Coronary Artery Involvement Following Kawasaki Disease: A Case Report of a 5 Month Old African Infant
Tumwebaze Hilda, Ndagiire Emma, Namuyonga Judith, Twalib Aliku, Lwabi Peter and Lubega Sulaiman
Article Type: Case Report | First Published: November 07, 2019
Kawasaki disease (KD) is an acute systemic vasculitis which progresses to cause coronary artery abnormalities as a complication. Echocardiographic and cardiac angiographic data indicate that 20-40% of untreated KD patients develop coronary artery abnormalities. However, majority of the lesions regress over time. Timely treatment with high dose intravenous immunoglobulins (IVIG) and high dose of aspirin has been found reduce the incidence of developing coronary artery aneurysms to 2%-3%. Data on ...
Relationship Between Mean Platelet Volume-to-Platelet Count Ratio and the Presence and Severity of Coronary Artery Ectasia
Ramazan Asoglu and Emin Asoglu
Article Type: Research Article | First Published: September 28, 2019
Atherosclerosis plays an essential role in the etiopathogenesis of coronary artery ectasia (CAE). The mean platelet volume/platelet count (MPV/PLT) ratio is a new biomarker, and increased MPV/PLT ratio was a predictor of cardiovascular mortality in patients with the acute coronary syndrome. We aimed to assess the association between the CAE and MPV/PLT ratio. The present study included 50 patients with CAE and 45 healthy subjects prospectively. The CAE was defined as dilation of the coronary art...
Clinical Significance and Applications of D-Ribose in Cardiovascular Disease
Melike Bayram, David Perkowski, JA St Cyr and William T Abraham
Article Type: Review Article | First Published: December 15, 2018
Cardiovascular disease is the leading cause of deaths worldwide. Myocardial ischemia, a common etiological factor in cardiovascular disease, lowers cellular high-energy phosphate levels, i.e. adenosine triphosphate (ATP), with an accompanying impairment in myocardial function. Furthermore, scientists have argued for the importance of ATP levels in supporting both systolic and diastolic function in heart failure. The magnitude of ischemic heart disease and congestive heart failure is generally we...
Sex-Related Risk of Myocardial Infarction: Insights from Path Analysis
Mohammad Reza Dayer, Vahideh-Sadat Nazemi, Mohammad Saaid Dayer and Sayed Mohammad Reza Alavi
Article Type: Research Article | First Published: November 19, 2018
Cardiovascular disease and myocardial infarction comprise the leading causes of more than half of the total death often among elderly people. Psychological stresses, imbalanced diet, sedentary lifestyle, obesity, tobacco, alcohol, and metabolic diseases such as hypothyroidism and diabetes mellitus are the main risk factors for the disease. In order to better understand the underlying risk factor for the disease we performed complete analyses of biochemical factors in sera of obese, non-diabetic ...
Takotsubo Cardiomyopathy Pathophysiology May Also Affect the Gut
Article Type: Case Report | First Published: November 19, 2018
In this report, we describe a patient who presented with transient acute abdomen before the onset of an acute myocardial ischemic event. Chest pain, dyspnea, and hypotension requiring vasopressors developed 2 days after the patient presented with paralytic ileus. Transient left-bundle-branch block and mildly elevated troponin and brain-natriuretic peptide levels occurred. Echocardiography and left ventricular angiography revealed extensive periapical akinesia and a left ventricular ejection frac...