Open Access DOI:10.23937/2572-4045.1510037
Surgical Site Infection after Liver Transplantation: Single-Center Experience
Kenneth A Softness, Ahmed ElSabbagh, Alexander Kroemer, Jason Hawksworth, Cal S Matsumoto, Thomas Fishbein and Raffaele Girlanda
Article Type: Research Article | First Published: November 26, 2018
Infections are frequent complications after liver transplantation. The impact of surgical site infections on patient outcome remains unclear. The aim of our retrospective study is to analyze the incidence and predictors of surgical site infections after liver transplant at our program and to determine their impact on patient outcome. Twenty-four (9.5%) surgical site infections were recorded among 252 liver transplants performed between January 2011 and December 2013. Among perioperative variable...
Open Access DOI:10.23937/2474-3658/1510060
Tigecycline Induced Cholestatic Liver Injury: A Case Report
Jing Liang, Kai Zhao, Liqin Zhu and Yihe Liu
Article Type: Case Report | First Published: November 26, 2018
A 41-year-old female patient received tigecycline because of abdominal infection caused by carbapenem-resistant klebsiella pneumoniae (CRKP) after performing cholangiolithotomy by the endoscopic retrograde cholangio-pancreatography (ERCP). Subsequently she developed cholestatic liver injury as substantiated by increased alkaline phosphatase (ALP) and bilirubin. Tigecycline was switched to dual carbapenems. Her liver function tests improved. We suggest that bilirubin levels should be cared in pat...
Open Access DOI:10.23937/2469-5823/1510110
Cognitive Impairment and Associated Factors in Patients Hospitalized in Neurology Services
Emel Bahadir-Yilmaz and Elvan E ATA
Article Type: Original Article | First Published: November 26, 2018
Cognitive impairments commonly occur due to neurological diseases and elderly. Cognitive impairments in many elderly patients is thought to be related only to neurological disease. However, it is necessary to investigate whether this impairment is due to age. Because cognitive impairment may adversely affect the treatment and care needs of elderly patients; therefore, it is important to assess their cognitive functions. This was a descriptive study conducted to identify cognitive impairment and ...
Open Access DOI:10.23937/2378-3664/1410025
Folate Targeted Galactomannan Coated Iron Oxide Nanoparticles as a Nanocarrier for Targeted Drug Delivery of Capecitabine
Subha Veeramani, Kirubanandan Shanmugam and Renganathan Sahadevan
Article Type: Research Article | First Published: November 22, 2018
Iron oxide nanoparticle is the most promising nanoparticles (NPs) capable in Drug Delivery and targeting. Iron oxide nanoparticles were synthesized by green synthesis. Galactomannan, when attached to the surface of the nanoparticles, increases the biocompatibility of the nanoparticles. Folic acid (FA) is used as the ligand to target folate receptors, which are found abundant in cancer cells. FeNPs-GM-FA could target cancer cells when used as drug carriers. The synthesized iron oxide nanoparticle...
Open Access DOI:10.23937/2378-3516/1410098
A Comparison between Two Pathophysiologically Different yet Microbiologically Similar Lung Diseases: Cystic Fibrosis and Chronic Obstructive Pulmonary Disease
Daniel E Fenker, Cameron T McDaniel, Warunya Panmanee, Ralph J Panos, Eric J Sorscher, Carleen Sabusap, John P Clancy and Daniel J Hassett
Article Type: Review Article | First Published: November 29, 2018
Cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are chronic pulmonary diseases that affect ~70,000 and 251 million individuals worldwide, respectively. Although these two diseases have distinctly different pathophysiologies, both cause chronic respiratory insufficiency that erodes quality of life and causes significant morbidity and eventually death. In both CF and COPD, the respiratory microbiome plays a major contributing role in disease progression and morbidity. Pulmona...
Open Access DOI:10.23937/2378-3397/1410090
Percutaneous Treatment of Endoscopic Sphincterotomy-Related Duodenal Perforation
Bayrak Mehmet and Altıntas Yasemin
Article Type: Case Report | First Published: November 26, 2018
Duodenal perforation due to endoscopic sphincterotomy is an uncommon but occasionally fatal complication. This serious complication has been traditionally treated by immediate surgical exploration when digestive fluid leakage occurs. Herein, we will present the percutaneous treatments of an endoscopic sphincterotomy-related duodenal perforation and perforation-related retroperitoneal abscess by using percutaneous drainage techniques. An 8-F internal-external biliary drainage catheter provided me...
Open Access DOI:10.23937/2378-3397/1410089
Inflammatory Pseudotumor in an Irreducible Inguinal Hernia
Edwina Ayaaba Ayabilah, Richmond Hagan, Martin Morna and Jacob A Akoh
Article Type: Case Report | First Published: November 26, 2018
A 64-year-old man presented with a 2 year history of reducible groin swelling which had progressively increased in size. The swelling had become irreducible 3 months prior to admission but apart from loss of weight, there were no other associated symptoms. He was anaemic (Hb 11 g/dL). At operation, a large, hard left inguinoscrotal hernia was encountered. This raised the suspicion of a tumour and therefore the testis and large mass were mobilised and resected along with an adherent segment of sm...
Open Access DOI:10.23937/2469-5734/1510072
Fibrous Dysplasia in Maxillary Bone: Case Report
Marcelo Domingues Pinto, Gustavo Gaffree Braz, Roberto Gomes Santos, Diego Polido, Jonathan Rodopiano Paixao and Hugo Sole de Melo
Article Type: Case Report | First Published: November 26, 2018
Fibrous dysplasia is a benign lesion, congenital, recurrent character and etiology unknown, caused by a bone modeling disorder with constant alterations of the normal bone being replaced by immature fibrous tissue. The lesion may involve one or more bones being the maxilla the facial bone more affected. We report a case of polyostotic fibrous dysplasia in a male patient complaining of increased volume in the right genital region. In this case, Computed Tomography (CT) was the main radiographic e...