Open Access DOI:10.23937/2643-4474/1710040
Reconstruction of Cranial Defect With Individualized PEEK Implant: Case Report
Cristopher Mayer O, Tomás Donoso H, Roberto García B, Claudio Huentequeo M and Francisco Pampin L
Article Type: Case Report | First Published: August 12, 2020
Cranioplasty has numerous indications, and its main objective is to support the underlying noble structures, along with restoring shape and aesthetics. The treatment of choice is controversial, and is mainly related to the type of material to be used. There were no complications in the perioperative period, nor were there rejection reactions, infection or exposure of the implant in the postoperative period, with satisfactory aesthetic (improvement of the cranial contour) and functional results d...
Open Access DOI:10.23937/2469-5726/1510084
Comparison between Different Disease Activity Scores in Black African Patients with Rheumatoid Arthritis: A Cross-Sectional Multicenter Study
Marie Traoré, Alhassane Diallo, Aly Badra Kamissoko, Paul Eloundou, MD, Mamadou Lamine Diallo and Thierno Amadou Wann
Article Type: Original Article | First Published: August 12, 2020
Although the discordance in the disease activity scores based on 28 joints (DAS28) has been widely investigated, few data exist among black African (BA) populations. We aimed first to evaluate the correlation and second to assess the concordance between various DAS28 scores in the BA patients with rheumatoid arthritis (RA). We conducted a multicenter cross-sectional study in adult patients who had RA from Guinea and Cameroon. These patients were diagnosed according to the 2010 ACR/EULAR criteria...
Open Access DOI:10.23937/2474-3658/1510152
Investigation on the Sub-Health Status of Healthcare Workers during the COVID-19 Pandemic
Miao-hang Shan, Yan-bin Pan, Wan-xian Lu, Jin-ling Wu, Wen-ying Li and Dong-yu Zeng
Article Type: Original Article | First Published: August 07, 2020
Coronavirus Disease 2019 (COVID-19) is a viral pneumonia caused by novel coronavirus infection, showing a general susceptibility pattern and extremely high infectivity. It is currently a public health emergency of international concern. As the direct staff to deal with and control the pandemic situation, healthcare workers may experience physical, psychological, and social stresses at different levels. Therefore, it is necessary to investigate the sub-health status of healthcare workers to provi...
Open Access DOI:10.23937/2474-3658/1510151
Efficacy and Safety Data of Treatments for Novel Coronavirus Pneumonia (SARS-Cov-2): A Systematic Review and Network Meta-Analysis of Randomized Trials
Alhassane Diallo, MD, PhD, Marie Traoré, MD, Miguel Carlos-Bolumbu, MD, Mamadou Hassimiou Diallo, MSc and Boubacar Djelo Diallo, MD
Article Type: Systematic Review | First Published: August 06, 2020
To date, there is no definite effective treatment for the novel coronavirus (SARS-CoV-2) pandemic. To compare and rank SARS-Cov-2 treatment according to their efficacy and safety. Using the terms Covid-19 or SARS-CoV-2 and treatment, a literature search was performed from MEDLINE, GOOGLE, and CENTRAL databases until July 01, 2020. Randomized clinical trials (RCTs) against SARS-CoV-2 disease were included. The studies excluded were those with nonrandomized design or those with a lack of informati...
Open Access DOI:10.23937/2474-3690/1510049
Burden of Chronic Kidney Disease in Hypertensive Patients in Medical Outpatient Clinic of a Rural Tertiary Hospital
Olarinde Jeffrey Oluwademilade, Gbadebo Oladimeji Ajani, Fasanmi Tolulope Kolawole, Omotola Olawale Obajolowo, Eunice Oluremi Olabinri and Segun Matthew Agboola
Article Type: Original Article | First Published: August 14, 2020
There is an alarming rise of chronic kidney disease (CKD) prevalence globally, which is associated with significant morbidity and mortality necessitating special attention as a major public health problem. Data on the burden of CKD on the African continent are sparse for rural population. Hypertension related kidney disease accounts for a large percentage of the population requiring renal replacement therapy worldwide. Therefore, we determined the burden of CKD in patients with hypertension atte...
Open Access DOI:10.23937/2474-3690/1510048
Medication Adherence: Assess Compliance and Associated Factors among Hypertensive Patients
Yashawant Ramawat, Nitesh Kumawat, Shatrughan Pareek, Vijay Kumar and Ankur Sharma
Article Type: Original Article | First Published: August 10, 2020
Health care decision-makers require more information on differences in compliance rates associated with antihypertensive drugs and the implications of these differences for health care utilization and costs. This community- based prospective study was conducted to assess hypertensive patients’ compliance with their prescribed regimen. This was a cross-sectional community-based prospective study. Four hundred hypertensive patients were selected from OPD of tertiary care centre hospital of Delhi...
Open Access DOI:10.23937/2469-5858/1510096
COVID-19 and Hospital-Acquired Delirium
Pooja Nair, Aileen Nguyen, Nishita Nigam and Abraham Kanal
Article Type: Perspective Piece | First Published: August 20, 2020
Delirium is a frequently encountered condition in hospital medicine and can be associated with extended hospitalizations as well as higher rates of morbidity and mortality, with significant impact on the elderly population. The COVID-19 pandemic is expected to increase the burden of delirium amongst hospitalized patients. Thus far, evidence-based interventions that have been shown to be effective in preventing and reducing the morbidity associated with this condition include early screening and ...
Open Access DOI:10.23937/2378-3648/1410050
SARS-CoV-2 Global Spreading Investigation Using Principal Component Analysis of Sequence Variants
Christiane Scherer, James Grover, Darby Kammeraad, Gabe Rudy and Andreas Scherer
Article Type: Research Article | First Published: August 13, 2020
As COVID-19 has spread from its origin in Wuhan, China, into a global pandemic, there has been a number of efforts to understand the mutations and clusters of genetic lineages of the SARS-CoV-2 virus. The high mutation rate and rapid spread makes this analysis capable of tracking chains of infections as well as putting individual sequences in context. So far, phylogenetic analysis methods have recently found a broader application in this regard. Here we demonstrate that Principal Component Analy...
Open Access DOI:10.23937/2469-5793/1510126
Teenage Girl with Migraine Whose Symptoms Resolve with a Therapeutic Neck Exercise Program: A Case Report
Nasha Holt, MD and Codie Kurka, MS
Article Type: Case Report | First Published: August 03, 2020
A literature review reveals that neck pain is more commonly associated with migraine than is nausea, that reduced neck muscle function and reduced cervical range of motion is present in migraineurs that is not documented in those without migraine, and that there is pharmacological overlap in the treatment response of migraine and neck pain associated with migraine. We report the case of a teenage girl with right-sided migraines without aura whose symptoms resolve over a 3-month period in respons...
Open Access DOI:10.23937/2378-2951/1410195
Extensive Coronary Thrombus in Patients Presenting with STEMI and COVID-19 Infection
Angela Li, MD, Calvin Ngai, MD, Loukas Boutis, MD and Bani M Azari, MD, PhD
Article Type: Case Series | First Published: August 13, 2020
The pathophysiology of ST-elevation myocardial infarction (STEMI) is not well understood in Coronavirus disease 2019 (COVID-19). We present similar angiographic findings in two COVID-19 patients with STEMI. Despite percutaneous coronary intervention (PCI), distal coronary flow was not restored. The pro-thrombotic and inflammatory effects of COVID-19 may lead to myocardial infarction. The COVID-19 pandemic has caused a significant strain on global healthcare systems. STEMI management during this ...