Open Access DOI:10.23937/2469-5718/1510013
Physiologic Responses to Two Distinct Maximal Cardiorespiratory Exercise Protocols
Rebecca D Larson, Gregory S Cantrell, Carl J Ade, John W Farrell III, David J Lantis, Monica A Barton and Daniel J Larson
Article Type: Research Article | First Published: July 05, 2015
Purpose: The purpose of this study was to compare physiologic responses elicited by a ramp protocol to those elicited by a staged protocol. Methods: 57 subjects were recruited and consented to be tested on two separate occasions across one week using a magnetically braked cycle ergometer. Expired gases were collected using a calibrated metabolic cart....
Open Access DOI:10.23937/2469-5696/1410015
The Role of Positron Emission Tomography Imaging in the Risk-Adapted Treatment of Stage I-II Hodgkin's Lymphoma - A Retrospective Analysis
Tom Rider, John Jones, John Brewin, Gillian Horne, Jack Wills, Hannah Barton, Kevin Boyd, Timothy Corbett, Sabina Dizdarevic and Timothy Chevassut
Article Type: Research Article | First Published: July 09, 2015
Early stage Hodgkin's Lymphoma (HL) has excellent outcomes and recent research has focused on minimising treatment-related toxicities. However, the role of 18F-florodeoxyglucose positron emission tomography (FDG PET) imaging in this setting is not fully determined. We retrospectively calculated overall survival (OS) and relapse free survival (RFS) in stage I-II HL when radiotherapy was omitted if post-chemotherapy FDG PET imaging was negative....
Open Access DOI:10.23937/2469-5823/1510003
Asking about Postpartum Depressive Symptoms - An Easy Way to Identify Maternal Distress at 18 Months?
Lagerberg D and Magnusson M
Article Type: Research Article | First Published: July 02, 2015
Aim: To determine whether a simple question about maternal recall of postpartum depressive symptoms could aid in identifying maternal distress at 18 months postpartum. Results: With one exception (spouse relationship stress), low PD mothers reported the most favourable and high PD mothers the least favourable outcomes in terms of stress, perceived child difficulty and problems handling child mobility, with medium PD mothers in between. All these differences were significant. Effect sizes were sm...
Open Access DOI:10.23937/2572-3987.1510001
Amitriptyline Therapy in Chronic Pain
Min Su, Liang Liang and Shengyuan Yu
Article Type: Review Article | First Published: June 26, 2015
Rodent evidence has confirmed the analgesic effect of tricyclic antidepressants in the treatment of chronic pain, which amitriptyline is rigorously verified. The analgesic effect of amitriptyline, whose mechanisms are complex and unclear, is different from its antidepressant effect. This article reviewed the mechanisms behind amitriptyline's analgesic properties to further understanding of this drug. Additionally, this article reviewed the clinical evidence of the effectiveness of amitriptyline ...
Open Access DOI:10.23937/2572-4010.1510005
Expectations from Body Contouring Surgery and Body-image Satisfaction in Post-Bariatric Patients
Robert Wenger, Mihai A. Constantinescu, Hugo B. Kitzinger and Daniel M. Frey
Article Type: Research Article | First Published: July 04, 2015
Because of the important developments in bariatric surgery over the last decade there is a significant increase in patients with sequelae of post-bariatric massive weight loss, which include skin- and soft tissue redundancy. These body contour deformities can be improved using plastic- and reconstructive surgery techniques. It remains unclear what percentage of post bariatric patients will eventually undergo body contouring surgery and what their body image and expectations are. The current stud...
Open Access DOI:10.23937/2378-346X/1410027
Free Flaps Reconstruction after Orbital Exenteration: A Single Centre Case Series
Saul N Rajak, Edwin Figueira, Natasha A Forster, Timothy Greenwell, Guy Rees, Dinesh Selva and Yugesh Caplash
Article Type: Case Series | First Published: June 25, 2015
Orbital exenteration is a disfiguring procedure that leaves a large defect. Free flaps are increasingly widely used to fill this. We report our single centre series of free flap reconstruction, which adds to the literature base on flap choice and potential complications. Methods: A retrospective single centre consecutive case series of twenty patients who has an orbital exenteration and free flap reconstruction....
Open Access DOI:10.23937/2377-3634/1410031
The Hypoglucemic Effect of the Antioxidant Drug
C. Τsompos, C. Panoulis, K Τοutouzas, G. Ζografos and A. Papalois
Article Type: Research Article | First Published: May 04, 2015
The aim of this experimental study was to examine the effect of the antioxidant drug 'U-74389G', on rat model and particularly in an ischemia - reperfusion protocol. The beneficial effects or noneffectiveness of that molecule were studied biochemically using blood mean glucose levels. Materials and methods: 40 rats of mean weight 231.875gr were used in the study. Glucose levels were measured at 60 min of reperfusion (groups A and C) and 120 min of reperfusion (groups B and D), A and B without bu...