Journal of

Clinical Gastroenterology and TreatmentISSN: 2469-584X


 Open Access DOI:10.23937/2469-584X/1510049

LRAT Promoter Hypermethylation as a Prognostic Marker for Colorectal Cancer Impairs Retinol Metabolism

Vania DePaoli, Francis Barany and Yu-Wei Cheng

Article Type: Short Communication | First Published: September 30, 2017

Retinoids and its derivatives are known to regulate tumor progression. Our previous study in Colorectal Cancer (CRC) has shown that the expression of LRAT, a gene converts excess retinol into retinyl ester to balance retinoids homeostasis, may be regulated by its promoter methylation status to modulate the retinoids synthesis....

 Open Access DOI:10.23937/2469-584X/1510048

Presence of Fundic Gland Polyps in Patients Undergoing Upper Gastrointestinal Endoscopy: Incidence and the Relation with the Use of Proton Pump Inhibitors

RJLF Loffeld

Article Type: Research Article | First Published: September 30, 2017

All consecutive patients who underwent endoscopy in the years 2006-2015 in whom FGP's were seen were included. An extensive search was done in order to assess use of PPI's. As a control group all consecutive patients in 2012, in whom no macroscopic abnormalities were seen, were used....

 Open Access DOI:10.23937/2469-584X/1510047

A Case of Serial Liver Injury Induced by Plant Food Supplements in a Young Healthy Man

Gianluca Cappelleri, Enrico Sangiovanni and Mario Dell'Agli

Article Type: Case Study | First Published: July 08, 2017

The use of botanicals is increasingly throughout the world. They are ingredients of different types of products, such as herbal medicinal products, Plant Food Supplements (PFS), and functional foods. They are commonly taken to promote health and treat or prevent diseases, even if, in most of cases, there is no clear evidence of their clinical efficacy....

Volume 3
Issue 3