Open Access DOI:10.23937/rmi-2017/1710002

Does Luteal Phase Deficiency Exist and What is its Association with Infertility?

Monica S Chung, Laurice Bou Nemer and Bruce R Carr

Article Type: Mini Review | First Published: June 06, 2018

Luteal Phase Deficiency (LPD), also known as luteal phase defect, is a concept that was defined by Georgeanna Seegar Jones in 1949 as reduced progesterone production by the Corpus Luteum (CL). LPD results from low endogenous progesterone production and the resultant insufficiency to maintain a secretory endometrium to allow embryo implantation and growth....

 Open Access DOI:10.23937/2572-4193.1510042

Omalizumab: Pharmacological Properties, Primary Therapeutic Effect Mechanisms and Adverse Effects

Oner Ozdemir

Article Type: Review Article | First Published: June 07, 2018

Since it was approved in 2003 by the FDA for the therapy of adult and adolescent moderate-severe persistent uncontrolled allergic asthma, the studies on asthma patients have demonstrated that omalizumab has an encouraging safety report, regardless of the allergic sensitization type. Omalizumab was later tried in the therapy of other Th2-type allergic disorders e.g. allergic asthma. Omalizumab hinders IgE effector functions by preventing IgE joining to high-affinity IgE receptors (FcεRI) on effe...

 Open Access DOI:10.23937/2469-5793/1510076

Association between Health Self Efficacy and African American Male Inmates Prior Substance Use Treatment History: Implications for STI Risk Reduction

Torrance Stephens, Ta-Kenda Holmes and Aniya Allen

Article Type: Research Article | First Published: June 07, 2018

African American men are disproportionately represented in the U.S. correctional system; evince exceptionally high rates of infectious diseases such as HIV/AIDS and like many inmate populations, problem behaviors associated with drug and alcohol use. According to the US Bureau of Justice Statistics (BJS) in in 2013 there were 2,220,300 adults incarcerated in US federal and state prisons, and county jails with 4,751,400 adults in 2013 being on probation or on parole....

 Open Access DOI:10.23937/2469-5750/1510054

Erythema and Acute Pain in the Hands

Chelsea Tagaqa, John DiGiovanni, and Suzanne Wolf

Article Type: Case Report | First Published: June 07, 2018

A 21-year-old active duty soldier presented with skin lesions distributed on his face, arms, and hands. Two weeks prior to presentation he characterizes the development of lower lip herpetic lesion. He was otherwise well. Three days prior to presentation he was given Valtrex 1000 mg BID. He describes expressing fluid from lesions located bilaterally on his mandibular surface....

 Open Access DOI:10.23937/2469-567X/1510039

Prevalence of Haematological and Serum Biochemical Abnormalities in HIV Infected Patients in Ghana, Before and after Antiretroviral Therapy

Samuel Kwadwo Afari and Emmanuel Awusah Blay

Article Type: Research Article | First Published: June 07, 2018

Highly Active Antiretroviral Therapy (HAART) has led to prolonged survival of HIV-infected patients. However, the long-term use of HAART has the potential to cause haematological and biochemical abnormalities such as cytopenia, liver damage and renal injuries, which may be life threatening....

 Open Access DOI:10.23937/2378-3397/1410079

When a Case of Ulcerative Colitis Requires Mucosectomy and Hand-Sewn Ileo-Anal Pouch Anastomosis

Mary Teresa MO Donnell, Joshua IS Bleier and Gary Wind

Article Type: Case Report | First Published: June 07, 2018

Treatment of ulcerative colitis with total proctocolectomy and ileal pouch anal anastomosis (IPAA) provides a near cure for the bowel component of ulcerative colitis, a restoration of bowel continuity, and the possibility of normal defecation behaviors for patients. ...

 Open Access DOI:10.23937/2572-4215.1510014

The Role of Early Mobilization in the Intensive Care

Ana Zao

Article Type: Research Article | First Published: June 07, 2018

Amyotrophy, muscle strength deficit, sarcopenia, pain, contractures and osteoporosis are some of the musculoskeletal complications frequently observed in critically ill patients. However, the negative effects of immobility are rarely limited to a single system....

 Open Access DOI:10.23937/2469-5734/1510053

Radix Paramolaris in a Second Mandibular Molar: A Case Report of an Unusual Finding

Marta Alonso, Oliver Valencia de Pablo, Roberto Estevez, Jorge Vera and Rafael Cisneros

Article Type: Case Report | First Published: June 07, 2018

Chemomechanical preparation of the root canal system is extremely important during root canal therapy and, in order to achieve this goal, location of all entrances into the root canal system must be accomplished. The mandibular second molar usually has two roots and three root canals; However, there can be variations both in the number of roots as well as in the number of canals. ...

 Open Access DOI:10.23937/ijfa-2017/1710007

A Case Study on Antibiotic Loaded Calcium Sulphate Beads in the Management of Diabetic Foot Complications

Rajesh Kesavan, Changam Sheela Sasikumar and Vimalkumar Ramachandran

Article Type: Case Report | First Published: June 07, 2018

A 62-year-old Female patient with Type 2 diabetes (Hb A1 C > 7) of 12 years duration with controlled hypertension and was referred to our Hycare Wound Care Centre for immediate assessment due to a limb threatening foot infection. The diabetologist had counselled the patient with regards to the likelihood of amputation....

 Open Access DOI:10.23937/2572-3308.1510027

Mastocytosis: A New Therapeutic Scenario with Omalizumab

Anna Zampetti

Article Type: Short Communication | First Published: June 07, 2018

In pediatric population, it manifests with isolated skin mastocytoma, a red brown papule and nodule that may urticate (Darier's sign) or with multiple and diffuse similar lesions as observed in urticaria pigmentosa. Both condition usually remains localized to the skin and spontaneously regresses with age. In infants less than 3 year, it is also described a rare diffuse cutaneous mastocytosis with erythrodermia and bullous lesions....