Open Access DOI:10.23937/2469-5793/1510006
Family Therapy in Developing Countries Primary Care
Alain Quinet, Sarah Shelmerdine, Patrick Van Dessel and Jean-Pierre Unger
Article Type: Research Article | First Published: July 23, 2015
Purpose: Mental health and psychosomatic problems are both widespread and disabling in low and middle-income countries (LMIC). There is a clear need for strategies to strengthen first line services for their treatment. Family ('systemic') therapy has been shown to be effective in this setting but there is a dearth of research investigating its use. Methods: A family therapist, psychiatrist by training was interviewed by a public health doctor specialized in health services organization, to deriv...
Open Access DOI:10.23937/2378-3672/1410012
Hemolysis of Some Elderly MDS Cases Might be Related to Prolonged Parvovirus B19 Infection
Nagahito Saito, Kiminari Ito, Katsuhiro Higashiura, Rinji Murakami, Naotaka Miyoshi, Toshiaki Nakagawa, Maneo Yamamoto, Chiko Ueno, Kenta Honma, Makio Ishikawa, Kazunori Ehata, Tomoyuki Yanami, Katsumi Katagiri and Hong Kean Ooi
Article Type: Case Report | First Published: July 27, 2015
Myelodysplastic syndrome (MDS) is a hematological disorder due to abnormal maturation and differentiation of stem cells. It is clinically manifested as cytopenia and commonly seen in elderly persons. Some MDS cases are known to show longitudinal hemolysis, which is attributed to various factors. Human parvovirus B19 (B19V) had been found in blood for transfusion and is also capable of infecting immature erythroid cells. In our study, we made a thorough review of six elderly MDS cases with slight...
Open Access DOI:10.23937/2378-2951/1410039
Ranolazine: Beyond the Treatment of Chronic Stable Angina Pectoris
Nicola Vitulano, Pio Cialdella, Massimo Gustapane, Lorenzo Vitulano, Daniela Pedicino and Gemma Pelargonio
Article Type: Review Article | First Published: July 18, 2015
The aims in the treatment of angina are relief of pain and prevention of disease progression through risk reduction. A number of patients may have contraindications or remain unrelieved from anginal discomfort with conventional drugs. Among newer alternatives, ranolazine indirectly prevents the intracellular calcium overload involved in cardiac ischemia and it is a considered as a valid addition to traditional treatments. Recent findings showed potential positive side effect of ranolazine in the...
Open Access DOI:10.23937/2469-5777/1510004
Early Stage Tibia Osteomyelitis Despite The Use of Hydroxyapatite Schanz Screws: A Case Report
Ali Cagri Tekin, Murat Cakar, Mujdat Adas, Mehmet Kursad Bayraktar, Haluk Cabuk, Ali Yuce and Yusuf Ozcan
Article Type: Case Report | First Published: July 16, 2015
In a 7-year old patient with a right cruris Grade 1 open fracture, an external fixator was applied using hydroxyapatite-covered Schanz screws. After 6 weeks the fixator and screws were removed. Two months after the removal of the fixator, the patient presented with pain in the proximal of the medial pin site and osteomyelitis was determined in the proximal right cruris. Surgical debridement was applied and from the pathology examination of material taken intraoperatively, osteomyelitis was deter...
Open Access DOI:10.23937/2572-4215.1510002
Ectopic Ventricular Activity in a Cardiac Rehabilitation Program: Significance and Prognosis
Jose Esteves da Costa, Afonso Rocha and Fernando Parada
Article Type: Short Review | First Published: August 07, 2015
Ventricular premature complexes (VPCs) are a frequent finding, even in patients without heart disease. There is an age-dependent increase in prevalence, and might be present in many structural heart diseases. VPCs are present in about 1% of routine ECGs, in up to 80% of 24-hour Holters and might be transiently present in 80 to 90% of patients after an acute myocardial infarction (AMI). The mechanisms by which they are generated include reentry, enhanced automaticity and triggered activity....
Open Access DOI:10.23937/2469-5742/1510007
Female Pelvic Organ Prolapse (POP) Surgery. Results at 24-Month Follow-Up
Rosita Aniuliene, Povilas Aniulis, Lina Slabsyte and Titas Telksnys
Article Type: Research Article | First Published: July 09, 2015
Women pelvic organ prolapse (POP) is a common pathology in urogynaecology. Given the fact that women's lifespan is increasing and society is aging, this disorder is becoming more relevant, moreover, it is embarrassing for the women involved. Literature points out that pelvic organ prolapse is common in middle age women and occurs in 50% of parous women, however, not all women require surgical intervention. Approximately, from 11 to 20% of all women may have the risk of surgical treatment for POP...
Open Access DOI:10.23937/2377-3634/1410039
Young-Onset Type 2 Diabetes - Time to Realign Clinical Priorities
Soon H Song
Article Type: Commentary | First Published: August 05, 2015
Traditionally considered as a disease of the middle-aged, type 2 diabetes (T2D) has become increasingly more prevalent in children, adolescence and young adults below the age of 40. Of concern, this evolution of young-onset T2D is a global phenomenon. Obesity is a major predisposing factor as the age of onset is inversely associated with body mass index, reflecting the consequences of sedentary lifestyle afflicting different nations and cultural backgrounds....
Open Access DOI:10.23937/2377-3634/1410038
Diabetes and Dementia
Mario Barbagallo and Ligia J. Dominguez
Article Type: Commentary | First Published: August 03, 2015
Persons with type 2 diabetes mellitus (DM2) have an increased incidence of cognitive decline and dementia. An increased cortical and subcortical atrophy has been found after controlling for vascular disease and inadequate cerebral circulation. A possible role of insulin resistance and hyperinsulinemia has been suggested to mediate the link between DM2 and Alzheimer's Disease (AD). Altered insulin signaling may contribute to AD biochemical and histopathological lesions. Both hyperglycemia and hyp...