Open Access DOI:10.23937/2469-5823/1510060
Healthcare Provider Guidance for Breast Cancer Screening
Ray Cody Mayo
Article Type: Short Commentary | First Published: January 09, 2017
Breast cancer is the most common non-skin cancer in American women. Currently there are multiple differing recommendations regarding the appropriate approach to breast cancer screening. Unfortunately this lack of clarity causes confusion on the part of the healthcare provider and patient which may lead to suboptimal healthcare decisions. The current recommendations are reviewed and patient guidance is discussed below in a concise, organized format....
Open Access DOI:10.23937/2469-5726/1510046
Scleroderma Renal Crisis
Gioacchino Li Cavoli, Luisa Bono, Calogera Tortorici, Carlo Giammarresi, Tancredi Vincenzo Li Cavoli and Ugo Rotolo
Article Type: Case Report | First Published: February 14, 2017
Scleroderma or Systemic sclerosis is a vascular and fibrotic disease with organ-based complications and high mortality and morbidity. Renal involvement can be quite varied and scleroderma renal crisis is the most severe manifestation. We report our experience. In February 2016 a 52-year-old male was admitted to hospital with pulmonary oedema and severe arterial hypertension (240/120 mmHg)....
Open Access DOI:10.23937/2469-5726/1510044
Is There a Correlation Between DAS28/RADAI in a Cohort of Rheumatoid Arthritis Patients Treated with Biological Therapy
Hèctor Corominas, Silvia García-Diaz, Salvador Campos, Silvia Sánchez-Serrano, Silvia Iniesta, Isabel Padró, Lucinda Sanchez-Eslava, Elena Fernández-Casado, Montse Sesma, Cristina Saura, Mari Carmen Rodríguez, Maria Rusiñol and Montse Jordana
Article Type: Research Article | First Published: January 31, 2017
Rheumatoid arthritis (RA) is a chronic inflammatory heterogeneous disease presenting with acute flares, showing a prevalence of 0.5% in Spanish population according to the study EPISER and an annual incidence of 8.3 cases per 100,000 population, and that in the absence of optimal and individualized treatment causes a long-term severe disability....
Open Access DOI:10.23937/2474-3674/1510022
Cerebral Air Embolism in Commercial Flights: A Potentially Fatal Complication of Intrathoracic Lesions
Beatriz Oyanguren, Araceli Alonso-Canovas, Alicia de Felipe and Jaime Masjuan
Article Type: Case Report | First Published: February 18, 2017
Five patients with CAE were admitted to our Emergency Department (A-E). All experienced loss of consciousness (LOC). Chest radiograph showed thoracic bullae. Brain computed tomography (CT) showed subarachnoid bubbles (A), intraparenchymal bubbles (B), global hypoperfusion (C), or no abnormalities (D, E). With supportive treatment, four survived, while B died. Including ours, 18 cases of CAE during commercial flights have been reported. LOC and dyspnea were common....
Open Access DOI:10.23937/2378-3656/1410150
Dapagliflozin- Induced Severe Ketoacidosis Requiring Hemodialysis
Ossama Maadarani, Zouheir Bitar and Rashed Alhamdan
Article Type: Case Report | First Published: December 26, 2016
The availability of novel classes of medication for the treatment of type 2 Diabetes mellitus (type 2 DM) provides doctors with options to choose individualized treatments based on patient and agent characteristics beyond metformin therapy, as per current guidelines. Independent of impaired beta-cell function and insulin resistance, sodium glucose cotransporter type 2 (SGLT2) inhibitors represent a different treatment strategy for reducing plasma glucose levels and glycosylated hemoglobin concen...
Open Access DOI:10.23937/2469-570X/1410044
The C. Elegans Gscs: A Powerful Model for In Vivo Study of Adult Stem Cell Regulation
Patrick Narbonne, Abigail R Gerhold, Jean-Claude Labbe and Paul S Maddox
Article Type: Review Article | First Published: December 10, 2016
Adult stem cells hold tremendous potential for regenerative medicine. Harnessing their therapeutic benefits requires that we gain fundamental understanding of the mechanisms by which stem cells function and divide in vivo. This is hampered by the fact that stem cells often reside in compartments that remain difficult to access using imaging approaches....
Open Access DOI:10.23937/2469-570X/1410043
Central Odontogenic Fibroma of the Mandible-Revisiting Pathogenesis of Benign Tumor of the Jaw
Qilin Xu, Qunzhou Zhang, Steven Wang, Brian P Ford, Prem Pate, Lee R Carrasco, Anh D Le and Faizan Alawi
Article Type: Case Report | First Published: December 07, 2016
Central odontogenic fibroma (COF) is an uncommon benign tumor of the jaw, which clinically presents as a slow-growing neoplasm with cortical bony expansion. It has been postulated that COF might be derived from the inactive-like small nests or islands of odontogenic epithelium. However, the pathophysiology of this rare benign tumor remains largely unknown. Herein, we reported a case of simple type of COF in the mandible in a 24-year-old man who presented with progressive mandibular swelling and ...