Open Access DOI:10.23937/2643-4539/1710025

Medium-Term Effect of Pedunculopontine Nucleus Neurotoxic Lesion on Motor Function and Gene Expression of Protein Related to Dopaminergic Homeostasis in Rat

Lisette Blanco-Lezcano, María Elena González-Fraguela, Guadalupe Zaldívar-Lelo de Larrea, Rosa Martha Pérez-Serrano, María Daniela Frade-Pérez, Teresa Serrano-Sánchez and Liliana Francis Turner

Article Type: Original Article | First Published: 2023/04/14

The hypothesis that early degeneration of the pedunculopontine nucleus (PPN) may be related to nigral degeneration has opened new avenues of basic research for this disease. It is not known how the motor function and nigrostriatal gene expression of TH, VMAT2 and DAT behave in an intermediate term (30 days) following the pontine lesion....

 Open Access DOI:10.23937/2378-2951/1410275

Non-Uremic Calciphylaxis in Patient of Non Recovered Postpartum Cardiomyopathy with Apla Syndrome

Aman Makhija, Jignesh Vanani, Arun Mohanty, Manchanda SG, Shashi Dhawan, Shilpa Garg, Manish Malik and Mantri RR

Article Type: Case Report | First Published: 2023/04/30

Calciphylaxis is rare, life-threatening calcific uremic arteriolopathy in patients with end stage renal disease. Rarely, it can occur in patients with normal renal function known as non-uremic calciphylaxis. Very scant literature and few case reports are available about non-uremic calciphylaxis. We present a case of 51-year-old female with reduced LV ejection fraction as sequelae of peripartum cardiomyopathy on long term warfarin who presented with calciphylaxis lesions with normal renal functio...

 Open Access DOI:10.23937/2377-4630/1410157

Cardiac Anesthesia Management of an Acquired Methemoglobinemia Patient

E Kesimci, E Bihorac and A Sezgin

Article Type: Mini Review | First Published: 2023/04/27

Acquired methemoglobinemia occurs most commonly from the ingestion of medications or toxins that oxidize the ferrous iron of hemoglobin. Anesthetizing patients with methemoglobinemia is a highly specialized task. Nevertheless, cardiac anesthesia for these patients requires high attention on maintenance of precise O2 delivery to tissues. We herein, describe an uneventful course of an acquired methemoglobinemia patient having on pump mitral valve replacement and two coronary vessel bypass grafting...

 Open Access DOI:10.23937/2469-5823/1510184

Milk Moon and the Building of Bonds to be Born and to Live: A Necessary Reflection in the 21st Century

Semírames Cartonilho de Souza Ramos, Ana Lúcia Basílio Carneiro, Amanda Karolynne Gomes Chacon, Cíntia Bezerra Almeida Costa, Orácio Carvalho Ribeiro Jr and Roziane Marinho Ribeiro

Article Type: Original Research Article | First Published: 2023/04/17

The Milk Moon is a process of mothering, a humanised way of gestating, giving birth and physically and emotionally developing the mother-baby binomial and building identities, and can become an extremely rich period, of experiences, experiencing new realities and bonding between mother, baby and family. And in this process, the formation of the support network in the organisation of the Milk Moon in any context becomes a protective factor for the health of the mother-baby binomial....

 Open Access DOI:10.23937/2572-3243.1510121

Non-Invasive Biomechanical Intervention Leads to Low Rates of Total Knee Replacement and Reduced Utilization of Healthcare Resources among Older Adults with Chronic Knee Pain: A 5-Year Follow-Up Study

Shirley Shema-Shiratzky, Amit Mor and Avi Elbaz

Article Type: Original Article | First Published: April 30, 2023

This was a retrospective study among older adults with chronic knee pain, primarily due to OA, who received the biomechanical intervention between 2014 and 2017. An independent survey institute contacted patients between August and September 2022 to confirm their surgical status and utilization of other healthcare services, covering at least five years of follow-up....

 Open Access DOI:10.23937/2572-3243.1510120

An Intervention Program Based on Motor Coordination Principles Improves Knee Alignment in Pre-Professional Ballet Dancers

Monica de Oliveira Melo, Kaanda Nabilla Souza Gontijo, Claudia Tarrago Candotti, Gabriela Cristina dos Santos, Stephanie dos Santos Cardoso, Bruna Soares, Isis Juliene Rodrigues Leite Navarro and Jefferson Fagundes Loss

Article Type: Clinical Trial | First Published: April 30, 2023

The practice of classical ballet requires constant, prolonged physical training periods, and the repetition of aesthetic movements that exceed anatomical limits. Joint misalignment during sustained posture or movement execution is one of the principal risk factors for injury in the dance world....

 Open Access DOI:10.23937/2377-9004/1410240

A Case Report of Repeat Methotrexate Failure in Ectopic Pregnancy during In Vitro Fertilization

Carmine Guynn, PA-S and Kevin Alten, MD

Article Type: Case Report | First Published: April 14, 2023

Patients who undergo assisted reproductive technology, specifically in vitro fertilization (IVF), are at an increased risk of developing ectopic pregnancy. 90% are successfully treated with either single dose or multi-dose methotrexate intervention....

 Open Access DOI:10.23937/2377-9004/1410239

Cesarean Delivery in Extracorporeal Membrane Oxygenation Dependent COVID-19 Parturients: A Case Report

Sannoor S Syed, MD, Abigail O Souryal, MD, Emily H Adhikari, MD, Kelechi B Anyaehie, MD, Joo H Shin, MD, Miakka N Jalloh, MD, Matthew J Leveno, MD, Pamela E Fox, MD and Olutoyosi T Ogunkua, MD

Article Type: Case Report | First Published: April 13, 2023

This case report describes two cases of unvaccinated pregnant patients with COVID-19 who progressed to ARDS requiring Venovenous (VV)-ECMO and successfully underwent cesarean delivery. The patients provided Health Insurance Portability and Accountability Act authorization and consent to publish these reports. This article conforms to case report (CARE) guidelines....

 Open Access DOI:10.23937/2377-9004/1410238

Pregnancy Complicated by Non-Compaction Cardiomyopathy in the Mother and Fetus: A Case Report of Both Maternal Management and Prenatal Diagnosis

Eileen O'Connor, DO, Leah Saylor, DO, Suzanne O'Nan, MD and William Schnettler, MD

Article Type: Case Report | First Published: April 13, 2023

Left ventricular noncompaction cardiomyopathy (LVNC) is a rare form of familial cardiomyopathy attributed to failure of ventricular compaction during embryogenesis. Scant data exists regarding the management approach to pregnant patients with this condition. Additionally, few cases are reported in which both the mother and fetus are simultaneously affected by this condition during the antepartum period. ...

 Open Access DOI:10.23937/2643-4474/1710134

Combined Biopsy and Endoscopic Third Ventriculostomy in Third Ventricular Glioblastoma

Jeyhun Farzullayev, Mazin Omer, Daniel Pielenz, Michael Brodhun, Julian Rathert, Steffen K Rosahl and Ruediger Gerlach

Article Type: Case Report | First Published: March 31, 2023

Glioblastoma is the most common intrinsic brain tumor. Albeit often located adjacent to the ventricular system, intraventricular glioblastomas are rare. We present a case of a third ventricular glioblastoma and discuss effective diagnostic and therapeutic options....