Open Access DOI:10.23937/2469-5726/1510085
Antiphospholipid Antibody-Related Problems, the Orphan Child of Medicine
Bruce Rothschild
Article Type: Commentary | First Published: August 29, 2020
Failure to routinely recognize and/or treat immunologic sources of thromboembolic disease has undermined our ability to improve the quality of life of the patients we serve and even compromised their survival. It’s time to bring it into the mainstream. Explanation for persistence of related oversights and potential resolution is presented. Failure to routinely recognize and/or treat immunologic sources of thromboembolic disease has undermined our ability to improve the quality of life of the p...
Open Access DOI:10.23937/2572-4010.1510039
The Effect Stool Transplantation as an Adjunct Treatment in Obesity in Rats
Cynthia Fontoura Klas, Rebeca Loureiro Rebouças, Giovanna Santos Piedade, Kader Osman, Luana Lima de Bastos, Gabriel Soares Martins de Souza, Felipe Menezes Varela de Araújo, Gabriela Franck Pasqual, Juliana Vogler de Arruda, Luiz Felipe Paludo Carmona, Camila Moraes Marques and Luiz Fernando Kubrusyl
Article Type: Original Article | First Published: August 22, 2020
Obesity is defined as a multifactorial metabolic syndrome, in which there’s an excessive number of fat cells within the tissues. It’s discussed that intestinal microbiota might have a relevant relation with obesity, since it’s relevantly altered in obese patients. To assess the effect of stool transplantation (ST) in the condition of obesity and its outcomes in an experimental model of cafeteria diet by hepatic function test, lipid profile, total glycemia and histology....
Open Access DOI:10.23937/2572-4193.1510088
Intratonsillar Abscess: Case Series of a Rare Entity
S Juthika Rai, Madhuri G and Chandre Gowda BV
Article Type: Case Series | First Published: August 29, 2020
Intratonsillar abscess (ITA) is a rarely reported clinical entity in both children and adults. Despite its rarity ITA should be considered in the differential diagnosis of Peritonsillar abscess and Tonsillitis. CT scan is useful to confirm the presence of an ITA. The following case series summarizes three cases of intratonsillar abscess that presented to our centre and their management. The primary treatment modality in our cases involved needle aspiration with post-procedural antibiotics....
Open Access DOI:10.23937/2572-4193.1510087
Zygomatic Arch Blastomycosis in a Pediatric Patient: A Case Report
Paige Kennedy, MD and Andrea Shogan, MD
Article Type: Case Report | First Published: August 14, 2020
Blastomycoses dermatitidis is a fungal organism endemic to the eastern United States. This organism is thought to grow in soil and decaying wood, and exposure with inhalation of the spores can result in blastomycosis, a potentially life-threatening disseminated infection. We present a case of an 11-year-old female who presented to our institution with headaches and left-sided facial swelling, who was ultimately found to have blastomycosisof her left zygomatic bone....
Open Access DOI:10.23937/2572-3243.1510084
Surgical Options for Treating Knee Osteoarthritis - A Concise Review
Jatinder Singh Luthra, FRCS, Salim AL Habsi, MD and Suwailim AL Ghannami, MRCS
Article Type: Review Article | First Published: August 21, 2020
Several options are available to manage osteoarthritis of the knee including arthroscopic joint debridement, high tibial osteotomy, proximal fibula osteotomy, Maquet osteotomy, joint distraction procedure, sub-chondroplasty, injection of platelet rich plasma, injection of stem cell, patellofemoral arthroplasty, unicompartment knee arthroplasty, and total knee replacement. The choice of surgery will depend on location and severity of the osteoarthritis, age, comorbidities, and body mass index of ...
Open Access DOI:10.23937/2474-3658/1510153
Statistical Analyses of COVID-19 Cases in India
Neha K Gadhvi
Article Type: Review Article | First Published: September 03, 2020
COVID-19 outbreak was first reported in Wuhan, China and has spread most of the countries of the world. The outbreak spreads are largely influenced by each country’s policy and social responsibility. According to WHO, the estimate of attack the rate on 23, June, 2020 to be between 1.4 to 2.5. In India the situation is somehow controllable compared to the situations of developed countries. It will be worth interesting to know about the fact and figures of corona cases in India. The different ty...
Open Access DOI:10.23937/2378-3648/1410051
Novel Variant in COL4A5 Gene Associated with X-linked Alport Syndrome
Eranga Sanjeewa Wijewickrama, Dineshani Hettiarachchi, Hwai Liang Loh, Lye Wai Choong and Vajira HW Dissanayake
Article Type: Case Report | First Published: August 22, 2020
Alport syndrome is an inherited disease of collagen IV leading to progressive glomerular sclerosis associated with variable degrees of proteinuria and haematuria, sensorineural deafness and ocular abnormalities. Here we describe a novel mutation involving the COL4A5 gene leading to X-linked Alport syndrome (XLAS) in a Singhalese family of six children born to nonconsanguineous parents of Sri Lankan origin. The eldest 19-year-old male was found to have microscopic haematuria and proteinuria. His ...
Open Access DOI:10.23937/2572-3286.1510057
Hyponatremia in COVID-19 Infection - Possible Causal Factors and Management
Jose Carlos De La Flor Merino, MD, Alexander Marschall, MD, Belen Biscotti Rodil, MD and Miguel Rodeles del Pozo, MD
Article Type: Commentary | First Published: August 28, 2020
SARS-CoV-2 disease (COVID-19) has dramatically increased since March 2020. There is insufficient data to establish the risk of acquiring the hyponatremia in patient with COVID-19 infection. The prevalence, clinical characteristics, severity, treatment and prognosis of hyponatremia in patients with pneumonia due to COVID-19 is not yet known, although several articles on kidney injury and electrolyte abnormalities have recently been described. IV fluid replacement should be administered with cauti...
Open Access DOI:10.23937/2572-3286.1510056
Efficacy and Safety of Thirst-Quenching Lozenges for Xerostomia in Patients Undergoing Hemodialysis: A Prospective, Single-Arm, Open-Label Study
Manisha Sahay, Alan Almeida, Syed Mujtaba Hussain Naqvi, Hariharan Venugopal, Ravindra Machhindra Kale, Pankaj Digambarrao Patil, Suyog Mehta and Amey Mane
Article Type: Clinical Trial | First Published: August 26, 2020
Xerostomia is a common symptom in patients with end-stage kidney disease (ESKD) undergoing hemodialysis and currently available treatments are of limited success. To evaluate the efficacy and safety of thirst-quenching lozenges (TQL) in patients with ESKD undergoing hemodialysis. Xerostomia is a subjective complaint of dryness of oral cavity and is frequently reported (28% to 67%) in patients with end-stage kidney disease (ESKD); including those on chronic hemodialysis. Xerostomia may be attribu...