Open Access DOI:10.23937/2474-3690/1510053
The Cardio-Vascular and Metabolic Treatments in Canada: Assessment of Real-Life Therapeutic Value Registry (CV-CARE): Registry Description and Baseline Patient Demographics
Goldenberg Ronald, Cheng Willoon, Bell Alan, Burrows Melonie Blavignac Jessica, Paron Emilia, Nadège Fils-Aimé and Barakat Maxime
Article Type: Research Article | First Published: December 12, 2020
Bausch Health Canada cardiovascular and metabolic treatment portfolio has been shown to be safe and effective in clinical trials. However, in clinical trials, data is collected in selective populations under ideal conditions, making inference to the real-world problematic. Well executed patient registries are required to provide evidence of the benefits of therapeutic agents under routine, real world conditions. The ‘Cardio-Vascular and metabolic treatments in Canada: Assessment of REal-life t...
Open Access DOI:10.23937/2378-3648/1410052
Y Chromosome Sequences in Turner Syndrome: Multiplex PCR, a New Method for Diagnosis
Lene Garcia Barbosa Maria Anunciação Souza, Adriana Aparecida Siviero-Miachon, Magnus Régius Dias-da-Silva and Angela Maria Spinola-Castro
Article Type: Brief Report | First Published: December 02, 2020
Turner’s syndrome is characterized by the partial or complete absence of one of the sex chromosomes in women in association with one or more clinical exposures. Molecular techniques such as polymerase chain reaction (PCR) are useful when it comes to complementing the genetic approach, as they present greater sensitivity in recognizing mosaicism. Considering the high percentage of mosaicism and the possible clinical impact of the presence of Y chromosome in these patients, we proposed in this s...
Open Access DOI:10.23937/2572-3286.1510060
The Effects of the Symptoms Experienced by Patients Undergoing Hemodialysis Treatment on their Comfort Levels
Rukiye Demir Dikmen and Hakime Aslan, PhD
Article Type: Original Article | First Published: December 17, 2020
This is cross-sectional study. The population of consisted of patients aged over 18 who received treatment at three hemodialysis centers in Elazig province and two in Bingol province. Sampling method was not used as it was aimed to reach the whole population. The research was carried out with 363 patients (84% of the population) meeting the research criteria. The data was collected between June-October 2019. Personal Information Form, Hemodialysis Comfort Scale (HDCS), and Dialysis Symptom Index...
Open Access DOI:10.23937/2469-567X/1510072
The Transformation of Burnet’s Immune Surveillance Cells into Natural Killer Cells and its Circumstances
Joseph Geza Sinkovics and Joseph Csaba Horvath
Article Type: Case Report | First Published: December 17, 2020
In 1969 it was very difficult to explain the sudden unexpected appearance of some finely granulated large lymphoid cells that had been hidden in the human blood for over a full century, as they suddenly revealed themselves in our laboratory at M.D. Anderson Hospital, Houston TX. At first, the hematopathologists considered these cells to be of monocytoid (M) derivation; by accidental misprint, instead of monocytoid noted as “macrophagic” in the legends. These new cells appeared clearly distin...
Open Access DOI:10.23937/2643-461X/1710041
Animal Trypanosomiasis in Cattle of Good Body Condition Score in the Adamawa Region of Cameroon: Hematological and Immunological Implications
Ebanga Echi Joan, Amadoh Jude Akumbu, Farikou Oumarou, Abba Samuel and Oumar Mahamat
Article Type: Research Article | First Published: December 23, 2020
The control of animal trypanosomiasis consists, amongst other things, the punctual treatment of new cases, primarily diagnosed by pastoralists on the basis of clinical signs. This practice suggests that many healthy infected animals are left untreated. In this study, animal trypanosomiasis in cattle of good body condition score was evaluated, the existence of polyclonal anti-trypanosome (Anti-tryps) and its serotherapy implications were discussed. From January to March 2020, the study was carrie...
Open Access DOI:10.23937/2469-5718/1510179
Match Running Performance and Positional Demands of a U9 Female Soccer Team Competing in a Parks and Recreation- Sponsored League
Brad H. DeWeese, Robert W. Sausaman, Matt L. Sams and Joanne Spalding
Article Type: Research Article | First Published: December 19, 2020
The purpose of this study was to describe the match play characteristics of female youth-athletes participating in recreation league U9 soccer via wearable Global Positioning System (GPS) technology. Nine female youth soccer athletes (8.6 ± 0.9 years; all with 3-4 years of playing experience) were monitored during the study period. The athletes participated in approximately 2.5 hours of soccer-related training per week and two 48-minute 9v9 matches per week. The athletes were classified as Forw...
Open Access DOI:10.23937/2469-5718/1510178
Intense Endurance Exercise: A Potential Risk Factor in the Development of Heart Disease
Jocelynn Rajanayagam, MD and Mohammed Alsabri, MD, M.B, B.S
Article Type: Review Article | First Published: December 17, 2020
Exercise is known to improve cardiac health; however, the upper limit of exercise is not as clear. High intensity endurance exercise and its association with cardiac dysfunction is becoming more important as more people in the USA participate in endurance activity. Increased cardiac remodelling, myocardial fibrosis, and arrhythmias were associated with increased endurance exercise in most instances. Clinically significant dysfunction from endurance exercise induced cardiac remodelling and myocar...
Open Access DOI:10.23937/2469-570X/1410070
Therapeutic Effect of Intravenously Administered Autologous Adipose-Derived Stem Cells on Chronic Stage Stroke Patients
Masamitsu Ichihashi, MD, PhD, Masaki Tanaka, MD, PhD, Takashi Iizuka, Narumi Nagoe, Youko Sato, Hitomi Takahashi, Asami Ueda, Hiroko Totsuka, Narumi Takanashi, Takahito Nishikata, PhD, Osamu Matsuo, MD, PhD, Hideya Ando, PhD and Ken-ichiMizutani, PhD
Article Type: Original Article | First Published: December 10, 2020
Intravenous transplantation of mesenchymal stem cells derived from bone marrow and adipose tissue has been reported to be effective, safe and promising in the recovery of clinical outcomes of the stroke patients at acute and subacute stages, but clinical studies at chronic stages are still limited. It is reported that for better recovery of neurological dysfunction, cell therapy is recommended as early as possible after stroke onset. To our knowledge, clinical studies on stem cell therapy of str...
Open Access DOI:10.23937/2378-3516/1410148
Platypnea-Orthodeoxia Syndrome Following Resection of an Intrathoracic Extrapulmonary Thymoma
Joseph Kojo Kittah and Anne Marie Matelski
Article Type: Case Report | First Published: December 14, 2020
We report the case of a 76-year-old female with no significant past medical history who developed Platypnea-orthodeoxia syndrome (POS) following thoracotomy with thymoma resection. Patient underwent right thoracotomy with resection of a 12 cm right lower lobe mass. The mass was “peeled gently from the pericardium and the aorta”, and compressed the right upper, middle, and lower lobes. No lung tissue was resected. Pathology indicated a type B1 thymoma. She was discharged on post-op day #4 wit...