Open Access DOI:10.23937/2377-9004/1410071
Broad Ligament Hernia after Cesarean Section
Christopher M Tarney, Johnnie Wright Jr and Karen Wilson
Article Type: Case Report | First Published: January 29, 2016
Small bowel obstruction is rare after cesarean section but can become a surgical emergency. As the rate of cesarean deliveries increases, the frequency of complications will likely increase. A 26-year-old woman, gravida 3 para 2002, underwent emergent cesarean section at term for non-reassuring fetal status. The procedure was complicated by difficulty returning the uterus to the abdomen after exteriorization for hysterorrhaphy. She was readmitted and brought to surgery on postoperative day five ...
Open Access DOI:10.23937/2378-346X/1410047
Removal of Extruded Ex-Press Miniature Glaucoma Device in a Case with Ahmed Glaucoma Valve: A Case Report
Sinan Bilgin and Ozcan Kayikcioglu
Article Type: Case Report | First Published: January 31, 2016
Here, we report our experience with explanation of ex - press miniature glaucoma device which extruded due to conjunctival erosion in a case with Ahmed glaucoma valve implant. After explanation of the shunt, opening-insertion site on the cornea was covered with conjunctival autograft. Although transient hypotony and limited choroidal detachtment were observed in the first two days, no complications related to failure of Ahmed glaucoma valve occurred. Because of an increasing number of patients w...
Open Access DOI:10.23937/2378-346X/1410046
Novel Deletion in the CNNM4 Gene in Siblings with Jalili Syndrome
F Kiessling, D Mitter, T Langmann, D Muller and H Tegetmeyer
Article Type: Research Article | First Published: January 16, 2016
Different mutations in the CNNM4 (OMIM 607805) gene are known to cause Jalili syndrome (OMIM 217080) which is characterized by a combination of cone-rod dystrophy and amelogenesis imperfecta. In particular one homozygous missense mutation Leu438Profs*9 in exon 1 of the CNNM4 gene has been described in patients originating from the Kosovo. This mutation causes a frameshift and generates a new stop codon in the same exon. The two patients described here carry the same Leu438Profs*9 mutation in a h...
Open Access DOI:10.23937/2378-3419/3/1/1043
Developing Pathway Collection for Personalized Anti-cancer Therapy
Luminita Castillos and Anton Yuryev
Article Type: Research Article | First Published: February 01, 2016
We describe methodology for developing personalized anti-cancer drug therapy using pathway analysis. We successfully applied this methodology to treat several cancer patients that were terminally diagnosed by standard of care criteria at the hospital. Our approach consists of profiling patient tumor using gene expression microarray and calculating pathways responsible for the differential expression between tumor and normal control tissue....
Open Access DOI:10.23937/2378-3516/1410039
Electron Microscopic Analysis of Silicate and Calcium Particles in Cigarette Smoke Tar
R Steven Pappas, Mary M Halstead and Clifford H Watson
Article Type: Research Article | First Published: February 11, 2016
Scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDS) supplies information that is complementary to those data traditionally obtained using inductively coupled plasma-mass spectrometry for analysis of inorganic tobacco and tobacco smoke constituents. The SEM-EDS approach was used to identify select inorganic constituents of mainstream cigarette smoke "tar". The nature of SEM-EDS instrumentation makes it an ideal choice for microstructural analyses as it provides inform...
Open Access DOI:10.23937/2378-3516/1410037
Debilitating Disease in a Daring Child with Determined Parents - Impact on Survival
Marie Christy Sharafine Stephen, Eswaran Venkata Raman, Gnanam Aram and Anitha Kumar
Article Type: Case Report | First Published: February 02, 2016
Pompe disease is a rare and progressive lysosomal storage disorder, of autosomal recessive inheritance. Disease onset and progression range from early infantile onset which is fatal and rapidly progressive to the late onset formthatis slowly progressive, but leads to severe respiratory dysfunction and significant morbidity. Besides, scoliosis and other spine deformities cause substantial workload on the already compromised ventilation. This has a major impact on the quality of life and life-expe...
Open Access DOI:10.23937/2469-570X/1410025
CD271 Negative Human Dental Pulp Cells Yield Significantly More Adherent Colony Forming Cells than the Positive Phenotype
Matthew J Tomlinson, Elena A Jones, Peter V Giannoudis, Xuebin B Yang and Jennifer Kirkham
Article Type: Original Research | First Published: February 08, 2016
Cell surface markers for isolating proliferative human dental pulp stromal cells are currently lacking. Other tissues containing mesenchymal stromal cells have been studied in greater depth and candidate markers for cell isolation identified, one such marker being CD271. Previous reports suggest CD271 as a marker for isolating dental pulp stromal cells from rat incisors. We aimed to study the utility of CD271 as a marker for isolating human dental pulp stromal cells. CD271 positive cells from bo...