Open Access DOI:10.23937/2378-2951/1410069
Left Ventricular Assist Device Placement through Left Thoracotomy in Difficult Scenarios
Lyndsay M. Mueller, Samuel H. Cho, Timothy Fritz and Asghar Khaghani
Article Type: Case Report | First Published: January 18, 2016
Standard surgical approach to the implantation of a Left Ventricular Assist Device (LVAD) is through a median sternotomy. The inflow cannula is attached to the apex of the left ventricle, while the outflow graft is usually attached to the ascending aorta. We present 2 patients with prohibitive chest wall abnormalities who underwent left thoracotomy for LVAD placement, and the outflow graft alternatively attached to the descending aorta....
Open Access DOI:10.23937/2378-3419/3/1/1042
Breast Cancer in Surgical Site: Unusual Presentation of an Ectopic Milk Line Malignancy
Zsolt Varga, Miklos Torok, Eva Sebo, Judit Toth and Dezso Toth
Article Type: Case Report | First Published: January 30, 2016
A 56-year old woman with history of laparoscopic cholecystectomy was referred to outpatient clinic 3 years after the operation with a non-healing reddish lump in the surgical scar. The lesion was situated at the site of the right subcostal port, in the medioclavicular line, below the ribcage. Local excision was performed and histological evaluation revealed poorly differentiated adenocarcinoma, which was thought to be metastatic. After multiple recurrences, appearance of an axillary lymph node m...
Open Access DOI:10.23937/2378-3419/3/1/1041
The Usefulness of Nutritional Index CONUT for Risk Assessment and Prognosis after Pancreaticoduodenectomy
Shinichi Sekine, Takuya Nagata, Tomoyuki Okumura, Shunsuke Kawai, Katsuhisa Hirano, Takeshi Miwa, Makoto Moriyama, Hirofumi Kojima, Isaya Hashimoto, Kazuto Shibuya, Shozo Hojo, Isaku Yoshioka, Koshi Matsui, Shigeaki Sawada and Kazuhiro Tsukada
Article Type: Original Research | First Published: January 30, 2016
Pancreaticoduodenectomy (PD) is a highly invasive surgery. Therefore, assessment of pre-operative nutritional status may contribute to the postoperative course. Patients (n = 116) who had undergone PD were included in this study. We evaluated the usefulness of the body mass index (BMI), prognostic nutrition index (PNI), and controlling nutritional status score (CONUT) for evaluating post-operative complication risk by examining the relationship between pre-operative nutritional status and the oc...
Open Access DOI:10.23937/2378-3664/1410017
Ovarian Cancer Treatment by Suicide Gene Therapy: Beauty of Nanotechnology in Medicine
Abhimanyu Thakur, Mahadi Hasan MA Shahed, Aishwarya Roy and Nabila Sayed
Article Type: Short Commentary | First Published: February 09, 2016
There has been a global interest worldwide in the recent trend of medical researches, which is basically a merge up between basic biology and engineering tools/technology. Imaging, microfluidics, nanofluidics, surface plasmon resonance (SPR) sensor systems, etc. are the widely used engineering tools in medical researches and has given effective clinical results. The most effective and widely used technology amongst these would be nanotechnology which employs methods like nano drug delivery, nano...
Open Access DOI:10.23937/2378-3664/1410016
Studying Complex Interaction of B2H4 with HOR(R = H, CH3) and Nhn(CH3)3-N (N = 0-3) Molecules
Reza Tayebee and Abedien Zabardasti
Article Type: Research Article | First Published: February 02, 2016
Borane complexes are extensively studied and have even been the subject of Nobel Prize by Brown [1]. Many scientific data exist that have shown that boron is an essential microelement in animal cells. With the knowledge that borate linkages function in cell-to-cell adhesion, it has been hypothesised that boronates target structural glycoproteins located along the cytoskeletonplasma membrane-cell wall assembly....
Open Access DOI:10.23937/2469-584X/1510012
Are Patients Hospitalized with Cirrhosis and Ascites Receiving Appropriate Diagnostic Paracentesis?
Harith Baharith, Yuhong Yuan and Marco Puglia
Article Type: Research Article | First Published: February 16, 2016
Ascites is the most common complication of cirrhosis, and is associated with increased mortality. Diagnostic paracentesis is recommended for patients who are admitted to the hospital with ascites. However, it is unknown if diagnostic paracentesis in Canadian teaching hospitals are done according to recommended guidelines. We analyzed the rate of paracentesis, determined barriers for not performing paracentesis and the association of not performing paracentesis with mortality....
Open Access DOI:10.23937/2469-584X/1510011
Eradication of Helicobacter Pylori Infection: Past, Present and Future
Baryshnikova NV, Uspenskiy YP and Suvorov AN
Article Type: Review Article | First Published: January 26, 2016
This review is a comprehensive summary of different variants of anti-Helicobacter pylori therapy from past strategies to the current state of the art. Nowadays we see a progressive decreasing of eradication rate in many countries in case of use standard triple therapy. It can be associated with high clarithromycin resistance of Helicobacter pylori. Gradual increase in number of the used antibiotics, the increase in duration of treatment, use of new antibacterial compounds and schemes of treatmen...
Open Access DOI:10.23937/2469-584X/1510010
Advances and Controversies in the Management of Locally Advanced Gastro-esophageal Adenocarcinoma
Hirva Mamdani, Kenneth A Kesler and Shadia I Jalal
Article Type: Review Article | First Published: January 09, 2016
Esophageal adenocarcinoma (EAD) has been recently described as 'the silent epidemic' because of its rapidly rising incidence. Two-thirds of patients with esophageal adenocarcinoma present with locally advanced disease. In spite of recent advances in cancer therapy, the treatment of locally advanced esophageal and gastroesophageal junction (GEJ) adenocarcinoma remains challenging. Current standard of care for fit patients with locally advanced esophageal adenocarcinoma is trimodality therapy with...