Open Access DOI:10.23937/2378-3656/1410067
Interferon and Ribavirin-Induced Oral Hyperpigmentation in Two Taiwanese Patients: Case Report and Literature Review
Yu-Jong Weng and Min-Fu Tsan
Article Type: Case Report | First Published: November 01, 2015
A variety of medications such as non-steroidal anti-inflammatory drugs, anti-malarials, amiodarone, cytotoxic drugs, tetracyclines, heavy metals, and psychotropic drugs, may cause cutaneous hyperpigmentation. Recently, hyperpigmentation of the tongue and oral mucosa have also been reported in patients with hepatitis C virus (HCV) infection who were being treated with either short acting IFN or long acting polyethylene glycol-conjugated IFN (PEG-IFN) combined with ribavirin (RBV). The IFN or PEG-...
Open Access DOI:10.23937/2378-3656/1410066
A Case of Acute Pancreatitis without Enzyme Elevation - A Rare Presentation of a Common Condition
Edupuganti Mohan Mallikarjuna Rao, Vjayanthi Ganga, Michael Moore and Srikanth Medarametla
Article Type: Case Report | First Published: October 30, 2015
Acute Pancreatitis is most often diagnosed based on a threefold elevation of amylase and lipase in the appropriate clinical setting. Very rarely the enzyme levels may be completely normal casting a doubt on the diagnosis. We present a case of acute pancreatitis without elevation of enzymes, review the literature, enlist the situations where serum enzyme levels are not elevated, discuss the diagnostic criteria, enzyme kinetics and briefly delve into the newer biomarkers of acute pancreatitis....
Open Access DOI:10.23937/2377-4630/2/4/1035
Severe Respiratory Suppression Secondary to Buprenorphine Treated with Volume Assured Pressure Support (VAPS)
Robert J Farney, Boaz Markewitz, Amanda M McDonald and Jill Rhead
Article Type: Case Report | First Published: November 16, 2015
The optimal therapy of chronic opioid induced sleep disordered breathing (SDB) is unclear. Supplemental oxygen may potentially prolong central apneas and increase respiratory suppression. Continuous positive airway pressure (CPAP) is generally ineffective or may even augment central apneas. Therapy with an Adaptive Servo-Ventilation (ASV) device is the most successful option for most etiologies of central apnea including opioids, but we have observed a subpopulation with OISDB that do not respon...
Open Access DOI:10.23937/2377-4630/2/3/1034
The Effect of Dexmedetomidine and Propofol on Oxidative Stress Parameters during Lower Extremity Surgery: A Prospective Randomized Trial
Safinaz Karabayirli, Ismail Uras, Cemile Koca, Merve Ergin, Ruveyda Irem Demircioglu, Bunyamin Muslu
Article Type: Original Research Article | First Published: September 12, 2015
Tourniquets are routinely applied during lower extremity surgery in order to reduce bleeding during surgery, provide better surgical conditions and consequently to shorten the duration of the operation. However, an inflammatory response is often activated by tourniquet application, leading to prolonged ischemia and reperfusion; consequently, organ damage such as acute lung injury may occur. Muscular ischemia causes hypoxic cellular changes and anaerobic glycolysis, and its neutrophil activation ...
Open Access DOI:10.23937/2377-9004/1410064
Left Vaginal Obstruction and Complex Left Uterine Horn Communication in a 12 Year Old Female
Barry E. Perlman, Amy S. Dhesi, Gerson Weiss
Article Type: Case Report | First Published: October 29, 2015
Obstructive Mullerian duct anomalies are an infrequently encountered clinical problem. The use of imaging and surgical exploration allowed for diagnosis and treatment of symptoms of a complex obstructive mullerian anomaly. We present a case of a 12 year old female with a history of intermittent lower abdominal pain and absent left kidney who was found to have an obstructed left vagina and complex left uterine horn communications resulting in hematocolpos, hematometra, and endometriosis....
Open Access DOI:10.23937/2377-9004/1410063
Turner Syndrome and Infertility: A Review of Literature
Emine Demirel, Emre Ekmekci, Zeynep Soyman and Sefa Kelekci
Article Type: Review Article | First Published: October 28, 2015
Fertility of women with Turner Syndrome is now being more interested due to the new improvements in assisted reproductive techniques. Turner Syndrome is characterized by the premature atresia of ovarian follicules. Atresia starts at intrauterine period and continues till all ovarian follicules go to atresia. The time of this period changes from patient to patient. Also Turner Syndrome is related with higher risks in pregnancy. These include higher incidence of spontaneous abortion, fetal anomaly...
Open Access DOI:10.23937/2377-9004/1410062
Placental Abruption Diagnosed by the Lab Technician
L MacDonald, F Waterson, S Marshall and A Cope
Article Type: Case Report | First Published: September 30, 2015
Placental abruption is the separation of the placenta from the uterus. Diagnosis of placental abruption is largely a diagnosis of exclusion and ultrasound is not diagnostic. A case of a placental abruption diagnosed by the presence of two blood types in the group and save sample is presented. A thorough search of the relevant databases would suggest that this is the first reported case of such....
Open Access DOI:10.23937/2377-9004/1410061
Primary Umbilical Endometrioma: A Case Report
Lim Leek Mei and Mickael Hoong Farn Weng
Article Type: Case Report | First Published: September 30, 2015
We report a case of primary umbilical endometrioma. She was a 41year old lady, para 1+1 with a background history of type2 diabetes mellitus, hypertension and a previous uneventful Caesarean section in 2005. She was subfertile since then. She presented with scanty painless bleeding from the umbilicus for past 5 months which coincided with her menses. The bleed would start a few days before her menses and ceased by day two, in small amount and painless. Her cycles were regular with normal flow a...
Open Access DOI:10.23937/2572-4053.1510006
Nightmares and Associations with Sleep Quality and Self-Efficacy among University Students
Angelika A. Schlarb, Isabel Bihlmaier, Martin Hautzinger, Marco D. Gulewitsch and Barbara Schwerdtle
Article Type: Research Article | First Published: October 27,2015
Sleep problems are a common complaint among adults. In university students international studies showed prevalence rates between 4.7 and 36.2% for sleep difficulties and 2-3% of students report nightmares. Previous studies show that nightmares are often associated with insomnia and mental strain, but also with gender. The goal of this study was to outline nightmares, associations with sleep disturbances and mental strain as well as self-efficacy among university students. An amount of 2196 stude...