Zaichick V, Zaichick S (2018) Br, Fe, Rb, Sr, and Zn Levels in the Prostatic Secretion of Patients with Chronic Prostatitis. Int Arch Urol Complic 4:046.


© 2018 Zaichick V, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

RESEARCH ARTICLE | OPEN ACCESS DOI: 10.23937/2469-5742/1510046

Br, Fe, Rb, Sr, and Zn Levels in the Prostatic Secretion of Patients with Chronic Prostatitis

Vladimir Zaichick1* and Sofia Zaichick1,2

1Radionuclide Diagnostics Department, Medical Radiological Research Centre, Russia

2Department of Medicine, University of Illinois College of Medicine, USA



Chronic prostatitis (CP) is an internationally important health problem of the man, particularly in developed countries. The aim of this exploratory study was to evaluate whether significant changes in the levels of Zn and some other trace elements of prostatic fluid exist in the inflamed prostate.


Prostatic fluid levels of Br, Fe, Rb, Sr, and Zn were prospectively evaluated in 33 patients with CP and 42 healthy male inhabitants. Measurements were performed using 109Cd radionuclide-induced energy dispersive X-ray fluorescent microanalysis. Prostatic fluid samples were divided into two portions. One was used for cytological and bacteriological investigations while the other was intended for trace element analysis.


Mean values ± standard error of means (M ± SΕΜ) for concentration (mg/L) of trace element in the expressed prostatic fluid (EPF) of normal prostate were: Br 2.86 ± 0.59, Fe 8.30 ± 1.42, Rb 1.16 ± 0.10, Sr 1.27 ± 0.17, and Zn 598 ± 34. It was observed that in the EPF of inflamed prostate content of Rb significantly increased whereas content of Zn decreased in a comparison with those in the EPF of normal prostate.


There are significant changes in trace element contents and their relationships in the fluid of CP prostate. The alterations in levels of Zn and Rb in the EPF of inflamed prostate might demonstrate an involvement of these trace elements in etiology and pathogenesis of CP. It was supposed that the changes of Zn and Rb levels in the EPF samples can be used as CP markers.