Open Access DOI:10.23937/2469-567X/1510004
Hepatocellular Carcinoma in HIV-Infected Patients: Clinical Characteristics and Prognostic Factors
Antonio Diaz-Sanchez, Pilar Miralles, Ana Matilla, Teresa Aldamiz-Echevarria, OscarNunez Ana Carrero, Beatriz Merino, Cristina Diez, Rafael Banares, Gerardo Clemente and Juan Berenguer
Article Type: Research Article | First Published: December 26, 2014
We analyzed 53 HIV-infected patients with hepatocellular carcinoma (HCC) diagnosed at our institution from 1998 to 2012. All patients were coinfected with hepatitis virus (77% HCV; 12% HBV; 11% HCV+HBV), and 95% had liver cirrhosis. HCC was diagnosed under surveillance in 41% of patients. Potentially curative therapy was given to 32% of patients and palliative therapy to 30% patients. Median survival was 2 months in those diagnosed from 1998 to 2005, and 11 months in those diagnosed from 2006 to...
Open Access DOI:10.23937/2378-346X/1410003
The Superhero Drugs for Choroidal Neovascularization; Anti-VEGF Agents
Abdullah Ozkaya
Article Type: Editorial | First Published: October 29, 2014
A decade ago, the treatment of choroidal neovascularization (CNV) secondary to various macular diseases like age related macular degeneration, pathologic myopia, and angioid streaks was a crucial challenge. Laser photocoagulation could might be performed for juxtafoveal and extrafoveal CNVs and different surgical treatment options like macular translocation surgery and subretinal CNV excision were available. Th published studies usually were about neovascular age-related macular degeneration (nA...
Open Access DOI:10.23937/2377-9004/1410018
Management of Early Pregnancy Failure in a Patient with Pancytopenia
Diana Cholakian and Jenell Coleman
Article Type: Case Report | First Published: December 08, 2014
The safest and most effective therapy for an early pregnancy failure in women with pancytopenia is unknown. Here, we present a case report of a patient diagnosed with a 10-week embryonic demise who had a rare hematologic disorder called TnPolyagglutination syndrome that caused pancytopenia. The patient was offered expectant, medical, or surgical management, and she chose outpatient vaginal misoprostol. A week later, the patient presented to the emergency room with a septic abortion. She was give...
Open Access DOI:10.23937/2377-9004/1410017
Is Single Incision Laparoscopy A Feasible Alternative for Advanced Ovarian Cancer Approach? A Case Report and Literature Review
Marina Fistarol, Paula Guastaferro Magalhaes, Paola Gaston Giostri, Admario Silva Santos Filho, Augusto Henriques Fulgencio Brandao and Mauricio Bechara Noviello
Article Type: Case Report | First Published: December 08, 2014
Single Incision Laparoscopy (SIL) is a promising technique in the context of minimally invasive surgery, since it might improve cosmesis and cause less tissue trauma, if compared to multiple incision laparoscopies. Recent studies have shown its feasibility and safety for the approach of benign diseases. In this article, we report four cases of advanced ovarian cancer, addressed through SIL, with the purpose of fast diagnosis and recovery, allowing prompt onset of chemotherapy....
Open Access DOI:10.23937/2377-9004/1410016
An Unusual Cause of Transıent Fetal Ascıtes: Fetal Ovarıan Cyst Rupture
Demirpence S
Article Type: Case Report | First Published: December 07, 2014
Background: Ovarian cysts can be diagnosed prenatally and in case of persistence are found in newborns. Most resolve spontaneously, although in a small proportion of cases they can persist and be symptomatic. Fetal ascites may be due to immune or non immune hydrops fetalis or to a series of locoregional problems However, it can be an isolated finding rarely. Case: In this case we reported an isolated fetal ascites case that was caused by fetal ovarian cyst rupture. Conclusion:Fetal hydrops may b...
Open Access DOI:10.23937/2378-3516/1410005
The Differential Diagnosis of Asthma: Endobronchial Pulmonary Mesenchymoma
Mehmet Unlu, Pinar Cimen, Nuran Katgi and Salih Zeki Guclu
Article Type: Case Report | First Published: December 06, 2014
A variety of airway tumours are reported to manifest with symptoms similar to those of asthma and may cause delays in exact diagnosis because of the increase in size at a slow rate. Pulmonary endobronchial mesenchymoma is one of the slow growing tumours which is associated with symptoms or signs of airway obstruction mimicking asthma. So, patients with chronic symptoms suggestive of asthma, poor response to asthma medications, and frequent exacerbations should be evaluated for endobronchial mese...
Open Access DOI:10.23937/2378-3664/1410004
Reliability for Drug Targeting In Cancer Treatment through Nanotechnology (A Psychometric Approach)
Nader Ebrahimi and Ali Mansoori G
Article Type: Research Article | First Published: November 28, 2014
The primary focus of the nanotechnology therapeutic approaches has been on early disease detection, drug discovery and monitoring, controlled release of therapeutic agents, and targeted drug delivery. Targeted drug delivery system requires more research including statistical modelling to establish the reliability in success of drug targeting. This part of every nanotechnology therapeutic approach is especially fundamental for reaching stronger therapeutic effects with lower side effects....