Open Access DOI:10.23937/2474-3674/1510057

Incidence of Venous Thromboembolism in Asian Trauma Patients - An Asian Trauma Centre Review

Wee Ming Tay, TS Go and LT Teo

Article Type: Research Article | First Published: November 24, 2018

To evaluate the incidence of venous thromboembolism (VTE) in Asian trauma patients and the relation to use of chemoprophylaxis with low molecular weight heparin (LMWH). The Tan Tock Seng trauma database between December 2011 and December 2012 was reviewed. All trauma patients with an injury severity score of 9 or more were included. All medical records were screened for Duplex ultrasound (US) of lower limbs, any computed tomography pulmonary angiogram (CTPA) performed and whether there was use o...

 Open Access DOI:10.23937/2469-5742/1510049

Female Hypospadias and Urinary Incontinence: Surgical Solution of a Little-Known Entity

Mario Lima, Niel Di Salvo, Tommaso Gargano and Giovanni Ruggeri

Article Type: Case Report | First Published: November 23, 2018

We describe the case of a female patient referred to our Institution for urinary incontinence likely due to hypospadias. As a matter of fact, her clinical history was way more complex. She was born at term, with no prenatal diagnostic suspicions. After toilet training achievement, between 2 and 3 years old, her mother noticed a continuous urinary dripping during day and night hours. Simultaneously, she started suffering from well-documented recurrent urinary tract infections (UTIs). She was firs...

 Open Access DOI:10.23937/iaoms-2017/1710015

Association between Intra-Articular Corticosteroid Injection and Temporomandibular Joint Structure Changes

Atef A Fouda

Article Type: Research Article | First Published: November 23, 2018

Thirty-six female adult Wistar albino rats divided into three groups according to the number of corticosteroid injection, each group has two subgroups according to the time of scarification either after one week or two weeks after the last injection. The most affected structure of the temporomandibular joint is condylar head and temporal bone, followed by hyaline cartilage and the fibrous layer. The articular disc and retro-discal tissue are the last structure to be affected with intra-articula...

 Open Access DOI:10.23937/2469-5823/1510108

Impact on Caregivers of Patients with Myeloproliferative Neoplasms (MPNs) in the United States: Results from the Living with MPNs Survey

Dilan Paranagama, Shreekant Parasuraman, Jingbo Yu, Lindsey Lyle and Ruben Mesa

Article Type: Original Article | First Published: November 23, 2018

904 patients with MPNs aged 18-70 years in the US who completed the online Living with MPNs survey between April and November, 2016. The MPN Symptom Assessment Form Total Symptom Score was used to describe symptom burden. Patient-reported need for caregiver assistance and caregivers' employment change due to MPNs was reported. Most survey respondents to this US survey reported receiving MPN-related caregiver assistance. A higher symptom burden was reported by those receiving assistance than thos...

 Open Access DOI:10.23937/2378-3516/1410097

Correlation between Pentraxin-3 and Left Ventricular Diastolic Dysfunction in Obstructive Sleep Apnea

Jie-Ru Li, Xiu-Hua Gao, Ju-Qiang Han, Wen-Yan Luo and En-Sheng Ji

Article Type: Original Article | First Published: November 23, 2018

Obstructive sleep apnea (OSA) is one of independent dangerous factors for cardiovascular disease including heart failure. Recent studies demonstrated that left ventricular diastolic dysfunction (LVDD) and pentraxin-3 (PTX-3) are early signs for development of heart failure. The objective of our study was to estimate the relation between OSA severity and LVDD and PTX-3. Sixty-six OSA patients and 25 healthy people who underwent polysomnography to diagnose OSA were enrolled. Ninety-one participant...

 Open Access DOI:10.23937/2378-3648/1410040

HLA DRB1*/DQA1*Alleles and TNF-alpha G308A Polymorphism Protect against Neuromyelitis Optica in the Cuban Population

Fernandez-de-Cossio ME, Cintado A, Nazabal M, Camacho H, Diaz T, Villarreal A, Ale M, Grass D, Cervantes-Llanos M, Pavon-Fuentes N, Benitez JV, Cabrera-Gomez JA, Diaz de la Fe A and Penton-Rol G

Article Type: Research Article | First Published: November 23, 2018

Neuromyelitis optica (NMO) is a complex immune-mediated disease whose prevalence differs among ethnic groups, most likely due to genetic factors. The presence of the Human Leucocyte Antigens (HLA) extended haplotype is a risk for NMO. The tumor necrosis factor-alpha (TNF-a) is believed to play a role in NMO pathogenesis. Although single nucleotide polymorphisms (SNPs) in the TNF-a promoter region (pTNF-a) has been shown to influence levels of TNF-a production, such an association is not evident ...

 Open Access DOI:10.23937/2572-4037.1510036

A Critical Review and Future Directions for Research: Personality and Social Entrepreneurial Success

Shilpi Sharma and Sahni SP

Article Type: Review Article | First Published: November 23, 2018

Probably millions of people across the world dream of starting their own business, a fraction of them may gather the courage and resources to pursue their ambitions, and still, even a smaller fraction of those may persevere through the challenges and inevitable disappointments, entrepreneurial process may present; and finally, a very small number of entrepreneurs succeed in achieving their objectives. What determines the difference in behaviours and attitudes of these individuals? Why some never...

 Open Access DOI:10.23937/ijfa-2017/1710019

Total Ankle Replacement: Indications, Rehabilitation and Results

Marco Massobrio, Giovanni Pellicano, Valter Santilli and Lucrezia Tognolo

Article Type: Research Article | First Published: November 22, 2018

Even though fusion is the main form of treatment for end-stage osteoarthritis (OA) of the ankle, total ankle replacement (TAR) is increasingly being recognized as an effective alternative procedure, with favorable clinical results and improved quality of life. However, the results have been disappointing compared to those of hip and knee arthroplasty. In fact, the ankle is a more complex joint and its biomechanics and kinematics are strongly influenced by neighboring joints. The ankle joint comp...

 Open Access DOI:10.23937/2572-4215.1510015

Fractional Anisotropy Brain Changes in Spasticity after Peripheral Injections of Botulin

Miguel Angel Bertoni, Mohammed Sakel and Ali Hojjatoleslami

Article Type: Research Article | First Published: November 22, 2018

Seven subjects with spasticity that developed 2-22 years after cerebrovascular accidents (CVA) were studied with 3T MRI of the brain including diffusion tractography (DTI) and fractional anisotropy (FA) measurements of the white matter of the corticospinal tracts (CST), corpus callosum (CC) and cerebral lobes of the affected and contralateral sides prior and after the injection of botulin toxin at the contours of peripheral nerves of the affected side....

 Open Access DOI:10.23937/2469-5866/1410025

Cognitive Rehabilitation Improves Performance of Individuals with Mild to Moderate Traumatic Brain Injury: A Review of Comprehensive Neuropsychological Services as a Model Approach

Cheryl A Frye, Anton Hardy and Maria Lifrak

Article Type: Review Article | First Published: November 22, 2018

Traumatic Brain Injuries (TBI) can result in physical, cognitive and emotional symptoms and the constellation of sequelae that can linger for years and is termed post-concussion syndrome (PCS). For these ailments, therapy is available to help individuals recover; however, it is controversial whether cognitive rehabilitation can improve or forestall lost or damaged abilities. It is important to clarify this because insurances companies can be reluctant to pay for this treatment. To test the effic...