Retinoids and its derivatives are known to regulate tumor progression. Our previous study in Colorectal Cancer (CRC) has shown that the expression of LRAT, a gene converts excess retinol into retinyl ester to balance retinoids homeostasis, may be regulated by its promoter methylation status to modulate the retinoids synthesis....

All consecutive patients who underwent endoscopy in the years 2006-2015 in whom FGP's were seen were included. An extensive search was done in order to assess use of PPI's. As a control group all consecutive patients in 2012, in whom no macroscopic abnormalities were seen, were used....

The use of botanicals is increasingly throughout the world. They are ingredients of different types of products, such as herbal medicinal products, Plant Food Supplements (PFS), and functional foods. They are commonly taken to promote health and treat or prevent diseases, even if, in most of cases, there is no clear evidence of their clinical efficacy....