Open Access DOI:10.23937/2469-570X/1410010

The Role of Mesenchymal Stem Cells in Diabetes Mellitus

Negar Azarpira, Maryam Kaviani and Saeede Salehi

Article Type: Research Article | First Published: July 02, 2015

Diabetes mellitus is a disease characterized by progressive destruction of the beta cells in the pancreatic islets of Langerhans. The current primary treatment is changing the life style and insulin injection. However, this therapy cannot provide sustained physiological glycemic control. Pancreas or islet cell transplantation would be the preferred treatment options. However, the lack of donor tissue immunoincompatibility, cell rejection and using long term immunosuppression are the major barrie...

 Open Access DOI:10.23937/2377-9004/1410045

Sclerosing Stromal Tumor of the Ovary in Postmenopausal Women: A Report of Two Cases

Chae Min Lee, Soyi Lim, Hyun Yi Cho, Seung Yeon Ha and Jin Woo Shin

Article Type: Case Report | First Published: June 19, 2015

Sclerosing Stromal Tumor (SST) was first delineated as a distinct ovarian sex cord stromal tumor in 1973 by Chalvardjian and Scully. It is a benign neoplasm, distinguished from other ovarian stromal tumors by the production of collagen and a pseudolobular pattern, and it tends to occur in the second and third decades of life in diagnosed patients. We discovered two rare cases of SST in postmenopausal women which are the topic of this report. These case studies are accompanied by a brief review o...

 Open Access DOI:10.23937/2377-9004/1410044

Fertility Sparing Surgery for Management of Serous Cystadenoma: Surgical Technique and Follow Up

Islam Fahmi, Mili Thakur, Ahmed Abdelaziz, Mohammed Ashraf and Mostafa I. Abuzeid

Article Type: Case Report | First Published: June 14, 2015

Ovarian cysts are commonly encountered adnexal masses by gynecologists, with a reported incidence of 5-15% of all reproductive age women. Large ovarian cysts are usually treated by surgical excision with cystectomy or oophorectomy. Laparoscopic ovarian cystectomy in large ovarian cysts has been underutilized. This report discusses the surgical technique of fertility sparing laparoscopic cystectomy for serous cystadenoma and subsequent follow up of these patients....

 Open Access DOI:10.23937/2377-9004/1410043

Extensive Hemorrhage during C-section of a Placenta Percreta with Bladder Invasion - Case Report

Rodrigo Dias Nunes, Djulie Anne de Lemos Zanatta and Natalia Vidal Lucena

Article Type: Case Report | First Published: June 08, 2015

Morbidly Adherent Placenta is a clinical condition where the placental tissue implants abnormally to the myometrium. In rare situations, the placenta can pass through the myometrium and invade organs surrounding the uterus; this is referred to as Placenta Percreta. This high morbidity condition can lead to a massive hemorrhage during surgery along with other various complications. We report a case of a 35 year old woman with no previous diagnosis of Placenta Percreta. During C-section, extensive...

 Open Access DOI:10.23937/2378-2951/1410036

Non-Invasive Assessment of Cardiac Autonomic Functions in Healthy Young Adults in Ile-Ife, South-Western Nigeria

Oluwadare Ogunlade, Abiodun O Ayoka, Anthony Akintomide, Rufus Ojo Akomolafe, Olumide S Akinsomisoye and David Oyewusi Oyebola

Article Type: Research Article | First Published: June 10, 2015

Background: This study assessed the responses of Blood Pressure (BP) and Heart Rate (HR) to change of posture, Sustained Handgrip (SH),deep breathing(DB) and Valsalva manoeuvre (VM) in order to determining the normal limits and pattern of Autonomic Cardiovascular Indices (ACI) among healthy young adults. Methods: Two hundred and four volunteer (98 men and 106 women) aged 18-40 years (mean, 22.45 +/- 4.86 years) participated in the study. After excluding systemic diseases by clinical evaluation, ...

 Open Access DOI:10.23937/2469-5718/1510011

Feasibility of Focused Cardiac Ultrasound in Pre-participation Screening

Miriam L. Fishman, Jennifer Shea, Brian G. Choi and Allen J. Solomon

Article Type: Original Research | First Published: May 29, 2015

Objective: Current American Heart Association (AHA) guidelines for pre-participation athletic screening recommend a 12-point history and exam to minimize the risk of sudden cardiac death. We tested the hypothesis that focused cardiac ultrasound (FCU) performed and simultaneously interpreted by a cardiologist using a handheld ultrasound device would be a feasible addition. Methods: We performed pre-participation screening according to AHA recommendations on high school athletes in a multi-purpose...

 Open Access DOI:10.23937/2377-4630/2/3/1031

Aminophylline does not Prevent Postdural Puncture Headache in Caesarean Section

Ismail Sirit, Ibrahim Ozturk, Dilek Yazicioglu

Article Type: Original Research | First Published: June 20, 2015

We aimed to investigate that whether intraoperative intravenous aminophylline is effective for prevention of postdural puncture headache after caesarean section or not. Materials and method: Records of patients who underwent caesarean section between January, 2013 and November, 2013 with spinal anesthesia were examined retrospectively. Patients older than 18 were included in the study. Failed and conversion to general anesthesia was the exclusion criteria....

 Open Access DOI:10.23937/2378-3656/1410041

Challenges of Fertility Sparing Ovarian Surgery Imposed by Krukenberg Tumors in Pregnancy

Michael H. Bloch, Ramey Z. Elsarrag, Mazin Z. Elsarrag and Sana M. Salih

Article Type: Case Report | First Published: June 29, 2015

Fertility sparing surgery is advocated for reproductive-age women with benign and borderline ovarian tumors. The hormonal milieu of pregnancy may, however, complicate the decision making process. The patient presented in the third trimester with a rapidly growing tumor that was diagnosed as benign steroid cell tumor by intraoperative frozen section. Fertility-sparing surgery with right oophorectomy and partial left oophorectomy was performed....

 Open Access DOI:10.23937/2378-3656/1410040

Acute Ovarian Insufficiency and Uterine Infarction Following Uterine Artery Embolization for Postpartum Hemorrhage

Sarah Z. Elsarrag, Abigail R. Forss, Susan Richman and Sana M. Salih

Article Type: Case Report | First Published: June 29, 2015

Uterine artery embolization for intractable postpartum hemorrhage saves lives while preserving fertility. The procedure-related risks of uterine infarction and ovarian insufficiency are rare. A primparous patient underwent bilateral internal hypogastric artery embolization to control severe postpartum hemorrhage following primary cesarean section. The bleeding continued, and a repeat aortogram demonstrated significant filing of the uterus from an anomalous proximal take off of the right uterine ...

 Open Access DOI:10.23937/2469-570X/1410009

Dental Stem Cells Characterization and Bone Regenerative Potential in Oral Medicine

Ricardo Rodrigues, Barbara Viana, Ivo Vieira, Joao Tavares, Renato Lobo, Ana Portela and Mario Vasconcelos

Article Type: Review Article | First Published: June 02, 2015

The oral cavity has proven to be an important reservoir of stem cells with the advantage of being a non-invasive source. These cells potential for maxillo-facial bone regeneration has been well documented throughout the last five years. This article aims at reviewing and discussing the different types of dental stem cells available in the oral cavity, their lineage characterization and potential applications in oral medicine; cell collection, isolation and preservation; bone regenerative potenti...