Open Access DOI:10.23937/2572-3286.1510086

Efficacy and Safety of Sofosbuvir-Based Regimens in Patients with Viral Hepatitis C and Stage 4 and 5 Chronic Kidney Disease: The Cameroon Experience

Martial Tsiazok Dongmo, Mathurin Pierre Kowo, Aristide Eric Nono Tomta, Hermine Danielle Fouda Menye, Maïmouna Mahamat, Dorothe Soh Mankong, Linda Njonkam Toukep, Larissa Mbomena Tabene and François JérômeKaze Folefack

Article Type: Research Article | First Published: 2023/05/25

Treatment of viral hepatitis C in chronic kidney disease patients with glomerular filtration rate < 30 ml/min/1.73 m2 remains a challenge in countries with combinations containing only sofosbuvir. We investigated the efficacy and safety of sofosbuvir based regimens in patients infected with hepatitis C virus and stage 4 and 5 chronic kidney disease....

 Open Access DOI:10.23937/2469-584X/1510092

Dengue Fever in Liver Transplant Recipients: A Report of 3 Cases

Sachin Jain and NR Dash

Article Type: Case Series | First Published: 2023/06/15

Presented 3 months after transplantation with history of febrile illness with myalgia, arthralgia, thrombocytopenia, leukopenia. His low platelet and WBC counts were initially attributed to hypersplenism. Dengue was diagnosed using NS1antigen test and he was managed conservatively as for dengue fever. He recovered well and his graft is functioning well till last follow up....

 Open Access DOI:10.23937/2469-567X/1510087

Aids and Non-Hodgkin Lymphoma: Report of a Case

López de la Cruz Denisse, Azucena Casanova Lara and María Valeria Jiménez Báez

Article Type: Case Report | First Published: 2023/06/15

AIDS (Acquired Immunodeficiency Syndrome) is a condition caused by the Human Immunodeficiency Virus (HIV). HIV is a virus that attacks the immune system and weakens the body's ability to fight off infections and diseases. Approximately 37.6 million people (about twice the population of New York) worldwide are infected with the human immunodeficiency virus (HIV) according to data from the Joint United Nations Program on HIV-AIDS....

 Open Access DOI:10.23937/2572-4045.1510070

Monitoring of Viral Opportunistic Infections in Pediatric and Adult Cuban Transplant Recipients

Vivian Kourí, Consuelo Correa, Yenisleidys Martínez, Lizet Sánchez, Yoana Baños, Lissette Pérez, Grehete González, Yudira Soto, Bertha González, José Carnot, Niurka Verdecia, Anselmo Abdo-Cuza5, Marcia Samada5, Fernando González, Alejandro Roque, Daimiris Méndez, César E. Silverio, Jose Florin, Norma Hondal and Juan C. Jaime

Article Type: Original Article | First Published: 2023/05/22

Viral DNA was detected in 45.3% of the patients. Most patients tested positive for CMV (25.4%) or BK (21.2%). Although some differences in the frequency and type of viruses were observed between bone marrow and solid organ transplant, no association between viral load, virus disease and transplant type in adult or pediatric recipients was found. Analyzing all the recipients together, CMV was more frequently detected in serum and in patients with symptoms and complications. ...

 Open Access DOI:10.23937/2469-5718/1510252

Effect of Physiotherapy Applications on Inflammatory Markers in Asthma Disease

Özden Gökçek and Ufuk Yurdalan

Article Type: Review Article | First Published: 2023/05/26

Chronic systemic diseases associated with asthma cause an increase in the burden of health services, a reducation in the quality of life of individuals, and a decrease in work efficiency. Obesity, which plays a role in the reduction of pharmacological effects in the treatment of asthma, increases with sedentary life. A significant reduction in obesity is observed with exercise applications. Obesity is an important risk factor for asthma and also increases the severity of the disease by causing a...

 Open Access DOI:10.23937/2469-5718/1510251

Treadmill Exercise Testing on Different Blood Genotypes among University Students

Angela Member Danborno and Terhide Iorhemen Kyeleve

Article Type: Original Article | First Published: 2023/05/13

The benefits of regular exercise are overwhelming, be it in children, teens or adult. The phrase "exercise is medicine" has continously been used to emphasize the physiological, pshychological and social benefits of exercise. This research aims at comparing the effect of blood genotype and exercise on some physiological parameters in fit and willing undergraduate students....

 Open Access DOI:10.23937/2469-570X/1410079

Role of CD9 Sensing, AI, and Exosomes in Cellular Communication of Cancer

Neda Baghban, Sai Priyanka Kodam and Mujib Ullah

Article Type: Original Article | First Published: 2023/05/20

Exosomes are small membrane-bound vesicles that are released by various types of cells, including cancer cells, and play a role in intercellular communication. CD9 is a protein that is involved in cell signaling and adhesion. It is found on the surface of various cells, including cancer cells, and has been implicated in the communication between cancer cells and their microenvironment. Exosomes are small membrane-bound vesicles that are released by cells and contain various bioactive molecules, ...

 Open Access DOI:10.23937/2572-3235.1510108

Renal Pedicle Injury: A Case Report

Wafaa Bzeih, MD, Sajida Fawaz Hammoudi, MD, Jana Sleiman, MD and Oussama Rihan, MD

Article Type: Case Report | First Published: 2023/05/28

Around 10% of abdominal trauma injuries are accounted for renal injuries [1]. And amongst renal injuries, renal pedicle injuries are extremely rare. Renal pedicle injury is defined by the American Association for the Surgery of Trauma (AAST) as grade V renal injury in which the kidney is either shattered, has avulsion of renal hilum or laceration of the main renal artery or veincausing devascularization, or is devascularized with active bleeding....

 Open Access DOI:10.23937/2572-3235.1510107

Multiple Sclerosis Brain: Beyond Hyperintense Images

Bárbara Aymeé Hernández Hernández, MD, PhD

Article Type: Original Research Article | First Published: 2023/05/25

Multiple Sclerosis (MS) is defined as a chronic, inflammatory demyelinating disease of the central nervous system. It has a multifactorial origin and it is characterized by disabling inflammatory attacks in the central nervous system. It affects any functional system (visual, motor, sensory, coordination, language and sphincter control) and it is considered as more disabling not traumatic disease of young population in the world....

 Open Access DOI:10.23937/2572-3235.1510106

Radon Gas Potential Hazards Awareness among Undergraduate Students and Staff of a College of Health Sciences in South-East, Nigeria

Victor Kelechi Nwodo, Innocent Chinweike Ezenma, Geofery Luntsi, Mathew Garba Abubakar, Maryrose Chiche Nwodo, Chiegwu Hyacenth Uche, Ezeigwe Chijioke Ogomegbuam E and Charles Ugochukwu Nwodo

Article Type: Original Research Article | First Published: 2023/05/18

Radon is a noble radioactive gas that is considered one of the most significant indoor air pollutants associated with lung carcinoma when there is exponential dose inhalation and arithmetically depends on the concentration and duration of exposure. There is a paucity of documented research on knowledge and awareness of radon gas and associated potential radiological hazards among students and staff of the College of Health Sciences, Nnamdi Azikiwe University Awka, Nigeria. ...