Open Access DOI:10.23937/2469-570X/1410008

The Decision for Regenerative Endodontic Therapy

Anastasia Agrafioti, Maria Deimezi and Evangelos G. Kontakiotis

Article Type: Review Article | First Published: April 19, 2015

Regenerative endodontics is described as biologically based procedures designed to replace damaged structures, including dentin and root structures, as well as cells of the pulp-dentin complex, and is considered as an optimal approach for treating the immature permanent tooth with a necrotic pulp....

 Open Access DOI:10.23937/2378-3656/1410029

Ruptured Intracranial Teratoma: A Case Report and Literature Review

Luis R. Romero, Betty Y. Chen, Miguel A. Guzman, Yihua Zhou, Jin-Ping Lai and Fang Xiang Chen

Article Type: Case Report | First Published: May 20, 2015

Teratomas are germinal cell tumors originating from all three germ cell layers. When intracranial in location, they typically occur in the pineal or suprasellar regions. Ruptured intracranial teratomas are exceedingly rare. The authors report a case of a 34-year-old woman with a ruptured fourth ventricular mature teratoma that was treated with open surgery. The patient initially presented complaints of headache, nausea, and dizziness....

 Open Access DOI:10.23937/2378-3672/1410011

High Temperature Affects Cytokine Release by Human Peripheral Blood Mononuclear Cells

Hanna Bessler and Meir Djaldetti

Article Type: Research Article | First Published: May 23, 2015

Fever is one of the leading signs of the inflammatory process and it is one of the mechanisms that activate the immune system to defend the organism from various pathogens. For this goal, the peripheral blood mononuclear cells (PBMC) are among the first to be mobilized by triggering their capacity for phagocytosis and inflammatory cytokine production....

 Open Access DOI:10.23937/2378-3672/1410010

Fatal Good's Syndrome: Report of Two Cases

Musabak Ugur, Kartal Ozgur, Demirel Fevzi, Gulec Mustafa, Safali Mukerrem, Battal Bilal, Nevruz Oral, Baysan Abdullah, Yesillik Sait, Karaman Murat and Sener Osman

Article Type: Case Report | First Published: May 20, 2015

Good's syndrome (GS) that consists of hypogammaglobulinemia and thymoma is a rare adult-onset disease. Some paraneoplastic syndromes like pure red cell aplasia (PRCA) and myasthenia gravis (MG) may accompany to this immunodeficiency disease. We herein reported two fatal cases of GS....

 Open Access DOI:10.23937/2377-4630/2/3/1030

Perceptions and Attitudes of Anesthesiologists toward Pain Management: A Survey of Pain Categories

David D. Nguyen, Daneshvari Solanki, Christopher Babl, Nikolaus Gravenstein and Rene Przkora

Article Type: Commentary | First Published: May 30, 2015

Pain is a global epidemic and in America is considered the fifth vital sign. It causes significant suffering and disability, and pain contributes to massively increased healthcare costs. Effective pain management is an important outcome and quality measure....

 Open Access DOI:10.23937/2469-5718/1510007

Effectiveness of Bracing and Taping, and the Influence of Light Finger Touch, During Unexpected Ankle Inversion Perturbations

J. Daniel Freedman, Youngmin Jun, David A. Humphreys and James P Dickey

Article Type: Orginal Research | First Published: May 15, 2015

Ankles are the most frequent site of musculoskeletal injury and a major cause for lost time in sports. Taping and bracing are commonly used to support unstable ankle joints. The purpose of this project was to evaluate whether taping or bracing effectively reduce ankle motion, or alter the timing or amplitude of muscle activation, during unexpected perturbations. 14 male subjects stood on their right foot on an inversion motion platform and underwent a sudden inversion....

 Open Access DOI:10.23937/2378-346X/1410022

Intravitreal Anti-Vascular Endothelial Growth Factor Complications

Sergio Rojas J MD, Jorge A Sanchez R MD , Adriana Saucedo C MD, Benito Celis S MD, Carla R Perez M MD, Itzel Espinosa S MD, Araceli Rojas D MD, Angeles Hernandez V MD, Arthur Levine B MD, and J Abel Ramirez E MD

Article Type: Research Article | First Published: May 11, 2015

The use of antiangiogenic drugs (anti-VEGF) has been described in several retinal diseases, so their use has become a common practice in most eye centers around the world. Since its application involves an invasive procedure, several complications have been described associated with their use, including from subconjunctival hemorrhage to devastate endophthalmitis....

 Open Access DOI:10.23937/2469-5823/1510002

Educational Intervention to Improve Nursing Practice in the Critical Care Setting

Ann-Charlotte Falk

Article Type: Research Article | First Published: May 26, 2015

A variety of educational interventions may have an impact on patient assessment and patient outcome. Studies have reported an inconsistency in the use of Neurological assessments performed by nurses, such as the Glasgow Coma Scale (GCS) in the acute care setting. The aim of this study is to evaluate the impact of an educational intervention for nurses on the number of performed neurological assessments over time....

 Open Access DOI:10.23937/2469-5718/1510006

Influence of 120-Day Stimulated Microgravity with Countermeasures on Human Muscle Musculo-Tendinous Stiffness and Contractile Properties

Yuri A Koryak

Article Type: Research Article | First Published: May 15, 2015

It is well known that the unloading of the musculoskeletal system by actual or simulated microgravity causes numerous changes in the musculoskeletal system, such as muscular atrophy and decreased contraction strength, both after relatively short-term (10-17) and long-term (>5 weeks) periods of unloading. The deterioration of musculoskeletal function causes no direct health hazards and does not affect the capacity for work during short-term space missions....

 Open Access DOI:10.23937/2469-5696/1410013

Fetal and Neonatal Alloimmune Thrombocytopenia: Advances in Laboratory Diagnosis and Management

Hacene Brouk and Hanifa Ouelaa

Article Type: Review Article | First Published: April 30, 2015

Fetal and neonatal alloimmune thrombocytopenia (F/NAIT), caused by fetomaternal mismatch for human platelet (PLT) alloantigens (HPAs), is the commonest cause of severe thrombocytopenia in term neonates and is analogous to the fetal/neonatal anaemia caused by haemolytic disease of the newborn (HDN). The most feared complication of this syndrome is the occurrence of intracranial hemorrhage leading to death or neurological sequels....