Open Access DOI:10.23937/2572-3235.1510111
Two Needles and Ten Minutes to Get the Patient Back on Her Feet and Allow Her to Sit at Will
Devara Anil Kashi Vishnuvardhan, Sandeep Botcha, K. Venkata Suman, K. Venkateswarlu and P. Vijayalakshmi
Article Type: Case Report | First Published: 2023/08/11
A 46-year female with long-standing disabling low backache with pain radiating to the right lower limb, pain at tail bone not allowing her to sit, sleep and stand for the last 3 months with acute exacerbation since 3 days were diagnosed as degenerative lumbar disc disease with right L5/S1 radiculopathy and coccydynia not responding to medical management and treated with minimally invasive procedures - CT guided ganglion impar block. CT showed a right lumbar nerve root block at L5/S1 level, leadi...
Open Access DOI:10.23937/2378-3419/1410184
Intercalary Endoprosthetic Reconstruction for Long Bone Defects of the Lower Extremity
Jennifer A Bell, MD, Brandon S Gettleman BS, Alexander B Christ, MD, Caroline E Vonck, MD and Lawrence R Menendez, MD
Article Type: Retrospective Review | First Published: 2023/08/12
Modular intercalary endoprostheses is a potential reconstructive option infrequently studied for diaphyseal defects of long bone. The purpose of this study was to examine the 1) Method of failure rate of revision after reconstruction with modular intercalary endoprostheses based on the anatomic site and 2) Describe the functional status of the patient and use of assistive devices with ambulation....
Open Access DOI:10.23937/2469-5831/1510051
Biostatistical Methodologies in Clinical Trials: An Overview of Recent Developments and Pitfalls
Sagar Kumar Patel, Rachna Patel and Sandeep Bolla
Article Type: Review Article | First Published: August 16, 2023
Biostatistical analysis has emerged as one of the most crucial applications for clinical trial systems. The relevance of statistical analysis in clinical trials cannot be overstated in the advancement of novel pharmaceuticals and therapeutics. Data volumes, including effectiveness and safety summaries, are produced throughout the process of developing and approving novel medicines....
Open Access DOI:10.23937/2572-4010.1510046
Perceptions of Nurses on Obesity Treatment Options
Thomas Boansi Gyamerah, Kwadwo Ameyaw Korsah, Gloria Achempim-Ansong, Bonney Osei, Samson Kofie, Samuel William Dodoo and Samuel Darko Opoku
Article Type: Original Article | First Published: 2023/08/10
Obesity is described as deviation from normal fat accumulation which endangers the health of an individual. The Body Mass Index (BMI) is normally used to indicate whether an individual is obese or otherwise. Different options of treatments are used in obesity reduction. Nurses play a significant role in providing medical care in obesity reduction....
Open Access DOI:10.23937/2378-2951/1410279
Atrial Flutter as the Primary Manifestation of Lupus Flare Up
Varinder Bansro, MD, Tekabe Birhane, MD, Marvi Gurbakhshani, MD, Fregenet Gichamo, MD and Uchenna Unamba MD
Article Type: Case Report | First Published: 2023/08/07
This review article explores the association between atrial flutter and systemic lupus erythematosus (SLE). Atrial flutter, a common cardiac arrhythmia, has been recognized as a potential cardiovascular manifestation of SLE, a chronic autoimmune disease. The abstract summarizes the current literature on the epidemiology, pathophysiology, clinical presentation, diagnosis, and management of atrial flutter in patients with SLE. Furthermore, it highlights the challenges in diagnosing and treating th...
Open Access DOI:10.23937/2572-3987.1510029
Effect of Overlapping Insulin Glargine Administration in Decreasing Incidence of Hyperglycemia after Discontinuation of Intravenous Insulin Infusion
Jillian B Searle, PharmD, Veronika Latawiec, PharmD, Micaela Carroll Powner, PharmD, BCPS, Andrea Winston, PharmD, BCACP and Dorothy Wakefield, M.S., PStat
Article Type: Original Article | First Published: 2023/08/06
The study purpose was to assess the incidence of hyperglycemia in patients being transitioned from an IV infusion to subcutaneous (SC) insulin. Study staff evaluated whether overlapping SC with IV insulin decreased the incidence of hyperglycemia....
Open Access DOI:10.23937/2378-3672/1410069
Recent Application of Nanotechnology for Cancer Immunotherapy and Its Future Prospects
Ashok H Akabari, Sagarkumar Patel, Nikita Vaghela, Vinod Ramani and Dhiren P Shah
Article Type: Research Article | First Published: 2023/08/05
Nanotechnology means measurements estimated by nanometers or one-billionth of a meter- - to make structures, medical devices, gadgets and frameworks for medical, clinical and other uses, such as disease diagnosis. Cancer immunotherapy uses medications or drugs to help a patient's immune system fight cancer, as opposed to chemotherapy, which uses drugs to directly kill cancer cells, according to the National Cancer Institute (NCI)....
Open Access DOI:10.23937/2378-3656/1410431
Deep Vein Thrombosis with Concomitant Cellulitis in a 47-Year-Old Filipino Female
Lea Fatima B Hingpit, MD and Lalaine R Visitation, MD, FPDS
Article Type: Case Report | First Published: 2023/07/31
Deep Vein Thrombosis (DVT) occurs when there are clots in the deep veins of the body, accounting for the majority of venous thromboembolism (VTE) cases. Half of the cases may report symptoms of pain, swelling, warmth and discoloration or redness which may be similar to cellulitis. Here we report a 47-year-old Filipino female who presented with bullae on her left leg, associated with pain, swelling and erythema which improved with anticoagulants and antibiotics....
Open Access DOI:10.23937/2378-3656/1410430
A Rare Case of Acute Ischemic Stroke Following Russell's Viper Snake Bite
Addepalli Naga Sowmya, Addepalli Yamini and M Nagarjuna
Article Type: Case Report | First Published: 2023/07/31
Ischemic stroke following a snakebite is a rare complication. We report a case of a 49-years-old male who developed weakness of right upper and lower limb slurring of speech with facial asymmetry following Russell's viper bite. Magnetic resonance imaging of brain revealed infarct in the left middle cerebral artery territory. The possible mechanisms for cerebral infarction in this scenario are discussed, which were hypotension causing watershed infarcts due to hypovolemia....