Open Access DOI:10.23937/2378-3672/1410062
Immuno-Therapy in Lung Cancer - How Does Immuno-therapy for Lung Cancer Change Patients' Vision?
Tshetiz Dahal, MBBS
Article Type: Research Article | First Published: March 23, 2022
Survival rates of metastatic lung cancer including non-small cell lung cancer (NSCLC) and poor lung cell cancer (SCLC) are poor with a survival rate of less than 5%. The use of cell-oriented therapies has improved the overall survival of the median (OS) in a limited group of NSCLC patients whose tumors undergo certain genetic mutations. However in a large group of NSCLC and SCLC cell mutations are not available to lead to targeted targeted treatment. Recent positive results from new medical rese...
Open Access DOI:10.23937/2643-3885/1710065
Expedited Diagnosis and Surgical Repair of Isolated Acute Anterior Tibial Tendon Rupture: A Case Report
Shilpa Sharma DPM, Josh B Moosikasuwan MD and Jalukumar Patel, DPM, FACFAS
Article Type: Case Report | First Published: March 25, 2022
Isolated acute anterior tibial (AT) tendon rupture is rare and can be missed, resulting in significant functional deformity of the affected limb. Early surgical treatment can improve functional patient outcomes, familiarity with patient presentation, including a history of ankle pain and swelling after hyper-plantar flexion and signs of a palpable dell and weak dorsiflexory strength at the ankle, and prompt confirmation with MRI are crucial. Here we report a patient who had an isolated acute AT ...
Open Access DOI:10.23937/2474-3674/1510143
Comparison of High-Dose, Short-Term Steroid and Low-Dose Long Term Steroid Use in ARDS Caused by COVID-19
Suna KOC, MD and Ilke KUPELI, MD
Article Type: Original Article | First Published: March 19, 2022
We aimed to compare the 15-day continuous hemodynamic, laboratory and clinical course of patients with ARDS due to COVID-19 who received short-term highdose and long-term low-dose systemic methylprednisolone. Two hundred and two patients were recorded to be diagnosed with ARDS due to COVID 19 in the intensive care unit between June 1, 2020 and February 1, 2021. Patients were received systemic methylprednisolone for the short or long term and high or low doses were applied. Age, gender, APACHE II...
Open Access DOI:10.23937/2474-3674/1510142
Chest X-Ray Findings in Asthma Exacerbation and the Association with Acute Asthma Management among Children
Gul Sher, Fernanda E Kupferman and Mohamed Gaffoor
Article Type: Original Article | First Published: March 19, 2022
The National Heart and Lung Institute’s guidelines advise against routine use of chest X-ray (CXR) for acute asthma exacerbation. Despite this recommendation, unnecessary CXR are still being performed. The objective of this study is to assess the association between abnormal CXR findings and the severity of asthma exacerbation and its impact on acute asthma management. A retrospective chart review was performed of all pediatric patients 2-17 years of age who presented to the emergency departme...
Open Access DOI:10.23937/2469-5696/1410074
Melphalan and Cytarabine as a Salvage Therapy in Children with Relapsed or Refractory Acute Leukemia
Malaval Carmen Isolde, MD, Queudeville Manon, MD, Döring Michaela, MD, Hartmann Ulrike, Dr. Pharm, Lang Peter, MD, Handgretinger Rupert, MD and Ebinger Martin, MD
Article Type: Research Article | First Published: March 16, 2022
In refractory or relapsed acute leukemia the achievement of a complete remission by a salvage therapy and the performance of allogeneic hematopoietic stem cell transplantation (HSCT) is in most cases the only treatment by which long term disease-free survival can be accomplished. With current salvage regimens a 5 year overall survival rate of 29% is obtained in children with relapsed acute myeloid leukemia (AML) and a 10 year overall survival rate of 36% in children with relapsed acute lymphobla...
Open Access DOI:10.23937/2469-5742/1510080
Risk Factors for Vaginal Exposure in Women Requiring Mesh Sling Removal
Jacqueline A Chavez, Carlos Finsterbusch, MD, Dayron Rodriguez, MD, Himanshu Aggarwal, MD, Alana L Christie, MS and Philippe E Zimmern, MD, FACS, FPMRS
Article Type: Original Article | First Published: March 25, 2022
To evaluate risk factors for vaginal mesh exposure (VME) after mid-urethral sling (MUS) placement for urinary incontinence. This is a case-controlled retrospective study at a tertiary care center. An institutional review boardapproved database of women who underwent MUS suburethral excision procedure was reviewed. Demographic data, presenting symptoms, MUS placement technique, and location/size of exposure (none, < 1 cm, or > 1 cm) were collected for those who underwent MUS removal for symptomat...
Open Access DOI:10.23937/2643-4512/1710074
Effects of Workplace Configurations on Frontline Physiotherapists in Public and Private Hospitals in Brazil during the Covid-19 Pandemic
Rodrigo Gonçalves dos Santos, Arlindo Souza Amaral Neto, Mônica Ferreira da Silva, Paulo Victor Rodrigues de Carvalho and Alessandro Jatobá
Article Type: Original Article | First Published: March 18, 2022
The work of physiotherapists in handling Covid-19 patients depends on the severity of the patient condition. These workers rely on adequate workplaces, especially Intensive Care Units (ICU), where critical patients are handled. Private and public hospitals in Brazil dealt differently with the demands imposed by the Covid-19, and consequently, workers in public and private hospitals had to rely on distinct working conditions. Thus, this article aims to identify the possible risks, and the effects...
Open Access DOI:10.23937/2469-5823/1510171
COVID-19 Vaccines: Pharmacy Student Virtual Education Outreach Increases Knowledge and Vaccine Willingness among a College Campus Community
Lacy La Fever, Joe Norton, Savannah Poole, Kendra Rice, Alexis Underwood and Amie J Dirks-Naylor
Article Type: Original Article | First Published: March 25, 2022
Vaccines have now been developed, however, a significant portion of the population are reluctant to become vaccinated. Research shows that education can increase trust in vaccines and increase vaccination rates. Thus, the objective of the study was to determine the impact of a virtual pharmacy student-led educational session on COVID-19 vaccine knowledge and vaccine acceptance among a college campus community. A synchronous Zoom education session provided information about COVID-19 and available...
Open Access DOI:10.23937/2474-3631/1510035
Association of Substance and Psychiatric Disorders with Health Care Utilization and Cost
David Cawthorpe, BSc, MSc, PhD
Article Type: Original Research | First Published: March 20, 2022
Few studies have directly examined the health care costs of those who suffer from mental disorder problems. The quality of administrative data has improved to the point where such study is currently possible. We report prevalence and cost results for 16 years of physician billing data comparing the health costs of groups with and without substance and/or other psychiatric disorders. A 16-year dataset containing 95846511 physician-assigned International Classification of Disease (ICD) diagnoses a...
Open Access DOI:10.23937/2378-3656/1410386
The Role of Dermatoscopy to Differentiate Vestibular Papillae from Condyloma Acuminate in a Pregnant Woman
Fatima Zahra Agharbi and A. Kelati and S. Chiheb
Article Type: Case Report | First Published: March 14, 2022
The vestibular papillae (VP) represent an anatomical variant of the normal genital epithelium and are probably the female equivalent of pearly penile papules. It is thought that they are present in 1% of women, and this low percentage may be due to their lack of knowledge by practitioners since their diagnosis are often wrongly spotted as condyloma acuminates warts and this can lead to aggressive investigations, therapy, and anxiety in patients hence the role of dermoscopy. Here, we present a ca...