive beyond 5 years after diagnosis, due to continual progressions in early detection and treatment quality. Despite advances in detection and treatment, 20-30% of patients develop local relapse or distant metastasis. Molecular subtyping of breast cancers based on receptor expression has been introduced in clinical practice and has developed into an important tool in pre...
Open Access DOI:10.23937/2378-3419/1410115
Breast Fibromatosis: Case Report, Case Series, and Mini Review
Alicia Huff Vinyard, DO, Rachel Berger, MS-IV, TolgaOzmen, MD and Eli Avisar, MD
Article Type: Case Report | First Published: June 15, 2019
Fibromatosis of the breast is a rare, benign tumor, lacking metastatic potential, but can be aggressive and create issues with loco-regional control if not adequately treated. In the literature, fibromatosis of the breast is often discussed only in case reports and small case series. The consensus on treatment remains wide local excision, however, other therapies have been described. In discussion of an interesting case presentation of what we have defined as secondary breast fibromatosis, we re...
Open Access DOI:10.23937/2474-3674/1510081
Iatrogenic Related to the Knowledge Deficit of Patient Safety in the Care: A Descriptive Analysis
Eliza Miranda Ramos, Matheus Dullius Lima, Valter Aragao do nascimento, Ph.D and Elaine Cristina Fernandes Baez Sarti
Article Type: Research Article | First Published: June 22, 2019
Iatrogenic conditions are those that result from the intervention of the multidisciplinary health team, whether correct or incorrect, justified or not, but which result in detrimental consequences for the patient's health. Few studies have focused on assessing the risks to patients, especially those hospitalized in emergency and intensive care services, and only in the last decades attention has been drawn to the importance of these problems...
Open Access DOI:10.23937/2469-5696/1410040
ABO Blood Group: Its Relationship with Anthropometric Parameters Among Young Adult Nigerians of Yoruba Ethnicity
Asafa MA, Ogunlade O, Bolarinwa RA, Bisiriyu LA and Asafa ST
Article Type: Research Article | First Published: June 17, 2019
It had been established that ABO blood group system associated with some diseases or disorders. The objective of this study was to determine the effect of ABO blood group on anthropometric indices among apparently healthy young adults of Yoruba ethnicity. Eighty apparently healthy young adults who were purposely selected participated in the study after screening for the ABO blood groups following the standard protocol. They were divided into four equal groups; 20 in each of blood groups A, B, AB...
Open Access DOI:10.23937/2469-5866/1410029
The Role of Prolyl Oligopeptidase in Microtubule-Associated Processes and Cognitive Impairment
Nuria Trallero, Ariadna Anunciacion-Llunell, Roger Prades and Teresa Tarrago
Article Type: Review Article | First Published: June 29, 2019
Prolyl oligopeptidase (POP) is a cytosolic serine protease with prominent expression in the brain. Inhibition of this enzyme leads to cognition-enhancing and neuroprotective effects in animal models with cognitive deficits. However, the biological function of POP remains unknown. Although in the past it was though that its catalytic activity was responsible for its physiological role, lately it has been hypothesized that POP is involved in the inositol pathway and that it interacts with several ...
Open Access DOI:10.23937/2643-4512/1710023
Out of a Silo, Into Everyday Healthcare: Nutrition Inclusion in Medicine
Julie Babyar, RN MPH
Article Type: Narrative Review | First Published: June 12, 2019
Nutrition science is currently viewed as part of healthcare, in a separate silo Nutrition science is currently not fully integrated into medicine. Food safety, malnutrition, access and quality issues, chronic conditions and obesity are all components of nutritional health, nutritional health is not viewed as a specialty partner with everyday presence. Additionally, research on nutrition is unorganized and lacking....
Open Access DOI:10.23937/2643-4016/1710011
A Dedicated Orthopaedic Trauma Admission Document Significantly Improves Recording of Patient Information
Jefferies JG, Brown CD and Shields D
Article Type: Original Article | First Published: June 24, 2019
Meticulous documentation in clinical records has been shown to improve patient care and clinician performance. Conversely, poor documentation is associated with an increased risk of adverse events. The Royal College of Surgeons (RCS) issues guidance on the contents of surgical admissions documentation. Audit highlighted frequent omission of key criteria set out by RCS with freehand documentation. We set out to design, implement, and evaluate an orthopaedic admission proforma for our trauma patie...