Open Access DOI:10.23937/2469-5750/1510024
Dry Eye Syndrome: What the Dermatologist Needs to Know
David M. Kleinman
Article Type: Short Review | First Published: April 21, 2016
It is very likely that dermatologists will see patients who have both skin concerns and concomitant dry eye syndrome. Over 25 million Americans have some form of dry eye, and symptoms related to dry eye are one of the leading causes of visits to ophthalmologists. Dry eye syndrome can often be easy to diagnose, and the first line of interventions are simple, low risk, and low cost. Specialists and subspecialists are generally averse to making medical recommendations outside their field of experti...
Open Access DOI:10.23937/2469-5750/1510023
Anti-Androgen Therapy in Female Adult Acne
Jing Gao and Anjali Mahto
Article Type: Review Article | First Published: April 20, 2016
Acne vulgaris is a multifactorial disease of the pilosebaceous unit as a result of androgen-induced increased sebum production, altered keratinisation, inflammation, and hair follicle bacterial colonisation by Propionibacterium acnes (P. acnes). The clinical features of acne include seborrhea, comedones, and papules and pustules. Nodules and cysts are seen in severe nodulocystic acne and scarring can follow. Acne can occur alone or with signs of hyperandrogenism such as hirsutism, alopecia and m...
Open Access DOI:10.23937/2469-5750/1510022
Folliculotropic Mycosis Fungoides: A Clinicopathological Study of a Series of 10 Cases
V Vergote, P Wolter, E Hauben and AM Busschots
Article Type: Case Report | First Published: April 13, 2016
Ten patients (8 male, 2 female) with a median age at diagnosis of 45 years were included. The median duration of the presence of skin lesions before diagnosis was 11 years. The most common sites of involvement were head and neck (80%), trunk and extremities (80-90%). Clinical features included patches and plaques, often associated with follicular prominence and alopecia, or comedo-like lesions, nodules and cysts. Fifty percent complained of pruritus. Histological findings included folliculotropi...
Open Access DOI:10.23937/2572-3286.1510009
Guillain-Barre Syndrome Associated with Cyclosporine A
Rizawati RI, Shamila K, Shafira MS and Ruslinda M
Article Type: Case Report | First Published: May 20, 2016
Guillain-Barre syndrome (GBS) is also known as an acute inflammatory demyelinating polyneuropathy (AIDP). It is an immune-mediated polyneuropathy commonly post-infectious in origin that presents with ascending weakness, loss of sensation and deep tendon reflexes resulting from demyelination of peripheral nerve. Drug-induced neuropathy has been describing before and remains a rare clinical entity. Development GBS after an episode of infections such as Campylobacter Jejuni, Epstein Barr Virus, and...
Open Access DOI:10.23937/2572-3286.1510008
A Review on the Potential Role of Vitamin D and Mineral Metabolism on Chronic Fatigue Illnesses
Anna Dorothea Hock
Article Type: Review Article | First Published: May 14, 2016
Vitamin D3-insufficiency/ deficiency is a common condition arising from prevalent indoor activities and use of sunscreens with high protection factor. Lacking sunlight is frequent in patients suffering from chronic fatigue syndrome (CFS), fibromyalgia (FMS), and myalgic encephalopathy (ME) probably because of fatigue-related reduction of outdoor activity, high premorbid engagement in professional or caring activities, and preceding stressful life events....
Open Access DOI:10.23937/2572-3286.1510007
Depression in Late-Life patients with End-Stage Renal Disease under Online-Haemodiafiltration is Associated with Low Social Support, Muscular Mass and Creatinine Serum Levels
Leonilde Amado, Veronica Poveda, Ricardo Ferreira, Nuno Ferreira, Vasco Miranda Laetitia Teixeira, Constanca Paul, Alice Santos-Silva and Elisio Costa
Article Type: Original Article | First Published: April 28, 2016
Patients with end-stage renal disease (ESRD) under dialysis showed a higher prevalence of depression, which is independently associated with non-adherence, hospitalization and mortality. We aimed to evaluate the prevalence of depression and associated variables, among ESRD late-life patients under online-haemodiafiltration (OL-HDF)....
Open Access DOI:10.23937/2469-584X/1510021
Deception in Crohn's Disease: A Case of Cryptogenic Multifocal Ulcerous Stenosing Enteritis
Huafeng Shen, David R Cave and Seymour Katz
Article Type: Case Report | First Published: April 21, 2016
Cryptogenic multifocal ulcerous stenosing enteritis is a rare idiopathic condition, characterized by multiple small intestinal fibrous strictures with superficial ulcerations. It typically has a chronic or relapsing clinical course and has been mainly reported from Asia and Europe. We report a case of cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) in a patient with chronic anemia with melena and intermittent abdominal pain. The clinicopathological features of CMUSE are different fro...