Open Access DOI:10.23937/2474-3682/1510159
A Neglected Case of Popliteal Pterygium Syndrome Presenting in Adulthood
Shilpi Karmakar, M.Ch and Brijesh Mishra, M.Ch
Article Type: Image Article | First Published: October 26, 2020
Popliteal Pterygium Syndrome (PPS) is autosomal dominant syndrome with incomplete penetrance and variable expressivity. We report a case of 18-year-old female, who had repair of cleft of lip and palate in childhood, and now presented with paramedian bilateral lower lip pits. Examination revealed her to be a case of sporadic PPS. A comprehensive plan of management was formed, but the patient was lost to follow-up. We report the case for the purpose of educating the clinicians of this rare syndrom...
Open Access DOI:10.23937/2377-9004/1410180
Meconium Peritonitis: In Utero Diagnosis of a Rare Clinical Entity and Postnatal Outcome
Sarita Agrawal, MD, FICOG, FIAMS, FCGP, Arpana Verma, MS, Sarita Rajbhar, MS, Pushpawati Thakur, MD, Loukya Kodumuri, MBBS and Swati Kumari, MS, FNB
Article Type: Case Report | First Published: October 23, 2020
Meconium peritonitis (MP) is a rare cause of non-immune hydrops with reported incidence of 1:35,000 live births. MP is defined as an aseptic localized or generalized peritonitis caused due intrauterine bowel perforation and extravasation of the meconium. Few causes which might result in perforation include Ileal atresia, intussusception, Hirschsprung’s disease, cystic fibrosis, volvulus, colonic atresia, Meckel diverticulitis and vascular insufficiency. Successful outcome with conservative man...
Open Access DOI:10.23937/2572-4061.1510035
A Comprehensive Assessment of Hepatotoxicity Induced by Engineered Nanoparticles- A Review
S V S Rana
Article Type: Review Article | First Published: October 17, 2020
Liver is the major detoxifying centre of the body. It removes xenobiotics and their metabolites through metabolism or biliary excretion. Hepatocytes constitute 80% of total liver mass and play a major role in storage, synthesis, metabolism and redistribution of essential molecules. Liver has been known to accumulate > 90% of nanomatrerials translocated from other organs. Bioconcentration of nanoparticles may lead to impairment of structure and function of hepatic cells. Therefore, it is critical...
Open Access DOI:10.23937/2469-5858/1510100
Elder Abuse: Characterization of a Population Hospitalized in CHUC
Antony Soares Dionísio, João Filipe Gomes and Manuel Teixeira Marques Veríssimo
Article Type: Original Research | First Published: October 22, 2020
The main purpose of this study is to assess the prevalence of elder abuse in Portugal, more specifically in a central hospital in Coimbra and its impact on victims’ health. The analysis of the results concludes that 36% of the participants report experiencing at least one indicator of abuse. There is a relation between the number of abuse indicators and the female gender, low educational level, depressive symptoms, increased functional dependence and health status. Mistreatment in the elderly ...
Open Access DOI:10.23937/2469-5793/1510129
Factors Affecting Initiation of Breast Feeding: A Cross Section Study
Mayasah A. Sadiq and Alaa A. Salih
Article Type: Research Article | First Published: October 19, 2020
Breastfeeding is the ideal and most natural way of nurturing infants. Mother’s milk is the most complete food in the first months of life. According to the American Association of Pediatrics (AAP) guidelines, mother's milk must be started immediately after delivery and it must be considered as the only food of baby in the first six months of life and then it should be preserved one year as one of the main components in the diet of a child. A cross-sectional study conducted from February to May...
Open Access DOI:10.23937/2572-4045.1510056
Therapeutic Plasma Exchange in Small-Bowel Transplant Recipients
Aleh Bobr, MD, Whitney L Reid, DO, Sara M Shunkwiler, MD, Jesse L Cox, MD, PhD and Scott A Koepsell, MD, PhD
Article Type: Original Article | First Published: October 26, 2020
Therapeutic plasma exchange (TPE) is an important adjunct therapy to reduce levels of donor-specific antibodies (DSAs) associated with antibody mediated rejection (AMR) in solid organ transplant recipients, especially kidney recipients. The purpose of this study was to examine the effect of TPE on DSAs and clinical/pathologic evidence of rejection in small bowel transplant recipients. ...
Open Access DOI:10.23937/2572-4045.1510055
The Impact of Different Induction Immunosuppressive Therapy on Long Term Kidney Transplant Function When Measured by Iothalamate Clearance
Tambi Jarmi, MD, Samir Khouzam, MD, Nitika Shekhar, Launia White, BS, David O Hodge, Martin L Mai, MD and Hani M Wadei, MD
Article Type: Original Article | First Published: October 17, 2020
Improvement in short term outcomes after kidney transplant has been achieved by using different induction and maintenance therapeutic approaches. Long term outcomes have not matched the expectations of the transplant stakeholders. Our study aimed to address the early impact of induction agents on long term outcome of kidney transplant when measured by Iothalamate clearance. All adult kidney transplant recipients between January of 2012 and December of 2016 were reviewed. 649 patients were divide...
Open Access DOI:10.23937/2643-461X/1710037
Detecting Mycobacterium ulcerans in Clinical Specimens from Ghana: Comparative Evaluation of BU-LAMP and IS2404 PCR
Enoch Aninagyei, Rufai Tanko, Comfort Dede Tetteh, Kofi Adjei Ntiri, Mathias Dongyele, Alex Boye and Desmond Omane Acheampong
Article Type: Research Article | First Published: October 19, 2020
Conventional and nested polymerase chain reaction (PCR), and loop-mediated isothermal amplification (LAMP) have been used to identify Mycobacterium ulcerans in separate studies and different specimens. However, the sensitivities of these three techniques have not been compared in a single study. Samples were collected from patients suspected of Buruli ulcer disease (BUD) in Southern Ghana. Ulcerative and non-ulcerative forms of the disease were swabbed and aspirated respectively. Insertion seque...
Open Access DOI:10.23937/2469-5769/1510070
Our Experience Treatment Inhalation Injury in Children in Uzbekistan
Babur M Shakirov, PhD and Noila Ashurova, MD
Article Type: Research Article | First Published: October 23, 2020
Thermal inhalation injury is one of the factors aggravating the course of burn disease and resulting in patient’s death. According to literary data, damage to respiratory tract occurs approximately in 30% of cases with severe burn injury. Thermal inhalation injury severity can be determined not so much by airway burns but by toxic inhalation damage to the lungs and whole body with high toxic gaseous and vaporized chemical components of smoke. During a 3 year period 28 children with deep burns ...