Open Access DOI:10.23937/2643-3966/1710022
Cardiac Interventions in Symptomatic Patients ≥ 90-Years-Old (Nonagenarians): A Single-Center Retrospective Analysis of Spectrum and Outcome
Philippe N Muller, Christine H Attenhofer Jost, MD, Osmund Bertel, MD, Barbara Naegeli, MD, Edwin Straumann, MD, Pierre Levis, MD, Burkhardt Seifert, Dominik Maurer, MD, Christoph Scharf, MD, Olaf Franzen, MD and Franz Wolfgang Amann, MD
Article Type: Research Article | First Published: August 28, 2019
The database at our center from 2005-2014 was searched for all percutaneous cardiac procedures, including coronary angiography with or without percutaneous coronary intervention (PCI), transcatheter aortic valve replacement (TAVR), percutaneous mitral valve repair by MitraClip (PMVR), balloon valvuloplasty of the aortic valve (ABVP) and radiofrequency ablation (RFA). Age at procedure, clinical data, type and findings at procedure, in-hospital outcome, survival and predictors for survival were an...
Open Access DOI:10.23937/2643-3966/1710021
Case Report: A 13 Years Old Boy with Danon Disease, and Intellectual Disability
Alawni O, Almusaad A and Eyaid W
Article Type: Case Report | First Published: August 26, 2019
A 13-years-old boy. He was born at home at 30 weeks of gestation. He stayed in nursery for 3 months. He sat independently at the age of one year, walked at around 3 years and started to run around 4 years of age. Currently, he can walk, and run well. He wears his clothes, button, and unbutton his shirts. He copies letters, scripts and shapes however; he usually does not follow lines. He spoke at the age of 2 years it was single words like mama and dada....
Open Access DOI:10.23937/2643-3966/1710020
Left Ventricular Hypertrophy in a Patient with AL Amyloidosis: A Rare Overlap of Two Cardiomyopathies
Brock M, Sanchorawala V, Berk JL, Cui H, Gopal DM, O'Hara C, Ruberg FL and Siddiqi OK
Article Type: Case Report | First Published: August 26, 2019
A 62-year-old woman with newly diagnosed systemic AL amyloidosis was evaluated for severely increased left ventricular (LV) wall thickness. Her echocardiographic, cardiac MRI, and genetic findings led to a diagnosis of hypertrophic cardiomyopathy (HCM). Five years after achieving relative a partial hematologic response with chemotherapy, the patient died after developing rapidly progressive heart failure and cardiogenic shock. A full autopsy diagnosed both cardiac amyloidosis and HCM. The overla...
Open Access DOI:10.23937/2572-3987.1510020
Oncolytic Viruses and Their Application to Cancer Treatment
Xie FZ and Zheng LL
Article Type: Research Article | First Published: August 24, 2019
Early in the 20th Century, a case was reported in The Lancet, that a notable decline in abnormal leucocyte of a female chronic-leukemia suffer was seen, and resulted in her unexpectedly improved condition, after her accidental infection of influenza virus. In 1912, Italian doctor Deface found that tumors of patients with cervical cancer would spontaneously shrink or regress if inoculated attenuated rabies vaccines. And this has raised the curtain on oncolytic virus therapy for tumors. Several mo...
Open Access DOI:10.23937/2378-3656/1410286
What are the Factors and the Method Used for the Formation of Nasal Septal Perforations due to Septoplasty?
Erkan YILDIZ
Article Type: Original Article | First Published: September 14, 2019
There were 280 male and 120 female patients. 378 patients had no postoperative septal perforation. 22 had perforation after surgery. Of the patients in the perforated group, 19 male and 3 female were female. 21 of these patients smoked, 1 patient did not drink. 11 of these patients were drinking alcohol and 10 of them did not drink alcohol. Transseptal suturation + nasal saturation splint was used in 14 patients to stabilize the septum while perforation rate was 22/400 (1.3%). Male sex ratio was...
Open Access DOI:10.23937/2378-3656/1410285
Effect of Chemical Irrigants on the Bond Strength of a Universal Adhesive System to Dentin-Enamel Junction and Different Dentin Regions
Alper KAPTAN, DDS, PhD., Vahti Kilic, DDS, PhD., Feridun HURMUZLU, DDS, PhD., Ahmet Serper, DDS, PhD. and Arife KAPTAN, DDS, PhD.
Article Type: Research Article | First Published: September 11, 2019
The purpose of this in vitro study was to evaluate the influence of different irrigation solutions on the microshear bond strength of a universal adhesive system applied in etch & rinse mode and self-etch mode to dentin- enamel junction (DEJ), coronal dentin, pulp chamber dentin, and floor of the pulp. As well as a highly adequate apical seal, an effective coronal seal, is one of the primary goals of a successful endodontic dental treatment. Recently, a large number of adhesive systems have been...
Open Access DOI:10.23937/2378-3656/1410284
Atypical Presentation of Viral Myocarditis in a Young Adult
Mandeep Kaur, Prema Bezwada and Ayala Rodriguez Cesar
Article Type: Case Report | First Published: September 09, 2019
Convulsive Syncope can be difficult to distinguish from seizures at times. We present a young adult with cardiogenic convulsive syncope that mimic seizures. Continuous cardiac monitoring revealed various arrythmias during seizure like activity. She had a viral prodrome. Cardiac MRI was diagnostic for myocarditis. More detailed studies for the role of a noninvasive cardiac testing such as Cardiac MRI (CMR) and newer treatment modalities such as anti-thymocyte immunoglobulin are required for the m...
Open Access DOI:10.23937/2378-3656/1410282
Chronic Wound Formation on an Old Burn Scar after Surgical Incision and Hyperbaric Oxygen Therapy: Case Report
Kubra Ozgok-Kangal, Iclal Karatop-Cesur, Cesur Ustunel and Kemal Simsek
Article Type: Case Report | First Published: September 04, 2019
Chronic wounds fail to progress through the phases of wound healing; inflammation-proliferation-remodelling which are usually the result of persistent infection, malperfusion due to periwound hypoxia, cellular failure, and unrelieved pressure or repetitive trauma. In this report, we present a different rare cause of a chronic wound; a surgical incision on a post-burn scar during the surgery of transurethral resection of the prostate (TUR-P) because of urethral stricture. After six weeks, the sur...
Open Access DOI:10.23937/2378-3656/1410281
A Novel Use of Liraglutide: Induction of Partial Remission in Ulcerative Colitis and Ankylosing Spondylitis
Jeffrey Lourie
Article Type: Case Report | First Published: August 29, 2019
Ulcerative colitis and ankylosing spondylitis treatment options are limited to a few classes of medications at this time. Those options provide improvement for some patients, but leaves many with ongoing, unremitting symptoms. We report a case of ulcerative colitis (UC) with comorbid ankylosing spondylitis (AS), in which administration of a daily subcutaneous liraglutide, an exogenous Glucagon-like Peptide-1 receptor agonist (GLP-1RA), led to symptomatic remission of UC and significant improveme...