Open Access DOI:10.23937/2377-4630/1410130
Anesthetic Management in a Parturient with Thrombotic Thrombocytopenic Purpura for Cesarean Section: A Case Report and Literature Review
Dimitra Karantoula, Emmanouil Stamatakis, Sofia Hadzilia, Panagiotis Antsaklis and Dimitrios Valsamidis
Article Type: Case Report and Review Article | First Published: December 20, 2021
Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy (TMA) characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and organ ischemia linked to disseminated microvascular platelet rich-thrombi. TTP is specifically related to a severe deficiency of ADAMTS13, a cleaving protease for von Willebrand (vWF). TTP is occurring in between 1 and 13 cases per million people depending on geographic location, and 1 in 25,000 pregnancies. We ...
Open Access DOI:10.23937/2643-4466/1710035
Clinical Predictors of In-Hospital Outcomes in COVID-19 Patients: A Retrospective Cohort Study
Maiara A Floriani, MSc, Marina Bessel, ScD, Isabelle W Zorzo, BSHCA, Andressa B Glaeser, BSc, Rafael Domingos Grando, MD, Raphael Goveia Rodeghiero, MD, Mohamed Mutlaq Parrini, BEcon, MPhil, Gisele Nader Bastos, MD, ScD and Luiz Antonio Nasi, MD, ScD
Article Type: Research Article | First Published: December 31, 2021
We do not have detailed evidence on conditions or treatments that act as predictors of hospital outcomes. To identify the clinical predictors of hospital outcomes in COVID-19 patients and to evaluate the effect of therapeutic’s interventions on length of stay, ICU admission, need for mechanical ventilation (MV) and mortality. The primary outcome was to assess whether any treatment alone or in combination with standard care, was able to reduce ICU admission, need for MV or mortality. The second...
Open Access DOI:10.23937/2572-407X.1510028
A Rare Case of Bullosis Diabeticorum Restricted to the Trunk
I. Hallab, H.Titou, R. Frikh, N. Hjira and M. Boui
Article Type: Case Report | First Published: December 31, 2021
Diabetes bullosis is a chronic manifestation, a specific cutaneous marker, of diabetes mellitus essentially insulindependent. It is very rare. Its etiology is still unknown. It is seen more frequently in long-standing diabetic patients commonly with peripheral neuropathy, retinopathy, or nephropathy. The lesions are usually asymptomatic. There are no specific tests for DB. The diagnosis is based on characteristic findings, clinical course, and the exclusion of other bullous disorders. Its evolut...
Open Access DOI:10.23937/2378-3656/1410378
One Head Trauma, Three ENT Manifestations
Pedro Santos, MD, Ângela Rego, MD, Isabel Carvalho, MD and Luís Meireles, MD
Article Type: Case Report | First Published: December 31, 2021
It is well known that head trauma (HT) can cause hypoacusis; as well as benign positional paroxysmal vertigo (BPPV) and anosmia, which are frequently referred as sequelae of HY. However, the post-HT triad of BPPV, hypoacusis and anosmia is extremely rare to occur in the same patient, with only two cases reported in the literature. With this case report we wish to describe a clinical case of HT that caused hypoacusis, BPPV and anosmia as sequelae, and to review the importance of ENT evaluation in...
Open Access DOI:10.23937/2378-3656/1410377
Acute Limb Ischemia as an Unusual Presentation of Spontaneous Coronary Artery Dissection
Basel Musmar and Alaa Gabi
Article Type: Case Report | First Published: December 31, 2021
Spontaneous coronary artery dissection (SCAD) is a rare, though, important cause of acute coronary syndrome that is more commonly seen in young and middle-aged women without risk factors for, or a history of, coronary artery disease. Acute embolization of left ventricular (LV) thrombus is an uncommon but known cause of acute limb ischemia. In this case, we present a rare case of SCAD that led to acute limb ischemia due to embolization of LV thrombus. A 53-year-old female with a past medical his...
Open Access DOI:10.23937/2572-4061.1510042
Biochemical Changes in Hematological and Liver Parameters in Albino Rats Exposed to Azo Dye Adulterated Palm Oil
Kola-Ajibade Ibukun R, Jegede Rotimi J and Olusola Augustine O
Article Type: Original Article | First Published: December 26, 2021
In West Africa, the manufacturing and processing of palm oil are done on a small, medium, and large scale, it is therefore almost impossible to detect fraud in the system. A major disadvantage associated with the use of adulterants in palm oil is that the adulterants have not undergone adequate research and the degree of health hazards they can pose to humans when consumed. This study was designed to evaluate the toxic effects of azo dye adulterated palm oil on hematological and liver parameters...
Open Access DOI:10.23937/2572-4061.1510041
Effects of Azo Dye Adulterated Palm Oil on the Expression of Inflammatory, Functional, Antioxidant Markers and Body Weights in Albino Rats
Kola-Ajibade Ibukun R, Atere Grace and Olusola Augustine O
Article Type: Original Article | First Published: December 25, 2021
Food is important to life and the continuous exposure to food throughout an individual’s lifetime renders diet the most important environmental factor challenging the biological system. Only few studies exist for evaluations of the toxicological effects of adulterated palm oil on biochemical parameters. This study was undertaken to evaluate the expression of the activity of inflammatory enzymes (TNF-α, MCP-1), antioxidant enzymes (GPx-1, CAT) and functional markers (EPO, ALB, CRIM) in liver, ...
Open Access DOI:10.23937/2572-4053.1510038
Sleep Apnea Syndrome and Covid-19 Infection Correlation: Treated/Not Treated OSAS Patients Comparison
Francesca Francese, Giuliana Conte and Mario Ermani
Article Type: Research Article | First Published: December 17, 2021
This work is intended to study respiratory function during sleep in positive Covid patients in order to evaluate the presence of sleep apnea syndrome as risk factor that predispose to Covid infection. Data shows that the comorbidities in Covid patients are obesity, hypertension, diabetes and cardiovascular diseases. The reason consists in snoring; the vibrations of the soft walls cause an inflammation of the upper airways, over time increasing inflammation, respiratory events increase. We have s...
Open Access DOI:10.23937/2474-3658/1510241
Post-Artesunate Delayed Hemolysis after Treatment of Malaria with Intravenous Artesunate: A Case Study
Abigail Foster
Article Type: Case Report | First Published: December 24, 2021
Delayed hemolysis is an uncommon reaction to intravenous artesunate for the treatment of severe malaria. We report a case of a patient who developed severe malaria after initial inadequate treatment, thus requiring IV artesunate therapy. Delayed hemolytic anemia then occurred and was monitored for weeks after completion of treatment. Malaria is a vector-borne infectious parasite that is transmitted through mosquitoes. It is a very prevalent disease globally, usually in areas of the world that ar...
Open Access DOI:10.23937/2474-3658/1510240
Effects of Race on the Outcome of COVID-19 in Hospitalized Patients
Getahun Abate, Aniruddh Kapoor, Edward Charbek, Bryan Beck, Qian Wang, Grace C Wang, Mackenzie Steck, Jason Zoglman, Robin R Chamberland, Sharon Frey, Daniel F Hoft and Timothy L Wiemken
Article Type: Research Article | First Published: December 24, 2021
Recent reports indicate that African Americans have higher mortality rates from SARSCoV- 2 coronavirus disease 19 (COVID-19) compared to Caucasians, with more marked differences in the Midwest region of the US. This study was performed to study differences in COVID-19 related mortality and hospital length of stay (LOS) between African Americans and Caucasians in Midwest setting, and identify factors associated with mortality and LOS. Data were collected from the electronic health records (EHR) ...