International Journal of

Stem Cell Research & TherapyISSN: 2469-570X

Early Online

 Open Access DOI:10.23937/2469-570X/1410061

Human Umbilical Cord Stem Cells in Chitosan Attenuate Myocardial Injury in Rat Cardiac Infarction

Robert J Henning MD, Abraham Khan MD and Xiao Wang MD

Article Type: Original Article | First Published: June 24, 2019

Myocardial infarction (MI) is the leading cause of cardiovascular deaths and disability in the industrialized world. Although stem cells have been injected into hearts to limit MI damage, < 4% of stem cells remain in the heart for > 1 hour due to myocardial contractility which causes the rapid egress of the stem cells through the cardiac veins and lymphatics. We hypothesized that stem cells in chitosan gels would remain longer in the heart and therefore be more beneficial in MI repair....

 Open Access DOI:10.23937/2469-570X/1410060

Testicular Expression of SCP-3, Gfra, and Sca-1 in Induced Azoospermatic Male Mice Treated with Honey, Bovine Colostrum and Umbilical Cord Blood Derived Mesenchymal Stem Cells

Somia Hassan, Faten Zahran and Shimaa Watad

Article Type: Original Article | First Published: February 16, 2019

Infertility affects 15% of couples worldwide. It is estimated that roughly half of the infertility cases are due to male factors. Male infertility could be caused by various reasons including failure in spermatogenesis, defects in sperm transportation or accessory gland function, genetic or environmental factors, and sexual disorders. Among these causes, spermatogenic defect is the primary one in male infertility. Spermatogenesis is a sophisticated multistep process involving three major phases:...

 Open Access DOI:10.23937/2469-570X/1410059

Potential of Polycaprolactone Nanofiber Scaffold for Ex Vivo Expansion of Cord Blood-Derived CD34+ Hematopoietic Stem Cells

Seyed Hadi Mousavi, Saeid Abroun, Masoud Soleimani and Seyed Javad Mowla

Article Type: Research Article | First Published: February 07, 2019

An efficient and practical ex vivo expansion of cord blood hematopoietic stem cells as an alternative source of HSC transplantation is crucial in understanding the potential of HSC transplantation in treating or supportive therapy in a variety of hematologic and non-hematologic disorders. The aim of this study was an ex vivo expansion of cord blood hematopoietic stem cells in a novel three-dimensional polycaprolactone nanofiber scaffold coated with collagen....

Volume 6
Issue 1