Citation

Mariniello G, Peca C, De Caro MLDB, Corvino S, Orlando V, et al. (2019) Cerebello-Pontine Angle Glioblastoma with Cervical Spine Metastasis: A Case Report. Neurosurg Cases Rev 2:012. doi.org/10.23937/ncr-2017/1710012

Copyright

© 2019 Mariniello G, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

CASE REPORT | OPEN ACCESS DOI: 10.23937/ncr-2017/1710012

Cerebello-Pontine Angle Glioblastoma with Cervical Spine Metastasis: A Case Report

Giuseppe Mariniello, MD1, Carmela Peca, MD1, Maria Laura Del Basso De Caro, MD2, Sergio Corvino, MD1, Valentina Orlando, MD1, Elia Guadagno, MD2 and Francesco Maiuri, MD1*

1Department of Neurosciences and Reproductive and Odontostomatological Sciences, Neurosurgical Clinic, University of Naples Federico II, Naples, Italy

2Department of Advanced Biomorphological Sciences, University of Naples Federico II, Naples, Italy

Abstract

This article reports a left cerebellopontine angle glioblastoma presenting with two week history of rapidly progressive hearing loss and trigeminal pain, treated by subtotal resection and radiotherapy with concomitant and adjuvant temozolomide. At one year, local tumor control and diffuse neoplastic seeding in the cervical spinal cord were evidenced.

Glioblastomas involving the cerebellopontine angle are exceptional with only 10 reported cases. The possibility of a glioblastoma should be considered in the differential diagnosis of malignant cerebellopontineangle tumors. The standard treatment including maximum tumor resection and Stupp protocol is justified to obtain local tumor control.