Open Access DOI:10.23937/2572-3286.1510019
Interventional and Surgical Treatments for Renal Artery Aneurysms
Donghua Xie, Edward Gheiler and Xiangfei He
Article Type: Review Article | First Published: February 03, 2017
Renal artery aneurysm (RAA) is an infrequent entity. Most of them are asymptomatic, but when they present as a rupture a high mortality is associated. Due to the potential risks of rupture and renal dysfunction and some persistent symptoms like hypertension, RAAs must be treated if feasible. Coil embolization or covered stent placement can now be used to treat patients with aneurysms whose size or location would make a surgical approach problematic and patients in whom surgery is considered to p...
Open Access DOI:10.23937/2378-3516/1410064
Inhaler Technology
Gumani D, Newmarch William, Puopolo Angelica and Casserly Brian
Article Type: Review Article | First Published: December 12, 2016
Inhalers are a commonly used device to deliver medication to individuals with airway disease. With correct use, inhalers are very effective at providing quick and effective symptomatic relief within the lung, avoiding high levels of systemic exposure. These pharmacokinetic characteristics widen the therapeutic index, thus allowing for maximal therapeutic benefit with minimal adverse effects. However, this theoretical advantage is somewhat attenuated by incorrect use of the inhaler device....
Open Access DOI:10.23937/2469-584X/1510041
Trends in Inflammatory Bowel Disease- Comparison Between the Arab and Jewish Population in Israel
Benjaminov Fabiana, Stein Assaf, Segal Ramona, Konikoff Fred M, Naftali Timna and Hermoni Doron
Article Type: Research Article | First Published: January 19, 2017
Genetic and environmental factors have a major influence on the pathophysiology of inflammatory bowel disease (IBD). Older studies reported a very low prevalence of IBD among the Arab population in Israel. Evaluate the current prevalence and disease characteristics of IBD in the Israeli-Arab population and to compare them to the Jewish population in the same area....
Open Access DOI:10.23937/2469-5742/1510021
Ileus as First Sign of De Novo Neuroendocrine Prostate Cancer
Mads Ryo Jochumsen, Bjorn Agerbo Sahlholdt and Jorgen Bjerggaard Jensen
Article Type: Research Article | First Published: February 13, 2017
A 73-year-old man with almost no previous medical history was admitted acute with stomach pain, distended abdomen, stop of defecation and feculent vomiting. The patient had been constipated for three months and about a month before admission, a coloscopy was performed presenting no findings. Computed Tomography (CT) showed mechanical bowel obstruction and a huge malignantly transformed prostate gland as the triggering cause....
Open Access DOI:10.23937/2469-5742/1510020
New Insights into the Chemical and Isotopic Composition of Human-Body Biominerals. II: COM Kidney Stones from Greece
Dimitra Athanasiadou, Athanasios Godelitsas, Dimosthenis Sokaras, Andreas-Germanos Karydas, Elisavet Dotsika, Stelios Xanthos and Maria Gamaletsou
Article Type: Research Article | First Published: February 10, 2017
Kidney stone disease (urolithiasis) is a serious health problem, involving more than 5% of the population, especially in developing countries. Urolithiasis, the formation of urinary calculi in the kidney, bladder and/or urethra, can be attributed to several risk factors related to geographical region, gender and dietary habits....
Open Access DOI:10.23937/2572-3987.1510009
Levothyroxine for Hypothyroidism: Current Status of Biowaiver and Bioequivalence Studies
Nunez-Guzman NA, Munoz-Ibarra AI, Ruiz-Molina D, Figueroa-Nunez B and Garcia-Perez ME
Article Type: Review Article | First Published: January 24, 2017
Hypothyroidism is a common disease that needs to be closely treated, in order to reduce adverse symptoms and pathophysiological effects. For thyroid hormone replacement is preferred a therapy with a synthetic form of thyroxine (levothyroxine), a drug recognized by its Narrow Therapeutic Index. Generic levothyroxine can be an economic alternative for Hypothyroidism treatment....
Open Access DOI:10.23937/2572-407X.1510008
Adrenal Neuroblastoma Mimicking Pheochromocytoma in an Adult with Neurofibromatosis Type 1
Harbi Khalayleh, Hilla Knobler, Vitaly Medvedovsky, Edit Feldberg, Judith Diment, Lena Pinkas, Guennadi Kouniavsky and Taiba Zornitzki
Article Type: Case Report | First Published: February 21, 2017
A 42-year-old normotensive woman with neurofibromatosis type 1 (NF1) with typical cutaneous manifestations (multiple neurofibromas, cafe-au-lait spots and axillary freckling), underwent evaluation for abdominal pain and a large left adrenal mass displacing the spleen pancreas and colon, was found upon a CT scan....