Open Access DOI:10.23937/2572-3235.1510102

Pulmonary Embolism and COVID-19: A Diagnostic Dilemma – A German Single Centre Experience

M Alami, D Janati-Idrissi, T Lohmann, B Osswald, G Plehn and K Luedtke

Article Type: Research Article | First Published: January 07, 2023

The high predisposition to pulmonary embolism (PE) in CoViD-19-patients increases with its seriousness, even under anticoagulation. Because neither clinical nor laboratory parameters seem to be specific in this case, the CTPA stays the gold standard for further diagnostic, with the risk however of overuse. Our study investigates the incidence of PE in CoViD-19-patients, who underwent aCTPA, and to assess the link of several clinical and laboratory parameters with its occurrence....

 Open Access DOI:10.23937/2572-4061.1510051

Acute and Sub-Acute Toxicity Studies on the Trunk Bark Hydro- Ethanolic Extract of Stereospermum kunthianum Cham: In Wistar Rats

Dieynaba KONE, Abdou SARR, Fatoumata BAH, Serigne Ibra Mbacké DIENG, Aminata TOURÉ, Alioune Dior FALL, Mathilde CABRAL and Mamadou FALL

Article Type: Research Article | First Published: January 29, 2023

The aim of the present study was to evaluate the acute and sub-acute toxicity of the trunk bark hydro- ethanolic extract of Stereospermum Kunthianum Cham: in Wistar rats. For acute toxicity assessment, three 12-week-old female rats were administered by gavage a single oral dose of 2000 mg/kg of the trunk bark hydro-ethanolic extract of Stereospermum kunthianum. LD50 was estimated after 14 days of observation. Subacute toxicity was assessed at three dose levels: 500, 1000, and 2000 mg/kg....

 Open Access DOI:10.23937/2572-4193.1510131

Long COVID and COVID-Induced Ménière’s Disease: Overview and Recommendations

Elizabeth S England-Kennedy, PhD, MPH, CHES and Mahmoud Abdelfatah, BPS, MBA, FPGEE

Article Type: Literature Review | First Published: January 29, 2023

SARS-CoV-2, the infectious agent causing the ongoing COVID-19 pandemic, often has long-term impacts on the health of those who survive initial infection and can lead to premature death. An understudied outcome of COVID-19 is its effect on the audiovestibular system. Impacts of the virus on this system create a pattern of disability similar to that of Ménière’s Disease (MD), a progressively degenerative condition that can cause severe falls and deafness. COVID-induced MD (CMD) impacts physica...

 Open Access DOI:10.23937/2469-5858/1510142

Bullous Pemphigoid in Older Adults Treated with DPP4i: A Case Series

Ávila-Fernández Katia Fabiola, Álvarez-Cisneros Teresa and Ruelas-Villavicencio Ana Lilia

Article Type: Case Series | First Published: January 29, 2023

Bullous pemphigoid (BP) is a rare autoimmune subepithelial blistering disease affecting mostly older adults . Studies have calculated an annual incidence ranging from 2.4% to 21.7% per million population. While triggers are found in less than 15% of cases, drugs are well-known trigger factors. Recently, dipeptidyl peptidase-4 inhibitors (DPP4i) have been associated to this condition. Our study presents four cases of older adults with BP associated to the use of DPP4i. The relevance of this study...

 Open Access DOI:10.23937/2469-5750/1510120

Acne Scars: Prevalence and Impact on Quality of Life in Moroccan Patients

Hasna Kerrouch, Youssef Zemmez, Rachid Frikh and Naoufal Hjira

Article Type: Research Article | First Published: February 01, 2023

Acne is a common dermatologic condition affecting more than 80% of 11 to 30-year-olds, who often suffer from acne scars. Despite the scarcity of data, acne scarring is thought to negatively impact the quality of life of patients. Therefore, the aim of the present study was to evaluate the prevalence of acne scars and their impact on the quality of life (QOL) in moroccan acne patients....

 Open Access DOI:10.23937/2378-3516/1410184

Effectiveness of Prone Positioning versus Supine Positioning in Patients Suffering from Refractory ARDS: A Meta-Analysis

James A Wright

Article Type: Research Article | First Published: January 25, 2023

Prone positioning (PP) was advocated more than 40 years ago as a means of improving the oxygenation status in patients exhibiting acute respiratory failure (ARF) and acute respiratory distress syndrome (ARDS). The purpose of this meta-analysis is to determine if prone positioning (PP) is a more effective way of treating ARDS patients than supine positioning (SP) in patients that are refractory to conventional mechanical ventilation....

 Open Access DOI:10.23937/2572-4037.1510059

Suicide Preventon and Management in Children and Adolescents: In Contemplaton of a Philosophical Approach

Rabi Ilemona Ekore

Article Type: Review Article | First Published: January 25, 2023

The periods of childhood and adolescence are those during which children and adolescents experience rapid transitions that may be difcult to cope with. The changes can be stressful for some older children or adolescents who may subsequently seek ways to cope, some of which may be maladaptive. The ensuing cascade of events triggers latent mental health issues in those already predisposed. Commensurate increase in eforts to provide help to vulnerable groups focuses on the psychological, social, an...

 Open Access DOI:10.23937/2643-3885/1710080

Charcot-Marie-Tooth Disease: Updates in Diagnosis and Treatment Guidelines Pertaining to the Lower Extremity and Case Study

Jonathan Furmanek, DPM, HTL, Amar Gulati, DPM, Anissa Hashemi Awwal, DPM, Fahd M Moeez, DPM, MBBS, Prakash Panchani, DPM, Caitlin Zarick, DPM, Eugene Batelli, DPM and Paul Carroll, DPM

Article Type: Literature Review, Surgical Tips, and Case Presentation | First Published: January 29, 2023

Diagnosis and treatment of Charcot-Marie-Tooth (CMT) can present as a challenging issue. Several published studies have demonstrated the complexity of diagnosis and treatment with an increasing role of genetics in diagnosis. The goal of this review is to contribute an updated and concise overview to the limited body of literature. This review elaborates on the published data with regard to discussing the presence of CMT disease and manifestation of various foot and lower extremity deformities in...

 Open Access DOI:10.23937/2469-5696/1410089

The Relationship between Serum Ferritin and Platelet Count in Yemeni Blood Donors

Boshra Al-Absi and Mohammed Abdul Wahid Almorish

Article Type: Original Article | First Published: January 26, 2023

Regular blood donation often cause iron deficiency. Changes of platelet count have been associated with iron deficiency anemia. We aimed to study the correlation between serum ferritin and platelet count in blood donors. Full blood count was measured by Sysmex- KX- 21N Haematology Analyser. Serum ferritin was examined using electrochemiluminescence technology of Cobas e 411 Analyzer....

 Open Access DOI:10.23937/2643-3966/1710054

Cardiovascular Disease as a Chronic Sequel to COVID-19: A Case Report

Oscar Rene Vazquez Melo, Ramon Eduardo Garcia Cahuich, Jose Julián Sosa Rodriguez and María Valeria Jiménez Báez

Article Type: Case Report | First Published: January 26, 2023

COVID-19 infection has shown cardiovascular involvement, particularly when it has a moderate to severe presentation. This alteration has been manifested in arrhythmias, myocarditis, and acute myocardial infarction, among others; persistence of these cardiovascular alterations in the short and medium term has been documented. In Latin America there are no reports of long-term cardiovascular sequelae. We present the case of a 46-year-old female with no previous history of cardiovascular disease wh...