Open Access DOI:10.23937/2572-3243.1510076
Medical Care Delivery during the World Triathlon Age Group Short Course Championship
Jeffrey S Shilt, MD, Lawrence P Lai, MD, MS, John Georgy, MD, MBA and Indranil Kushare, MD
Article Type: Original Article | First Published: May 08, 2020
Providing medical care in the days leading up to an event for age group athletes in endurance sports can be challenging in large participant events. Little direction is provided in the medical literature to help prepare one for this task. The objective of the report is to describe our experiences with delivery of care to the United States athletes’ preceding and immediately after an International Triathlon Union (ITU) World Triathlon Age Group Championship. This report can guide preparation by...
Open Access DOI:10.23937/2474-3658/1510122
Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) Used in the Management of Lemierre's Syndrome
Marcus Taylor, MRCS, Denish Apparau, MRCS and Kandadai Rammohan, FRCS-CTh
Article Type: Case Report | First Published: May 14, 2020
A 21-year-old female presented with non-specific symptoms of cough and sore throat. She rapidly became profoundly unwell, requiring intubation and ventilation. Clinical and radiological appearances were felt to be in keeping with Lemierre’s Syndrome (LS). The diagnosis of LS was confirmed when pleural fluid samples were found to contain Prevotella veroralis and Fusobacterium necrophorum. Due to worsening respiratory function the patient was commenced on veno- venous extracorporeal membrane oxy...
Open Access DOI:10.23937/2474-3658/1510119
Past, Present and Future of Pandemics (COVID-19)
Mzee Said Abdulrahman Salim and Muslimat Kehinde Adebisi
Article Type: Review Article | First Published: April 30, 2020
From herpes and legionnaires' disease in the 1970s to AIDS, Ebola, the severe acute and respiratory syndrome (SARS), contagious diseases continue to threaten and disrupt human societies. The end of last year (2019) doctors in Hubei province encountered patients with flu-like symptoms that are similar in characteristics to SARs having consistent aetiologies unfamiliar to them but with a possible link to their prior knowledge. A virus outbreak which has a genomic sequence similar to that of β vir...
Open Access DOI:10.23937/2378-3648/1410049
Ancestral European Origins and Population Structure of Helicobacter pylori Strains from an Iranian Population
Masoud Keikha
Article Type: Editorial | First Published: May 13, 2020
Helicobacter pylori is a spiral, microaerophilic and motile bacterium originated by its polar flagella that is the etiological reason of chronic gastritis, peptic ulcer, gastric cancer, and extra-gastrointestinal diseases. The human stomach is considered the only host of this bacterium. This bacterium has been residing in the human stomach for many years and has been coevolved simultaneously with its host, especially since the horizontally transmitted condition is not observed in Helicobacter py...
Open Access DOI:10.23937/2378-3648/1410048
Which Aligner Software is the Best for Our Study?
Abolfazl Bahrami
Article Type: Short Report | First Published: May 13, 2020
Alignment is the first step in most RNA-seq analysis pipelines, and the accuracy of downstream analyses depends heavily on it. Many algorithms have been developed for this alignment step. Due to the increasing growth in the use of aligning and mapping software, this software has become particularly important. This seemingly worthless issue but it is confusing and difficult to compare results from different approaches. We performed a comprehensive benchmarking of 4 popular and common aligners and...
Open Access DOI:10.23937/2469-5750/1510081
Linear Iga Bullous Dermatosis in Crohn's Disease: A Case Report
Ruba Ibrahim, MD, Gil Armoni, MD, Georgina-Maria Sarika, MD and Vered Molho-Pessach, MD
Article Type: Case Report | First Published: May 20, 2020
Linear IgA bullous dermatosis (LABD) is a rare autoimmune, vesiculo-bullous skin disease. It has been previously reported in association with inflammatory bowel disease, particularly ulcerative colitis. We report a case of LABD in a patient suffering from Crohn's disease who received tumor necrosis factor-α inhibitor therapy and developed LABD several months later. Linear IgA bullous dermatosis (LABD) is a rare autoimmune, vesiculobullous skin disease, characterized by linear deposition of IgA ...
Open Access DOI:10.23937/2469-5750/1510080
Bowen's Disease in the Thenar Eminence: A Case Report
Rafaela Pais Serras, Marta Duarte, Maria Manuel Mendes and Maria Manuel Mouzinho
Article Type: Case Report | First Published: May 01, 2020
Bowen's disease is a squamous cell carcinoma in situ that can degenerate into an invasive squamous cell carcinoma. Early diagnosis and treatment are crucial. There are several therapeutic options available but the most successful is surgical excision with a safety margin. We present a case report of an atypical Bowen's disease in an uncommon location, for which was performed surgical excision with 1 cm of safety margin and then the secondary defect was covered by a skin graft. No complications w...
Open Access DOI:10.23937/2643-461X/1710031
SARS-Cov-2 Infection and Cardiology: Beware of Myocarditis
Marco Antonio Machado Schlindwein, Leticia Caroline Breis, Isabelle Pastor Bandeira, Rafael M Ronsoni, MD, MsC, Clizenaldo Torres, MD and Marcus Vinicius Magno Goncalves, MD, PhD
Article Type: Commentary | First Published: May 13, 2020
The emergence of SARS-CoV-2 is a challenge in the actual medical scenario. Besides the classical lung and respiratory disease, patients infected with the virus can present with cardiac injury, and pathogenic mechanisms point to direct infection of the heart. In this paper, we seek to show the correlation between cardiology and SARS-CoV-2 infection, especially with regard to myocarditis, which has been shown to be one of the complications in COVID-19. SARS-CoV-2 is the virus responsible for coron...
Open Access DOI:10.23937/2643-461X/1710030
Parasites Intestinal: Level of Knowledge and Envisions Measures Mothers of Schoolchildren of Marianao Municipality
Osvaldo Batista Rojas, MSc
Article Type: Research Article | First Published: April 24, 2020
To determine the association between the level of knowledge about intestinal parasitosis and preventive measures in mothers of parasitized schoolchildren between the ages of 5 and 11 years of the Marianao municipality in Havana in 2019. An observational, analytical, crosssectional study that included 195 mothers of schoolchildren between the ages of 5 and 11 years attended in the four Family Medical Offices of Marianao, Havana. Age, marital status, educational level, occupation, level of knowled...
Open Access DOI:10.23937/2378-3397/1410110
Evaluation of Intra-Operative Ultrasound in Assessing Clear Margin in Breast Conservative Surgery
Ahmed Shalaby, Matei Dordea, Marwa Badawi, Ashwin Rajenderia, Alyaa Shamardel and Khaled Noureldin
Article Type: Systematic Review Article | First Published: May 20, 2020
Breast conservative surgery (BCS) and oncoplastic procedures are becoming more and more popular, providing better aesthetic outcome but one of the main draw-back of these procedures is involvement of the margin and return to theatre, causing undesired economic and cosmetic outcome in addition to psychological burden on the patients. Frozen section can decrease incidence of involved margin however, it is not always available in addition to increasing the cost. Using Intra-operative ultrasound (IO...