Journal of

Sleep Disorders and ManagementISSN: 2572-4053


 Open Access DOI:10.23937/2572-4053.1510027

Vitamin B12 and Circadian Rhythm Sleep Disorders: Patient Treatments vs. Controlled Studies

Behrooz Kamgar-Parsi, PhD

Article Type: Commentary | First Published: December 30, 2019

Despite earlier reports of success, controlled studies have not confirmed the effectiveness of vitamin B12 in treating circadian rhythm sleep disorders. We try to explain why these two types of studies do not produce similar results. Individuals with circadian rhythm sleep disorder suffer from recurrent patterns of disrupted sleep that can significantly affect their daily functioning. Evidence suggests that vitamin B12 supplements may have a beneficial effect on sleep patterns. However, researc...

 Open Access DOI:10.23937/2572-4053.1510026

Cluster Analysis and Phenotyping Based on Association of Sleep Studies and Cardiovascular Comorbidities

John Arek Kileci, Derya Arkonac, Leslie Seijo and Alfredo Astua

Article Type: Research Article | First Published: August 28, 2019

Obstructive Sleep Apnea (OSA) is a complex disease process with a known significant association with cardiovascular diseases and the metabolic syndrome. This study aimed to define phenotypes of OSA based on sleep studies and cardiovascular comorbidities and to further investigate whether there would be any meaningful association between these disease processes. Defining phenotypes could assist in individual targeted treatments for patients with OSA....

 Open Access DOI:10.23937/2572-4053.1510025

Chronotherapy for the Treatment of Hypertension among Patients with Obstructive Sleep Apnea: A Systematic Review

Magdalena Deaton, MPH, MSN, RN, AGNP-C, Jeanne Ruff, MPH, BSN, RN and Lisa Boss, PhD, RN, CNS, CEN, CNE

Article Type: Research Article | First Published: July 26, 2019

Hypertension (HTN) and obstructive sleep apnea (OSA) are associated with increased risk for adverse cardiovascular events. Comorbid HTN with OSA is often resistant to pharmacologic treatment. Chronotherapy, the timing of treatment based on circadian rhythms, may prove to be a valuable, cost-effective tool for improving blood pressure (BP) control among those with OSA. This Systematic Review appraises the existing literature regarding morning (a.m.) vs. evening (p.m.) administration of antihypert...

 Open Access DOI:10.23937/2572-4053.1510024

Epileptiform Activity in Patient with RBD-Like Symptomatology

Isabel Loucao Amorim, MD, Linda Azevedo Kauppila, MD, Mariana Reis Costa, MD, Carla Bentes, MD, PhD, and Rita Peralta, MD

Article Type: Case Report | First Published: July 06, 2019

REM sleep behavior disorder shares some clinical similarities with nocturnal epileptic seizures, which can result in misdiagnosis. We report a case of a man with Parkinson Disease diagnosis and parietal and frontal meningiomas who started to have abnormal sleep behaviors, suggestive of REM sleep behavior disorder. Video-polysomnographic showed periodic bilateral occipital epileptiform activity that occurred near arousals, where subtle movements were detected. During REM sleep no loss of atonia n...

 Open Access DOI:10.23937/2572-4053.1510023

Observations on Restless Legs Syndrome and Indications of the Cause

Melrose Truett Garrett, Jr. Sc.D

Article Type: Short Note | First Published: June 24, 2019

RLS accompanying loose stool (not diarrhea) indicated two hypotheses: 1) Medications for diarrhea will relieve RLS, 2) RLS is caused by pressure in the colon blocking a femoral vein, the nervous system then causes muscle contraction in the leg. In tests both were sustained. Soluble fiber corrects loose bowels but the number of Americans with insufficient fiber is much greater than those with RLS....

 Open Access DOI:10.23937/2572-4053.1510022

Novel Anti-Snoring Mouthpiece to Reduce Snoring in At-Home Study

Jonathan Greenburg, DDS, Jesse Cozean, MBA and Colette Cozean, PhD

Article Type: Clinical Trial | First Published: June 10, 2019

Habitual snoring affects millions of individuals and their partners, but often goes unresolved due to the high cost of care and other barriers to treatment. The purpose of this study was to evaluate the effectiveness of a novel intraoral device that restrains the tongue in an overthe- counter setting in a population of habitual snorers. Individuals who self-reported snoring enrolled in the study and were sent an investigational device. After signing the informed consent, they completed an initia...

 Open Access DOI:10.23937/2572-4053.1510021

Tactile Hallucinations in Rheumatoid Arthritis Patient in Use of Agomelatine, Painkiller and Methotrexate, Case Report and Possible Mechanisms

Natalia Pinho de Oliveira Ribeiro, Alexandre Rafael de Mello Schier, Christina Maria Pinho de Oliveira and Adriana Cardoso Silva

Article Type: Case Report | First Published: May 27, 2019

Rheumatoid arthritis (RA) is an autoimmune disease. RA patients may undertake traditional therapy with antidepressants to control the depressive symptoms and to reduce their pain levels. This is the case of a patient with RA who presented with tactile hallucinations. On the second day of the pain crisis, the RA patient used agomelatine and a painkiller and showed symptoms of tactile hallucination. This is the first report of tactile hallucinations in this context....

 Open Access DOI:10.23937/2572-4053.1510020

Is Post-Operative High Dependency Admission Required for Children with Obstructive Sleep Apnea after Adenotonsillectomy?

Chu Qin PHUA, Yi Rong Leonora LIU, Pei Yuan FONG, Kay Yee Winnie FUNG and Kun Kiaang Henry TAN

Article Type: Retrospective study | First Published: April 29, 2019

The commonest cause of paediatric obstructive sleep apnoea (OSA) is the disproportionate adenotonsillar hypertrophy in relation to craniofacial growth and airway calibre. In recent years, there is an increasing awareness of paediatric OSA, leading to increasing number of adenotonsillectomy being performed for this indication. Adenotonsillectomy has been shown to confer improvement in child behaviour and quality of life. In up to 79% of patients, it can lead to normalisation of polysomnography......

Volume 5
Issue 1