Open Access DOI:10.23937/2469-5696/1410014
Pediatric B-cell Non-Hodgkin Lymphoma: 21-year Experience with FAB-LMB Protocols in a Single Institute in Greece
Apostolos Pourtsidis, Marina Servitzoglou, Margarita Baka, Despina Bouhoutsou, Maria Varvoutsi, Dimitrios Doganis, Katherine Strantzia-Michail and Helen Kosmidis
Article Type: Research Article | First Published: May 10, 2015
Aims and background: Our objective was to analyze the clinical and demographic characteristics of children with B-cell lymphoma treated in a single center over the last two decades. Methods: Data was collected by a retrospective review of the charts of all 76 patients treated to our unit, from 1990 to 2010, with FAB LMB 89, 96 protocols and 2003 modifications....
Open Access DOI:10.23937/2378-346X/1410023
Incidence of Ocular Hypertension Following Silicone Oil Use after Vitrectomy Surgery
Ashiyana Nariani, Nitasha Khanna, Arthi Chawla, Rominder Momi, Anna Gabrielian and Seenu M. Hariprasad
Article Type: Research Article | First Published: May 14, 2015
Background and objective: Silicone oil (SO) is important in vitreoretinal surgery. The incidence of glaucoma after silicone oil tamponade (SOT) was investigated. Study design/patients and methods: A retrospective chart review of patients with SOT at the University of Chicago from 2005 to 2008 was conducted to determine the incidence of Silicone Oil Induced Ocular Hypertension (SOIOH). IOP in the SOIOH and SOIOH free groups was compared with the paired t-test....
Open Access DOI:10.23937/2377-9004/1410041
Mayer-Rokitansky-Kuster-Hauser Syndrome - Case report
Rodrigo Dias Nunes and Djulie Anne de Lemos Zanatta
Article Type: Case Report | First Published: June 02, 2015
This is the report of a teenager student with primary amenorrhea with secondary sexual characteristics. The incidence of Mayer- Rokitansky-Kuster-Hauser syndrome was not clearly established, but studies indicate a variation of 1/4,000 and 1/5,000 live births of the female sex. The syndrome is characterized by aplasia of the Mullerian duct on a person who has karyotype 46, XX with female phenotype characteristic of primary amenorrhea in adolescence. Treatment is usually delayed until the patient ...
Open Access DOI:10.23937/2469-5726/1510014
Treatment of Refractory Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis with High Dose Anakinra
Kwong Jenitta M, Peng Tammy, Mohiuddin Adil, Chefiz Dalya, Craig Vicki, Weissmann David, Moorthy L Nandini, Weiss Pamela F, Cron Randy Q and Andujar Joanna
Article Type: Case Report | First Published: June 11, 2015
We report a case of MAS occurring during the initial presentation of sJIA treated with high dose anakinra. Excess interleukin-1 can lead to the clinical and laboratory findings of sJIA and MAS, and the up regulation of interleukin-6. Uncontrolled production and activation of macrophages and T lymphocytes lead to MAS manifestations, including prolonged high fever, pancytopenia, coagulopathy, lymphadenopathy, hepatic insufficiency, and neurologic dysfunction....
Open Access DOI:10.23937/2469-5726/1510013
Effect of Etanercept on Anti-Carbamylated Protein Antibodies in Patients with Rheumatoid Arthritis
Francesca Romana Spinelli, Arbi Pecani, Fulvia Ceccarelli, Cristiano Alessandri and Fabrizio Conti
Article Type: Research Article | First Published: May 23, 2015
Rheumatoid Arthritis (RA) is a systemic, chronic inflammatory disease characterized by inflammation of synovial joints and production of autoantibodies such as Rheumatoid Factor and antibodies directed against modified proteins - i.e. anti-citrullinated peptides antibody (ACPA). Carbamylation, as a post translational modification, has been recently associated to RA since anticarbamylated protein antibodies (anti-CarP) have been detected in the sera of RA patients. The effect of treatment on anti...
Open Access DOI:10.23937/2377-9004/1410040
Leiomyosarcoma of the Right Iliac Veins Presenting as a Pelvic Mass: A Case Report
E.Tripodi, V. Zanfagnin, C. Fava, P. Zola and A. Ferrero
Article Type: Case Report | First Published: May 30, 2015
Leiomyosarcoma of the iliac veins is a very uncommon tumour. Prognosis is usually poor and the best treatment is unknown. Case report: We report the case of a 74-year-old woman presenting a right leg oedema. Venous colour doppler was normal. Abdominal ultrasound and magnetic resonance scanning demonstrated a 70 mm mass in the right pelvis with a well-defined profile, which was not homogeneous after contrast enhancement....
Open Access DOI:10.23937/2377-9004/1410039
Long Term Triptorelin Therapy in a Large Endometriosis Nodule Arising in an Episiotomy Scar
Basma Darwish, Gregoire Leleup, Cecile Martin and Horace Roman
Article Type: Case Report | First Published: May 26, 2015
Endometriosis is the extra-uterine presence of endometrial glands and stroma, most often in the pelvis. It is very occasionally found in extra-abdominal sites. Perineal endometriosis is the presence of endometrial tissue in the perineal sites. Endometriosis of the perineum and vulva is extremely rare, with the most common site being episiotomy scars....
Open Access DOI:10.23937/2469-5807/1510004
Proficiency Assessment Mechanism for Line-Probe Assay Testing for Diagnosis of Multidrug-Resistant Tuberculosis in India
Raizada N, Sachdeva KS, Malhotra B, Thakur R, Kishore Reddy VC, Chauhan DS, Dave P, Mohammed F, Ram Das, Sharma P, Sharma SK, Wares F, Sahu S, O'Brien R, Mundade Y, Dewan PK and Paramasivan CN
Article Type: Research Article | First Published: June 08, 2015
GenoType MTBDRplus assay (LPA) has been endorsed by the World Health Organization for rapid screening of patients at risk of MDR-TB for an early diagnosis. A key constraint in the uptake of this technology in 2009 was the lack of LPA proficiency assessment system. To enable LPA scale-up, proficiency testing procedures were developed and implemented in India. Methods: After initial LPA training, each project site collected remnant sputum specimens from 50 smear-positive patients for anonymous LPA...
Open Access DOI:10.23937/2378-2951/1410035
Early Administration of Tirofibanin Mid- to High-risk Patients with Non-ST Elevation Acute Coronary Syndrome Referred for Elective Percutaneous Coronary Intervention (ETN-STEP): A Multi-center Randomized Controlled Clinical Trial in China
Jianping Li, Bo Zheng, Xingang Wang, Tieci Yi, Wei Dong, Zhan Gao, Shaoping Nie, Yawei Luo, Xiaobo Mao, Xi Su, Hui Chen, Ning Tan, Xufen Cao, Jun Zhang and Yong Huo
Article Type: Review Article | First Published: June 08, 2015
The objective of this randomized controlled clinical trial was to evaluate the efficacy and safety of upstream administration of Tirofiban in mid- to high-risk patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) undergoing early percutaneous coronary intervention (PCI)....
Open Access DOI:10.23937/2378-2951/1410034
An Update on Peripartum Cardiomyopathy in the 21st Century
Kavita Sharma and Stuart D Russell
Article Type: Review Article | First Published: June 02, 2015
Peripartum cardiomyopathy (PPCM) is a pregnancy-associated idiopathic cardiomyopathy secondary to marked left ventricular systolic dysfunction. The disease presents towards the end of pregnancy through the first 5 months post-delivery, with ethnic and geographic variation in incidence and outcomes. While it is relatively rare, PPCM is associated with significant morbidity and can be fatal....