Open Access DOI:10.23937/2377-9004/1410032
Blasts on Blood Film after Treatment of Ovarian Cancer
Heong V, Duong B and Wong S
Article Type: Case Report | Publication Updated: April 13, 2015
A 40 year old female with a history of hypertension, depression and menorrhagia was admitted with a one week history of flu like symptoms, lethargy and neutropenia. Two years prior to admission, she was diagnosed with FIGO Stage IIC clear cell epithelial ovarian cancer and underwent a total abdominal hysterectomy and bilateral salphingo-oophorectomy (optimal debulking)....
Open Access DOI:10.23937/2378-2951/1410026
Association between Syncope and Myocardial Bridge
Lins TCB, Valente LM, Oliveira KTMN and Brandao SCS
Article Type: Case Report | Publication Updated: April 10, 2015
Myocardial bridge is a cause of sudden death in athletes, but syncope is somewhat related to this disease symptom. This paper reports a case of a young athlete, swimming practitioner with syncopal episodes related to physical exertion....
Open Access DOI:10.23937/2469-570X/1410007
Enhancement of Human Adipose-Derived Stem Cell Expansion and Stability for Clinical use
Swenn Maxence Krähenbuhl, Anthony Grognuz, Murielle Michetti, Wassim Raffoul and Lee Ann Applegate
Article Type: Research Article | Publication Updated: April 06, 2015
Co-culture techniques associating both dermal firoblasts and epidermal keratinocytes have shown to have better clinical outcome than keratinocyte culture alone for the treatment of severe burns. Since fat grafting has been shown to improve scar remodelling, new techniques such as cell-therapy-assisted surgical reconstruction with isolated and expanded autologous adipose-derived stem cells (ASCs) would be of benefit to increase graft acceptation....
Open Access DOI:10.23937/2469-5769/1510003
Short Lingual Frenulum and Obstructive Sleep Apnea in Children
Yu-Shu Huang, Stacey Quo, J Andrew Berkowski and Christian Guilleminault
Article Type: Research Article | Publication Updated: April 08, 2015
A retrospective study of prepubertal children referred for suspicion of obstructive sleep apnea, found 27 subjects with non-syndromic short lingual frenulum. The children had findings associated with enlarged adenotonsils and/or orofacial growth changes....
Open Access DOI:10.23937/2378-3001/2/1/1027
Marburg's Variant of Multiple Sclerosis with Extensive Brain Lesions: An Autopsy Case Report
Ayumi Ludwig, Jaclyn Duvall, Jo Elle Peterson and Ryan Hakimi
Article Type: Case Report | Publication Updated: April 10, 2015
Marburg's variant of multiple sclerosis (MS) is a malignant and rapidly progressive form of MS that typically leads to deterioration or death within weeks to months. Here we present a case involving a 25-year-old woman who presented with fluctuating mild encephalopathy of one-week duration who progressed to coma and ultimately died on day seven after being admitted to our university based neurosciences intensive care unit (NSICU)....
Open Access DOI:10.23937/2378-3001/2/1/1026
Atypical Antipsychotic Drugs in Dual Diagnosis Patients: A Review
Marta Marin-Mayor, Jorge Lopez-Alvarez, Francisco Lopez-Munoz, Francisco AriasHorcajadas and Gabriel Rubio
Article Type: Review Article | Publication Updated: March 30, 2015
Dual Diagnosis (DD), defined as the co-occurrence of a Substance Use Disorder (SUD) and a Severe Mental Illness (SMI), is associated with several negative outcomes. Typical antipsychotics (TAP) are not of great value for patients with DD as they are associated with poorer responses and can worsen SUD. Atypical antipsychotics (AAP) offer several advantages compared to TAP....
Open Access DOI:10.23937/2469-5726/1510008
Osteoimmunological Aspects on Inflammation and Bone Metabolism
Uwe Lange, Gabriel Dischereit, Elena Neumann, Klaus Frommer, Ingo H. Tarner and Ulf Muller-Ladner Kerckhoff-Klinik
Article Type: Review Article | Publication Updated: April 09, 2015
Bone remodelling is characterized by a balance between bone resorption and bone formation. The osteoblasts are responsible for bone synthesis and the osteoclasts for bone resorption. A finely adjusted interaction between molecular mechanisms results, via cytokines, hormones and growth factors, in homeostasis of bone metabolism....
Open Access DOI:10.23937/2378-346X/1410021
A Test for Progressive Myopia and the Role of Latent Accommodation in its Development
Kodikullam V Avudainayagam, Chitralekha S Avudainayagam and Nicholas H Nguyen
Article Type: Research Article | Publication Updated: April 10, 2015
Purpose: To determine whether those myopes who respond like hyperopes when tested with a multivergence hologram are progressive myopes and to investigate the role of latent accommodation in the development of progressive myopia. Methods: Recently, we introduced a specially designed hologram to test the vision of spectacle corrected subjects. A subject viewing through this hologram would see the real and virtual images of different test letters at various distances....