Open Access DOI:10.23937/2469-5734/1510028

Comparısıon Success Rate of Immedıate Implants at Fresh Extractıon Sockets and Conventıonal Implants

Elif Oncu

Article Type: Original Article | First Published: May 29, 2016

Immediate implant placement has gained popularity because it can reduce treatment time, number of surgeries and post-extraction bone loss. Following tooth extraction, socket area shows series of physiologic processes, during the recovery time that passes between tooth extraction and the placement of the implant, the majority of the amount of bone resorption and gingival remodeling is confirmed, which is usually the cause of biological, aesthetic and functional damage....

 Open Access DOI:10.23937/2572-3243.1510014

Medial Epicondylitis and Medial Elbow Pain Syndrome: Current Treatment Strategies

Christina Brady and Anil Dutta

Article Type: Review Article | First Published: June 03, 2016

Medial elbow pain is a common complaint in the active population. The most frequent muscular or tendinous condition to cause medial elbow pain is Medial Epicondylitis (ME). The disorder is classically described as Golfer's elbow due its association with elbow pain caused by excessive eccentric force across the common flexor origin encountered during the golf swing. In the working population, the condition is frequently associated with repetitive use and is seen in manual laborers who require for...

 Open Access DOI:10.23937/2572-3243.1510013

Regenerative Therapy in Osteoarthritis of the Knee

Jonathan Theo and Edward Pang

Article Type: Literature Review | First Published: May 21, 2016

Osteoarthritis (OA) is the most common joint disorder in the world. It commonly affects the knee and current treatment options are limited, focusing mainly on symptom relief. It is now known that OA is the result of both mechanical and biological events that disrupt anabolic and catabolic processes in the joint. Recently, research in regenerative therapies has been gaining interest because of its potential to restore normal structure and function following tissue injury. The goal is to use the b...

 Open Access DOI:10.23937/2378-3648/1410025

Sedaghatian-Type Spondylometaphyseal Dysplasia: A Case of Rapid Demise with Evidence of Myocardial Injury

Mehmet Sah Ipek and Alper Akin

Article Type: Case Report | First Published: June 02, 2016

Sedaghatian-type spondylometaphyseal dysplasia (SSMD) is a lethal neonatal form of spondylometaphyseal dysplasias that is reported rarely. The case of a female infant demonstrating a clinical phenotype consistent with a diagnosis of SSMD was presented. She died with acute evidence of myocardial injury. In SSMD, certain organ systems including the central nervous, cardiac, and skeletal systems, are clearly involved. Although the exact cause of the uniform fatality remains unclear, cardiac involve...

 Open Access DOI:10.23937/2378-3648/1410024

Susceptibility of Patients with Manganese Superoxide Dismutase Ala16val Genetic Polymorphism to Type 2 Diabetes Mellitus and its Complications in a Sample of Lebanese Population

Abir M Zahreddine, Mohamed E Moustafa and Hala A Chamieh

Article Type: Original Article | First Published: May 24, 2016

Oxidative stress has been frequently associated with the development of type 2 diabetes mellitus. Manganese superoxide dismutase (MnSOD) is one of the most important enzymes responsible for the defense against oxidative damage in the mitochondria. A polymorphism in the second exon of the MnSOD at position 16 that changes Ala into Val, induces changes in the structural conformation and mitochondrial transport of MnSOD. This polymorphism affects the scavenger activity of the enzyme and generates h...

 Open Access DOI:10.23937/2378-3648/1410023

A Perspective on the Algorithms Predicting and Evaluating the RNA Secondary Structure

Giulia Fiscon, Giulio Iannello and Paola Paci

Article Type: Review Article | First Published: May 20, 2016

Investigating the RNA structure contributes greatly to understand RNA roles in cellular processes. Indeed, functional RNAs show specific instrumental sub-structures for their interaction with other molecules. The RNA structure prediction will provide fundamental insights into developing hypothesis connecting function to structure, but it is a challenging and unsolved task yet. We aim at discussing the current status of the widespread RNA folding tools and comparing their performances on RNA fami...

 Open Access DOI:10.23937/2378-3001/3/3/1049

Effect of Elasticity on Flow Characteristics Inside Intracranial Aneurysms

Ryuhei Yamaguchi, Gaku Tanaka and Hao Liu

Article Type: Review Article | First Published: May 25, 2016

Many medical and bioengineering researchers have investigated flow behavior inside intracranial aneurysms using computational fluid dynamics. The majority of these studies assume to be rigid wall, but blood flows through a deformable elastic vessel. A few researchers have tried to simulate using fluid-structure interaction because an elastic wall implicates the decrease of wall shear stress inside the aneurysms. The current experimental model with the elastic wall has been carried out using part...

 Open Access DOI:10.23937/2378-3001/3/3/1048

Developmental Venous Anomaly Adjacent to Aqueduct of Sylvius

Kenichi Nishiyama and Akira Hasegawa

Article Type: Case Report | First Published: May 13, 2016

A 15-year-old boy presented to our hospital with headache after head trauma caused by a traffic accident. T2-weighted axial MR-images demonstrated the deep medullary veins of the cerebellum converging on the roof of the fourth ventricle. These veins drained into the subependymal vein, which then drained into the precentral cerebellar vein (Figure 1). MR-cisternography with 3D Fourier transformation constructive interference in steady state (CISS), which can depict the venous anatomy when it is s...

 Open Access DOI:10.23937/2572-4010.1510013

Association of Severe Obesity with the Metabolic Profile of Adolescents and Adults

Jessica Socas Teixeira, Aline Bull, Silvia Elaine Pereira, Carlos Saboya and Andrea Ramalho

Article Type: Original Article | First Published: May 30, 2016

Objective: To evaluate, in adolescents and adults, the association of severe obesity with the extent of the metabolic changes shown. Methods: This is an observational comparative study with a population consisting of adolescents with severe obesity and adults with class III obesity. The patients underwent anthropometric, biochemical and clinical evaluations. We evaluated the lipid profile (total cholesterol, LDL-c, HDL-c and triglycerides), C-reactive protein (CRP) and fasting glucose. Insulin s...

 Open Access DOI:10.23937/2572-4010.1510012

Mood Disorders and Bariatric Surgery Patients: Pre- and Post- Surgery Clinical Course- An Overview

Lucia Godini, Giovanni Castellini, Enrico Facchiano, Marcello Lucchese and Valdo Ricca

Article Type: Review Article | First Published: May 29, 2016

Aim: The purpose of the study was to evaluate the clinical course before and after bariatric surgery (BS) of patients affected by mood disorders as Major Depressive Disorder (MDD) and Bipolar Disorder (BD). Methods: A search in Pubmed's medline was performed for English-spoken articles published from January 2000 to May 2015 using the keywords 'depression', 'bipolar disorder', 'mood disorders' and 'antidepressive drugs' combined with 'bariatric surgery' and 'obesity surgery'. A total of 43 studi...