Diagnostic Findings in 60 Cases of Isolated and Syndromic Congenital Olfactory Dysfunction
Jean-Jacques Braun, MD, Marion Renaud, MD, Sebastien Moliere, MD, Vincent Noblet, MD, Stephane Kremer, MD, Helene Dollfus, MD and Sophie Riehm, MD
Article Type: Original Article | First Published: April 15, 2019
Congenital anosmia (CA) is rare comparatively to acquired anosmia. The pathophysiology and the genetic background remain poorly understood. This study aims to review the main clinical and Magnetic Resonance Imaging (MRI) findings to discuss the diagnostic strategy, the pathophysiology and the genetic basis of the different forms of CA. A series of 60 patients with congenital anosmia was reviewed retrospectively out of 425 non-sinus-related anosmia and compared to the literature data. CA was asse...
Investigation of Serum Levels of Leptin, Ghrelin and Growth Hormone in Bahraini Children with Autism
Zuheir Ahmed Hasan, PhD, Ghada Al-Kafaji, PhD, Maryam Isa Al-Sherawi, PhD, Rima Abdul Razzak, PhD, Diab Eltayeb, PhD, Cristina Skrypnk, MD, PhD and Moiz Bakhiet, MD, PhD
Article Type: Original Article | First Published: March 11, 2019
Autism is a complex neurodevelopmental disorder, the pathogenesis of which remains unclear. Recent research suggests a possible role of hormonal abnormalities in the pathogenicity of autism. In this investigation, we measured serum levels of leptin, ghrelin, and growth hormone (GH) in 40 age-matched Bahraini children, 20 with autism (16 males and 4 females) and 20 healthy children (13 males and 7 females). Hormonal levels were measured by enzyme-linked immunosorbent assay method....