Open Access DOI:10.23937/2469-5750/1510094

Treatment of Scar Contracture with Intralesional Jet-Assisted Injection of Hyaluronic acid

Daniel Cassuto and Yuri Vinshtok

Article Type: Case Series | First Published: December 30, 2020

Scar hypertrophy and keloid transformation very often present the cause of contracture. All current options for medical treatment of contracture have failed to give an immediate or near-time relief. In this case series we implemented a jet-injection method for intralesional delivery of hyaluronic acid and successfully achieved relief of surgical and burn scar contractures. The liquid jet permits an easy and tolerable penetration of hyaluronic acid into firm scar tissue. Biomolecular effect of HA...

 Open Access DOI:10.23937/2469-5734/1510122

Hemimaxillofacial Dysplasia/Segmental Odontomaxillary Dysplasia (HD/SOD): An Updated Review of 65 Cases and Report of an Unusual New Case

Kıvanç Kamburoğlu, Nurver Karslı, Ayşegül Köklü and Ömer Günhan

Article Type: Case Report | First Published: December 31, 2020

The aim of the present review was to analyze the literature and describe the clinical and radiographic features of HD-SOD. In addition, an unusual new case which was thought to be a subtle type of HD-SOD, involving a girl, was presented with detailed characteristics of HD-SOD. All HD-SOD cases published between 1987 and 2020, along with the present case, making a total of 66 cases, were evaluated according to criteria which included gender, age, and location of the lesion, clinical and radiologi...

 Open Access DOI:10.23937/2377-3634/1410133

Serum Vitamin D Levels in Persons with Type 2 Diabetes Mellitus in Lagos, Nigeria

Anyanwu AC, Olopade OB, Onung SI, Odeniyi IA, Coker HAB, Fasanmade OA and Ohwovoriole AE

Article Type: Original Article | First Published: December 30, 2020

The prevalence of Type 2 diabetes mellitus (T2DM) continues to climb in many parts of the globe in association with the rise in Obesity. In parallel to the increase in the prevalence of diabetes mellitus, evidence indicates a high prevalence of vitamin D deficiency Worldwide. Areas with high prevalence of vitamin D insufficiency and deficiency have been associated with a higher prevalence of diabetes. The reported prevalence of vitamin D deficiency among subjects with Type 2 diabetes mellitus ra...

 Open Access DOI:10.23937/2377-3634/1410132

Diabetic Foot Profile in Patients under Regular Haemodialysis

Nasreddine Boughallaba and Habib Ksouri

Article Type: Original Article | First Published: December 23, 2020

Diabetic foot syndrome that affects patients under regular haemodialysis is a complex mechanism mainly based on patient metabolism, neurosensitive abnormalities, and plantar pressure dysfunctions. Our work is based on a descriptive cross-sectional and multicenter study conducted during 45 days and concerning 43 diabetic patients among a total of 193 patients undergoing regular haemodialysis in three haemodialysis centers in Tunisia. Data collection relied on patients clinical records, all data w...

 Open Access DOI:10.23937/2377-3634/1410131

Xenotransplantation of the Pancreas: A Reality Check of Its Historical Emergence

Cyprian Weaver

Article Type: Historical Analysis | First Published: December 21, 2020

Recent advancements being made in the humanization of Crispr-based gene-edited animals have now provided a sophisticated molecular platform for exogenic organ production and xenotransplantation. Although this amazing and novel medical step into the future holds significant therapeutic promise for pancreas xenotransplantation presently impeded by lack of sufficient donors, its origins arose in an era that is often portrayed as an age of medical quackery and iatrogenesis. The present study reexami...

 Open Access DOI:10.23937/2378-2951/1410210

Changes and Outcome of Cardiac Function in Children with SARS-CoV-2 Multisystem Inflammatory Syndrome

Chloé Huet, MD, Thibault Blache, MD, Thomas Perouse de Montclos, MD, Claire Bertail Galoin, MD, Cécile Leconte, MD, Mohamed Bakloul, MD, Etienne Javouhey, MD, PhD, Elodie Perdreau, MD and Sylvie Di Filippo, MD, PhD

Article Type: Original Article | First Published: December 26, 2020

Cardiac involvement has been reported in children with SARS-CoV-2 inflammatory syndrome. The objectives herein were to assess changes in cardiac parameters and compare cardiac pathologies observed in SARS-CoV-2 to Kawasaki-(KW) and myocarditis-(MY). Patients < 18 years of age, with symptoms of Kawasaki disease (KW group) and/or of acute myocarditis (MY group) from March 1 to May 31 2020 were included. Clinical, laboratory data, and cardiac parameters were recorded upon diagnosis and at several p...

 Open Access DOI:10.23937/2690-3172/1710010

Chiasmus as an Alternative Pattern of Teaching

Dhouha Bacha, Wael Ferjaoui, Lasaad Gharbi, Sana Ben Slama and Ahlem Lahmar

Article Type: Editorial | First Published: October 15, 2020

Etymologically the word chiasm comes from the Greek word khiasmós which means crossing. The chiasm construction is a repetition crossing 2 segments A-B around a center C creating an AB/C/BA structure. This is a rhetorical figure of speech expressing repetition. In linguistics, the purpose of repetition is the emphasis on the message to be conveyed. In pedagogy, the 3 goals of repetition are: Consolidation, deepening and feedback. In the domain of procedural knowledge, repetition makes it possib...

 Open Access DOI:10.23937/2377-4630/1410116

Meta-Analysis and Evidence Base for the Efficacy of High Frequency Oscillatory Ventilation (HFOV) in ARDS Management: Systematic Review and Quality Assessment

Mohamed E Awad, MD, MBA, Mohamed Gaber, MD, Suhib I Alhusban, MD, Sung Chu, BS, Colville HB Ferdinand, MD, FACS and Mohamed Ben Omran, MD

Article Type: Original Article | First Published: December 30, 2020

To evaluate the efficacy of high frequency oscillatory ventilation (HFOV) in management of acute respiratory distress syndrome and determine whether if there is any superiority over the conventional mechanical ventilation (CMV). A systematic review and meta-analysis were conducted according to PRISMA checklist and the Cochrane Handbook for Systematic Reviews of Interventions. The search of the literature was performed through several search databases: PubMed, MEDLINE via Ovid, and web of science...

 Open Access DOI:10.23937/2469-5823/1510150

Nursing Students' Anxiety Levels and Coping Strategies during the COVID-19 Pandemic

Zeynep Temiz, PhD

Article Type: Research Article | First Published: December 30, 2020

Anxiety is very prevalent among nursing students even in normal circumstances. In Turkey during the COVID-19 pandemic, nursing students encountered a new reality of that includes economic uncertainty, fear of infection, the challenges of distance education and more. This study was carried out to determine the relationship between the anxiety levels and the coping methods of nursing students during the COVID-19 pandemic. This study was carried out to determine the relationship between the anxiety...

 Open Access DOI:10.23937/2378-3656/1410332

Medication-Related Osteonecrosis of the Jaw by Concomitant Nivolumab and Denosumab Treatment

Gianfilippo Nifosì, Lorenzo Nifosì and Antonio Fabrizio Nifosì

Article Type: Case Report | First Published: December 31, 2020

Medication-related osteonecrosis of the jaw is a multifactorial disease described in association with antiresorptive drugs, such as bisphosphonates and denosumab. More recently, cases due to non-antiresorptive medications, particularly, some cases by immune checkpoint inhibitors, have also been reported. Dentists and oral surgeons in the coming years will see an increasing number of patients who are receiving treatment potentially toxic to bone. We reported a case of a cancer patient treated wit...