A 55-years-old female presented with pain in the right eye for 15 days. She had a history of complicated cataract surgery followed by pars plana vitrectomy, intraocular gas injection and sulcus fixated intraocular lens implantation. On ophthalmologic examination, pupillary capture by intraocular lens, shallow anterior chamber, corneal edema and elevated intraocular pressure despite maximum medical therapy was observed. Intraocular gas induced secondary pupillary block glaucoma diagnosis was made. She underwent intraocular lens reposition and peripheral iridectomy surgery in the same session. Intraocular pressure reduced dramatically after the procedure in addition to anterior chamber deepening. In this case report, we highlighted the very rare cause of pupillary block glaucoma and its management.