Open Access DOI:10.23937/2378-3656/1410078

Patellar Tendon Rupture. Repair with Suture Anchors and Percutaneous Reinforcement with Semitendinosus and Gracilis Tendons: Two Cases

Manuel Godino

Article Type: Case Report | First Published: December 22, 2015

Patellar tendon disruptions are relatively uncommon knee injuries compared to fractures, ligaments sprains, or meniscal tears [1]. These tears may be traumatic or they may occur spontaneously in patients with other underlying diseases such as diabetes mellitus, rheumatoid arthritis, steroid medication or kidney failure. MRI can also be useful, by providing additional information such as the location of the rupture. We reported one case of neglected patellar disruption and the other case was trau...

 Open Access DOI:10.23937/2378-3656/1410077

Long-Segment Slide Tracheo-Bronchoplasty (LSTB) with Contralateral Lung Agenesis: Case Report and Review of the Literature

Daniel J. Weber, Mark D.Rodefeld, Bruce H. Matt and John W. Brown

Article Type: Case Report | First Published: December 18, 2015

The management of long-segment tracheal stenosis (LSTS) can be quite challenging, particularly in the presence of other pulmonary anomalies. We present a complicated case of LSTS and left bronchial stenosis in a 4-month-old infant with a congenitally absent right lung. This case emphasize that a slide tracheo-bronchoplasty (STB) in the setting of congenital absence of the contralateral lung is complicated but can be performed with reasonable results....

 Open Access DOI:10.23937/2378-3656/1410076

Hypothesizing Balancing Endorphinergic and Glutaminergic Systems to Treat and Prevent Relapse to Reward Deficiency Behaviors: Coupling D-Phenylalanine and N-Acetyl-L-Cysteine (NAC) as a Novel Therapeutic Modality

Kenneth Blum, Marcelo Febo, Claudia Fahlke, Trevor Archer, U Berggren, Zsolt Demetrovics, Kristina Dushaj and Rajendra D. Badgaiyan

Article Type: Hypothesis | First Published: December 17, 2015

In this hypothesis, we are proposing that the combination of D-Phenylalanine and N-acetyl-L-cysteine (NAC) - two substances that have never been utilized together - is an important advancement to treat Reward Deficiency Syndrome (RDS) [1]. The key motivation for this notion is that the combination will have synergistic attributes to induce dopamine release as well as dopamine stabilization at the brain reward circuitry via different mechanisms. We hypothesize that preferential release of Dopamin...

 Open Access DOI:10.23937/2469-570X/1410013

Enhancing the Potency of Mesenchymal Stem Cells for Tissue Regeneration

Sylvia Muller, Kenny Dalgarno, Anne Dickinson, Xiao-nong Wang and Lindsay Nicholson

Article Type: Short Review | First Published: November 27, 2015

Mesenchymal stem cells (MSCs) are adult stromal cells with multi-lineage differentiation potential and immunomodulatory properties. They can be isolated relatively easily from several tissues, including bone marrow and adipose tissue and can be expanded ex vivo to yield the large numbers required for a therapeutic dose. As such, MSCs are considered a promising cell source that can be used in cellular therapy for a wide range of diseases, including bone and cartilage defects. However, despite the...

 Open Access DOI:10.23937/2469-5718/1510029

Dietary Iron Intake and Hemoglobin Concentration in College Athletes in Different Sports

Takako Fujii, Yuka Okumura, Etsuko Maeshima and Koji Okamura

Article Type: Research Article | First Published: December 11, 2015

Iron-deficiency anemia is relatively prevalent among endurance athletes. It is therefore recommended that athletes consume a greater amount of iron. Resistance exercise has been shown to alleviate anemic symptoms, suggesting that the prevalence of anemia may vary among athletes that participate in different sporting events and that their iron requirements may differ according to their sports. The present study investigated the relationship between iron intake and anemia in college athletes in di...

 Open Access DOI:10.23937/2469-5718/1510028

Preliminary Study on Prevalence of Urinary Incontinence in Iranian Female Athletes

Behnoosh Vasaghi-Gharamaleki and Sedigheh Ostad-Rahimi

Article Type: Original Article | First Published: December 04, 2015

Research carried out over the past few decades has shown that urinary incontinence is observed among physically active women, including those involved in professional high impact sports. The purpose of this preliminary study was to investigate the prevalence of stress urinary incontinence (SUI) and assess its risk factors among Iranian female athletes. A total of 195 volunteers comprising women athletes aged between 16.5 and 32.5 years....

 Open Access DOI:10.23937/2377-9004/1410067

Growing Teratoma Syndrome Concurrent with Pregnancy: A Case Report and Literature Review

Aki Tanaka-Murakami, Masakazu Abe, Yuka Kasamatsu, Nobuhiro Kado, Shiho Kuji, Nobutaka Takahashi, Munetaka Takekuma and Yasuyuki Hirashima

Article Type: Case Report and Literature Review | First Published: November 30, 2015

Growing teratoma syndrome (GTS) is a rare disease characterized by the appearance of benign metastatic lesions during or after chemotherapy for germ cell tumor. Complete surgical resection is important for the diagnosis and cure of GTS. We encountered a patient with a suspected GTS during her second pregnancy and childbirth; 4 years later, radical surgery confirmed the diagnosis. A tumor that was suspected to be GTS was observed in a 31 year old 2 para woman immediately after the completion of f...

 Open Access DOI:10.23937/2377-9004/1410066

Familial Hypercholesterolemia and Pregnancy: Risk and Management

Roberta Mombelli and Giuliana Mombelli

Article Type: Review Article | First Published: November 18, 2015

Familial hypercholesterolemia (FH) is a dominantly inherited disorder present from birth with elevated levels of low-density lipoprotein (LDL) cholesterol and increased risk for premature coronary heart disease (CHD) with clinical manifestation between the first and the fourth decades of life. Although statins are the most effective therapy for individuals with FH the use of statins is contraindicated during pregnancy. For this reason, before of a pregnancy the lipid-lowering drugs are discontin...

 Open Access DOI:10.23937/2377-9004/1410065

VIA and Challenges of a Single Visit Approach in Malawi

Haeok Lee, Mary Sue Makin, Jasintha T Mtengezo and Address Malata

Article Type: Case Report | First Published: November 01, 2015

Cancer of the cervix is the most common cancer in women in sub-Saharan Africa. This is a report of the experience of a 25 year-old HIV negative woman with five children who was detected with a precancerous lesion with VIA at a local health facility. She was referred for post-VIA treatment at another facility 60 Km away. She traveled all day for her follow-up treatment and spent all her money to get there so that she had none remaining to pay for food or her return bus fare. This case study point...

 Open Access DOI:10.23937/2572-4193.1510010

Endoscopic Transcanal Cartilage Myringoplasty for Repair of Subtotal Tympanic Membrane Perforation: A Method to Avoid Postauricular Incision

Khaled M Mokbel, Waleed Moneir, Hossam Elsisi and Ahmed Alsobky

Article Type: Original Article | First Published: December 28, 2015

Our aim is to evaluate transcanal endoscopic approach in repair of subtotal tympanic membrane perforation in a trial to prevent conventional postaural approach. Our study was done in 80 patients with unilateral dry subtotal tympanic perforations. They were 44 males and 36 females. Their ages ranged from 18-50 years with mean of 33 years. Autograft thin (0.2 mm) auricular cartilage shield was used to repair tympanic membrane perforation. Patients were divided into two groups according to the appr...