Open Access DOI:10.23937/2469-5726/1510049
Rheumatic Disease Frequency in Hospitilized Acute Stroke Patients
Nihal Ozaras, M Serdar Sag, M Akif Sariyildiz and Sule Deveci
Article Type: Letter to the Editor | First Published: February 21, 2017
Rheumatic diseases (RD) have increased risk for stroke. We examined the records of acute stroke patients for concomitant diseases. Two of 178 patients had gout, no other RD was detected. Considering the result of our study and current evidence in the literature, we suggest that patients with gout should be monitored closely for the risk of stroke and the clinician should be aware of higher risk of stroke in these patients....
Open Access DOI:10.23937/2469-5726/1510048
SLE - Update Ethiopathogenesis Leading to Biological Therapy
J Rovensky, S Blazickova and I Stiborova
Article Type: Review Article | First Published: February 21, 2017
Systemic lupus erythematosus is a chronic, autoimmune disorder which may have even fatal consequences, particularly if it affects vital organs of the human body. It is typically manifested by inflammation of various organ systems. The course of the disease includes sporadic flare-ups, or relapses, which may lead to irreversible damage of the organs. The focus is on the suppression of clinical symptoms, inhibition of the formation of autoantibodies induce remission, preventing relapse and irrever...
Open Access DOI:10.23937/2469-5726/1510047
Glucocorticoid-Induced Leucine Zipper (Gilz) in Rheumatoid Arthritis: Relationship with Disease Activity and Steroid Use
Laura E Eades, Angeline S Thiagarajah, Sarah A Jones, Huapeng Fan, Anastasios Nalpantidis, Eric F Morand and Michelle Leech
Article Type: Research Article | First Published: February 21, 2017
Clinical data was obtained from RA patients and medical records. Three control cohorts were also recruited, including 23 healthy controls, 25 patients with fibromyalgia and 44 patients with depression. Blood was taken from each participant. Following isolation of peripheral blood mononuclear cells (PBMC) from whole blood, RNA was extracted. Reverse transcription polymerase chain reaction (RT PCR) and quantitative real time PCR (qPCR) were performed to quantify GILZ expression....
Open Access DOI:10.23937/2572-3278.1510020
Biogenic Amine Formation in Reformulated Cooked Sausage Without Added Nitrite
Claudia Ruiz-Capillas, Ana M Herrero, Mehdi Triki and Francisco Jimenez-Colmenero
Article Type: Original Article | First Published: February 23, 2017
The purpose of this study was to assess the formation of biogenic amines (BA) during chilled storage (60 days) in cooked sausages made without added nitrite. Various combinations of ingredients celery, sodium lactate, carmine, orange dietary fibre and vitamins C and E - were used as substitutes for nitrite. BA levels were low irrespective of formulation, the largest variations between products were found in the case of cadaverine. ...
Open Access DOI:10.23937/2572-3243.1510031
Treatment of Sports-Related Injured Knee with Incidental Extra-articular Giant Cell Tumor of the Pes Anserinus Tendon Sheath
Sungwook Choi, Younghee Maeng, Kyungryeol Lee and Donghee Kim
Article Type: Case Report | First Published: February 13, 2017
We report a case of a 21-year-old male with knee injury with a giant cell tumor of the tendon sheath resulting in a pes anserinus. As seen in this case, in a sports-related knee injury with an associated giant cell tumor, an initial treatment of the mass was performed first. After the confirmation of non-recurrence after 1 year follow up, the treatment of the sports related injury was followed. In any type of knee injury associated with giant cell tumor, initial treatment of the mass followed by...
Open Access DOI:10.23937/2474-3690/1510023
Cardiac Fibrosis in Hypertension
Tracey Keteepe-Arachi and Sanjay Sharma
Article Type: Review Article | First Published: February 14, 2017
Myocardial fibrosis is the hallmark of myocardial remodelling found in hypertensive individuals. This process adversely affects the outcomes of such patients and results in diastolic and systolic cardiac dysfunction, electrical dysrhythmia and potentially sudden death. Collagen metabolism has been highlighted as the primary mechanism by which fibrosis is regulated. However, there are many other facets to the pathophysiology of myocardial fibrosis including mechanical, cellular and hormonal influ...
Open Access DOI:10.23937/2469-5793/1510052
Eighty-Eight Year-Old Demented Woman Lives Alone Independently: A Case Report
Koh Iwasaki and Shin Takayama
Article Type: Case Report | First Published: February 28, 2017
The care team discussed the reason of her independence and the plan on how to provide care for her. We concluded that she was independently capable of living in her own home in her small, very familiar community. She has three close, familiar friends nearby to frequently chat and drink tea with. Situated near the city of Ishinomaki - which was destroyed by the great tsunami in 2011 - her small community is safely located far from the city center and on a hilltop....
Open Access DOI:10.23937/2469-5750/1510042
A Case of Generalized Lichenoid Reaction upon Red Permanent Lip-Liner Make-Up
Perruchoud DL, Kiermeir DM, Adatto MA, Lam MC, Borradori L and Simon D
Article Type: Case Report | First Published: February 18, 2017
Tattoo reactions are most commonly associated with red inkdue to the presence of mercury and its sulphides. However, nowadays most allergic reactions to red tattoo are triggered by organic pigments such as Pigment Red 181 (CI 73360) and Pigment Red 170 rather than the traditional mercury sulphides. The use of red pigments containing mercury may result in lichenoid reactions and other localized side reactions....
Open Access DOI:10.23937/2469-584X/1510042
Acute Appendicitis in Pediatric Patients: An Updated Narrative Review
Abigail B Podany, Anthony Y Tsai and Peter W Dillon
Article Type: Review Article | First Published: February 21, 2017
Acute appendicitis is the most common pediatric surgical emergency worldwide. The diagnosis and management in children involves a unique set of challenges for clinicians. While the diagnosis is primarily clinical, utilization of imaging and laboratory studies can aid practitioners in making a more prompt diagnosis, preventing complications from appendiceal perforation and limiting the rate of negative appendectomies. In children special emphasis has been placed on minimizing ionizing radiation e...
Open Access DOI:10.23937/2474-1353/1510045
Survey of Breast Cancer Incidence in the Middle East and the United States
Barbara G Silverman, Hoda Anton-Culver, Freddie Bray, Stevens Lisa, Eser Sultan, Nimri Omar, Pavlos Pavlou, Kevin Ward, Haris Charalambous, Anna Demetriou, Argyrios Ziogas, Ariana Znaor, Lital Keinan-Boker and Chang Jenny
Article Type: Research Article | First Published: February 20, 2017
Breast cancer is the most frequent cancer and the leading cause of cancer deaths in women worldwide. Regional comparisons of breast cancer incidence can shed light on population and health care factors that contribute to differences between countries. We surveyed breast cancer incidence in four population based cancer registries in the Middle East to identify factors associated with regional variations in breast cancer incidence....