Open Access DOI:10.23937/2377-9004/1410075

"The Association between Child Loss, Children's Paternity and High Parity in Dar Es Salaam, Tanzania": A Cross Sectional Survey at the National Referral Hospital

Andrew H. Mgaya, Hussein L. Kidanto and Hans N. Mgaya

Article Type: Research Article | First Published: February 26, 2016

A cross-sectional study conducted at Muhimbili National referral Hospital in Tanzania inquired about and compared age, socioeconomic status, perception of obstetric risks of grand multiparity, contraceptive knowledge and practice, obstetric history and having children of different paternity, between grand multiparas and lower parity women using Chi-square and student's t-tests....

 Open Access DOI:10.23937/2377-9004/1410074

A Rare Case of Mekel's Diverticulum Perforation by the Gangrenous Appendicitis during Pregnancy

Cinzia Orlandini, Nathalie Conti, Alessandra Pizzo, Elisabetta Guerrini, Luigi Verre, Felice Petraglia and Stefano Luisi

Article Type: Case Report | First Published: February 22, 2016

Meckel's diverticulum is one of the most common congenital malformations of the small intestine and it results from an incomplete obliteration of the omphalomesenteric or vitelline duct. The position of Meckel's divericulum along the length of the small intestine is variable, but is usually found within 100cm of the ileocecal valve. Perforated Meckel's diverticulum is a rare complication during pregnancy. Its presentation is similar to appendicitis and its diagnosis must be considered in all cas...

 Open Access DOI:10.23937/2377-9004/1410070

A Rare Case of Acute Pseudo-Meigs' Syndrome Presenting with Pleural Effusion and Ascites and a Ruptured Leiomyoma and Hemorrhagic Shock

Matthew Cowan, Janine Crantz, Stephanie Welsh, William Nahhas and Steven R Lindheim

Article Type: Case Report | First Published: January 28, 2016

Meigs' Syndrome is classically described as a triad of benign solid ovarian tumor with the gross appearance of a fibroma (either a fibroma, thecoma, or granulosa cell tumor) accompanied with ascites and pleural effusion. In contrast, pseudo-Meigs' Syndrome presents with ascites and pleural effusion but with any other pelvic mass, including mature teratomas, struma ovarii, and leiomyomata of the ovary, fallopian tube, or uterus....

 Open Access DOI:10.23937/2469-5726/1510032

Meta-Analysis of the Clinical Efficacy of the Placebo Effect from Tumour-Necrosis-Factor Inhibitors to Treat Rheumatoid Arthritis after Methotrexate Failure

Julie Azais, Pascale Vergne-Salle, Christine Bonnet, Carine Dufauret-Lombard, Richard Treves and Philippe Bertin

Article Type: Research Article | First Published: March 31, 2016

Tumour-necrosis-factor (TNF) inhibitors, used to treat rheumatoid arthritis (RA), have non-specific (placebo effect) and specific effects. This meta-analysis appraises these effects within the first 3 months of treatment. Data were collected from ACR 20, 50 and 70 scores at week-24 from RA patients receiving TNF-blockers or a placebo after methotrexate (MTX) failure....

 Open Access DOI:10.23937/2469-567X/1510017

The AIDS Myth at 30

Erhard Geissler

Article Type: Short Review | First Published: March 03, 2016

In 1985 the KGB and East Berlin's professor of Biology started the AIDS disinformation campaign by accusing the United States of America of having constructed and spread the AIDS agent in the course of biological weapons research. Now, 30 years later, a German authority, The Federal Commissioner for the Records of former East Germany's State Security Service, the "Stasi", is spreading disinformation regarding the alleged substantial involvement of Stasi officers in the campaign....

 Open Access DOI:10.23937/2572-4045.1510018

Pharmacological Conditioning of Brain Dead Donor Hearts with Erythropoietin and Glyceryl Trinitrate: Clinical Experience

Gayathri Kumarasinghe, Arjun Iyer, Mark Hicks, Alasdair Watson, Hong Chew, Ling Gao, Jeanette Villanueva, Andrew Jabbour, Eugene Kotlyar, Christopher S Hayward, Anne M Keogh, Emily Granger, Paul C Jansz, Kumud K Dhital, Peter S Macdonald and Phillip Spratt

Article Type: Review Article | First Published: April 01, 2016

With the increasing success of heart transplantation, older and higher-risk donors and recipients are being accepted for transplantation. The risk of primary graft dysfunction (PGD) is thus increased. We investigated a 'pharmacological conditioning' strategy, where Celsior preservation solution supplemented with glyceryl trinitrate (GTN) and erythropoietin (EPO) was used for cardioplegia and hypothermic storage, and determined graft recovery and patient survival after cardiac transplantation....

 Open Access DOI:10.23937/2378-3397/1410039

Post-cardiotomy Rescue Extracorporeal Cardiopulmonary Resuscitation in Neonates with Single Ventricle after Intractable Cardiac Arrest: Attrition after Hospital Discharge and Predictors of Outcome

Anastasios C. Polimenakos, Patrice Wojtyla, Vincent Rizzo, Chawki F. ElZein and Michel N. Ilbawi

Article Type: Research Article | First Published: March 28, 2016

Extracorporeal cardiopulmonary resuscitation (ECPR) in children with cardiac arrest refractory to conventional cardiopulmonary resuscitation (CPR) has been reported with encouraging results. We reviewed outcomes of neonates with functional single ventricle (FSV) surviving post-cardiotomy ECPR after hospital discharge....

 Open Access DOI:10.23937/2469-570X/1410026

Circulating Progenitor Cells in Regenerative Technologies: A Realistic Strategy in Bone Regeneration?

Jessica B. Chang and Justine C. Lee

Article Type: Review Article | First Published: February 26, 2016

The regeneration of bone is a complex physiological process involved in fracture healing as well as defects created by trauma, infection, tumor resection, congenital abnormalities, and impaired or insufficient regeneration. Various bone regeneration and repair strategies exist to augment surgical reconstructive procedures, including use of alloplastic and allogenic materials, distraction osteogenesis, osteoconductive scaffolds, and bone morphogenetic proteins....

 Open Access DOI:10.23937/2469-5769/1510015

Lessons Learned from Collecting Cost Data from Physicians for Economic Evaluations: Two Methods Compared

Maria Isabel Roldos and Vanessa Bustamante

Article Type: Case Study | First Published: March 18, 2016

Health care utilization databases rely on the vested commitment of patients and their families, but mainly from medical care personnel to provide information of diagnoses, procedures, and follow-up visits. Most developed countries produce health care utilization data from hospital and physician sources through large studies funded by federal research monies. In developing countries, these databases are scare....

 Open Access DOI:10.23937/2378-2951/1410073

Radial-Linear Ablation in Peri-pulmonary Vein Area Prevents Inducible Atrial Fibrillation in Dogs

Xue Zhao, Yinxiang Zhu, Xiang Mei, Jiayou Zhang, Jianqiang Hu, Wenliang Lu, Xingui Guo, Li Dai, Kailei Shi and Zhenguo Liu

Article Type: Research Article | First Published: March 16, 2016

A total of 22 dogs of both sexes (5-7 years old) were divided into two groups: 10 in control and 12 in ablation group. Multiple radial-linear lesions were created from PV orifice to peri-PV area in the dogs with CARTO guidance. The control animals went through the same procedure except ablation. AF inducibility was evaluated before and immediately after the procedure. All animals had inducible AF (100%) by atrial pacing combined with or without isoproterenol at baseline....