Open Access DOI:10.23937/2474-3690/1510018
Mineralocorticoid Receptor Blockade Lowers Blood Pressure and Improves Endothelial Function in Obese Patients with Metabolic Syndrome
Danielle GA Ezequiel, Frida Liane Plavnik, Monica B Costa, Julio CM Lovisi, Fernando AB Colugnati, Juliana Machado Saraiva and Rogerio B de Paula
Article Type: Original Article | First Published: October 17, 2016
Introduction: Aldosterone has been implicated in the pathophysiology of both metabolic syndrome (MS) and MS-associated arterial hypertension, despite the use of mineralocorticoid receptor antagonists in these scenarios has been little studied. Objectives: To assess the effects of mineralocorticoid blockade on blood pressure as well as metabolic and renal parameters in mild hypertensive subjects with MS compared with an active control group....
Open Access DOI:10.23937/2474-3690/1510017
Advances in Low-Dimensional Mathematical Modeling of the Human Cardiovascular System
S Malatos, A Raptis and M Xenos
Article Type: Review Article | First Published: September 22, 2016
The mathematical modeling of blood flow in the cardiovascular system has long history. Zero-dimensional (0D) and one-dimensional (1D) models contribute actively to the study of the human cardiovascular system. Usually, low-dimensional models consist of a system of time dependent equations that do not involve spatial derivatives, thus reducing the computational complexity compared to multi-dimensional models. Despite that more complex 3D cardiovascular models are available, there is a tendency of...
Open Access DOI:10.23937/2474-3690/1510016
MyHEART: A Non Randomized Feasibility Study of a Young Adult Hypertension Intervention
Heather M Johnson, Jamie N LaMantia, Ryan C Warner, Nancy Pandhi, Christie M Bartels, Maureen A Smith and Diane R Lauver
Article Type: Original Research | First Published: September 12, 2016
In the United States, young adults (18-39 year-olds) have the lowest hypertension control rates (35%) compared to middle-aged (58%) and older (54%) adults. Ambulatory care for hypertension management often focuses on medication with little time for self-management and behavioral counseling. This study was designed to evaluate the feasibility of MyHEART, a telephone-based health coach self-management intervention for young adults....
Open Access DOI:10.23937/2474-3690/1510015
Angiotensin-Converting Enzyme Inhibitor-Induced Cough Prevalence in Refractory Hypertensive Patients
Andre Nascimento Publio Pereira, Roque Aras Junior, Cristiano Ricardo Bastos Macedo, Ricardo Ribeiro do Nascimento Teixeira, Iuri Reseda Magalhaes, Diego Sant'ana Sondre, Bianca de Almeida Nunes and Juliana Queiroz Vasconcelos Muniz
Article Type: Original Article | First Published: August 18, 2016
Refractory Arterial Hypertension (RAH) is characterized by persistently high blood pressure values. Angiotensin Converting Enzyme (ACE) inhibitors in combination with other antihypertensive drugs are effective for RAH and have good clinical tolerance. According to the literature, the adverse effect of cough in patients using ACE inhibitors occurs in 5 to 20% of them. However, in clinical practice, the incidence appears to be higher, making it difficult the therapeutic adherence....
Open Access DOI:10.23937/2572-3243.1510025
Deep Venous Thrombosis in Behcet's Syndrome: Is Anticoagulation Necessary?
Nieves Marie Leonardo and Julian McNeil
Article Type: Case Report | First Published: October 22, 2016
Deep vein thrombosis (DVT) in the lower extremities is a common medical presentation. Anticoagulation is the cornerstone of management. However, not all DVTs require anticoagulation. We report a case of DVT in a patient with Behcet's Syndrome where venous inflammation is the primary pathology and anti-inflammatory therapy is primary and the role of anti-coagulation is moot....
Open Access DOI:10.23937/2572-3243.1510024
Effects of Seated Whole-Body Vibration Exposure on Cervical and Trunk Proprioception and Static and Dynamic Postural Stability
Takashi Nagai, Heather M Bansbach, Mallory S Faherty, John P Abt, Timothy C Sell and Scott M Lephart
Article Type: Research Article | First Published: October 05, 2016
Prolonged exposure to seated whole-body vibration (WBV) is considered a risk factor for neck pain (NP) and low back pain (LBP) in aircrew. Decreased trunk proprioception following WBV exposure has been previously reported. Proprioceptive feedback from the mechanoreceptors of the neck and trunk regions plays an important role in maintaining proper postural stability; therefore, it was hypothesized that WBV exposure would negatively affect both cervical/trunk proprioception and postural stability,...
Open Access DOI:10.23937/2572-3243.1510023
Phoenix Project for Improving the Quality of Life in Rheumatic Diseases: Preliminay Results
Middei Sonia, Pasqualucci Simona and Martin-Martin Luis Severino
Article Type: Research Article | First Published: October 03, 2016
Rheumatic chronic diseases (RCD) are among the most common chronic non-communicable diseases. They are the leading cause of disability in developed countries, and consume a large amount of health and social resources. The purpose of this preliminary study (PHOENIX PROJECT) was to evaluate changes in the quality of life of patients suffering from RCD followed by talks in Group Counseling for emotional support. Group Counseling talks for emotional support is a behavioural intervention to facilitat...
Open Access DOI:10.23937/2572-3243.1510022
Current Approaches in Myofunctional Orthodontics
Begum Gokce and Burcak Kaya
Article Type: Short Review | First Published: September 30, 2016
Functional matrix theory is the most widely accepted theory of craniofacial growth recently. Moss and Salentijn, have suggested that the craniofacial growth is the result of the changes in functional matrix. Accordingly, neither bone nor cartilage is responsible for the growth of the craniofacial skeleton. The growth of the face, is formed by the growth of the soft tissues as a result of functional requirements. The soft tissues grow; and bone and cartilage react....