Open Access DOI:10.23937/2474-3682/1510066

Magnetic Resonance Imaging Findings of Central Diabetes Insipidus in a Child

Serdar Arslan, Hasan Erdogan, Muhsin Nuh Aybay, Arzu Cengiz, Fatma Zeynep Arslan and Ismet Tolu

Article Type: Image | First Published: June 14, 2017

An 18-year-old male patient presented to our hospital with polyuria, polydipsia and nocturia. He reports drinking 4-5 gallons of water every day due to extreme thirst. Her laboratory tests revealed serum sodium in the range of 140-145 mEq/L, serum osmolality of 295 mOsm/kg, with a concomitant urine osmolality of 279 mOsm/kg....

 Open Access DOI:10.23937/2378-2951/1410098

Left Atrial Wall Thickness and Pulmonary Vein Size are Increased in Patients with Atrial Fibrillation Compared to Healthy Controls - A Multidetector Computed Tomography Study

Anna F Thomsen J Tobias Kuhl, Klaus F Kofoed, Andreas Fuchs, Patricia M Udholm, Jakob B Norsk, Xu Chen, Steen Pehrson, Borge G Nordestgaard, Lars Kober and Peter K Jacobsen

Article Type: Research Article | First Published: June 26, 2017

Atrial Fibrillation (AF) is the most common cardiac arrhythmia and a cause of increased morbidity and mortality. Left Atrial (LA) tissue characteristics play an important role in the pathogenesis of AF. Catheter ablation of AF has emerged as a popular treatment option, however predictors of treatment success are not clearly defined....

 Open Access DOI:10.23937/2378-2951/1410097

Long Term High-Fat Diet-Induced Modification of Vascular Wall and Perivascular Adipose Tissue-Mediated Oxidative Stress: Consequences for Endothelium-Independent Vascular Function in Rats

Caroline Sanchez, Vincent Achard, Michel Grino and Stephane Tanguy

Article Type: Research Article | First Published: June 24, 2017

Visceral obesity, a feature of the metabolic syndrome, is associated with metabolic and cardiovascular diseases. Our aim was to study the influence of increased fat intake, a major determinant of central obesity, on Smooth Muscle Cells (SMC) reactivity and its interaction with Perivascular Adipose Tissue (PVAT), which plays an important role in the local regulation of vascular function, with a special emphasis on oxidative stress....

 Open Access DOI:10.23937/2572-4045.1510031

Sustained In Vivo Perfusion of a Re-Endothelialized Tissue Engineered Porcine Liver

Shennen A Mao, Jaime M Glorioso, Faysal M Elgilani, Silvana B De Lorenzo, Michael C Deeds, Dominique Seetapun, Brian Perrault, Bruce P Amiot, Anisha Singh, Clara T Nicolas, Yujia Wang, E Heidi Cheek, Taofic Mounajjed, Allan B Dietz, Jeff J Ross and Scott L Nyberg

Article Type: Research Article | First Published: June 12, 2017

Liver transplantation remains the only definitive treatment for end-stage liver disease. With only 6000 donor livers available each year nationally, the need far exceeds the supply. Innovative cell-based therapies, such as hepatic tissue engineering, offer alternatives to supplement the limited supply of quality organs for transplantation....

 Open Access DOI:10.23937/2572-4045.1510030

Mycotic Aneurism in Renal Transplantation Associated to Persistent Leucopenia. Case Report and Review of the Literature

Lorena Noriega-Salas and Sinhue Escalona-Delgado

Article Type: Case Report | First Published: May 31, 2017

A 27-years-old female with end stage kidney disease, received a deceased donor kidney transplant, the induction immunosuppression consisted in polyclonal anti-lymphocyte therapy. The maintenance therapy included plus to the immunosuppressive drugs, valganciclovir as prophylaxis of CMV....

 Open Access DOI:10.23937/2572-4045.1510029

Strategies in Preventing Diabetes after Pancreatectomy Using Islet Auto- and Allo-Transplantation

Tori Tucker, Kevin Labadie, Christopher Kopan, Michael Alexander and Jonathan RT Lakey

Article Type: Research Article | First Published: May 15, 2017

Over the years, pancreatectomy has been the primary treatment for chronic pancreatitis. Since the 1970s, total pancreatectomy has been shown to be effective at relieving pain that was experienced due to chronic pancreatitis. However, total pancreatectomy alone has the significant side effect of post-surgical diabetes....

 Open Access DOI:10.23937/2474-3690/1510024

Preeclampsia: Pathophysiology and the Maternal-Fetal Risk

Gibran Khalil and Afshan Hameed

Article Type: Review Article | First Published: May 25, 2017

Preeclampsia complicates about 5% of all pregnancies worldwide and is one of the leading causes of maternal and fetal morbidity and even mortality. The disorder is specific to pregnancy characterized by new onset of hypertension and end-organ dysfunction including proteinuria after 20 weeks of gestation....

 Open Access DOI:10.23937/2469-5718/1510060

Cumulative Effects of Occupational Loading as a Risk Factor for Hip Pain in UK Military Personnel - Study Protocol of a Case Control Study

Russell J Coppack, James L Bilzon, Andrew K Wills, Ian M McCurdie, Daniel T Walton, Alastair M Nicol and Alexander N Bennett

Article Type: Study Protocol | First Published: June 12, 2017

High rates of hip Osteoarthritis (OA) have been reported in occupational sub-groups exposed to prolonged and strenuous physical activity levels. The military population is particularly at risk given the demands inherent to this population....

 Open Access DOI:10.23937/2572-4037.1510018

Dread According to Kierkegaard

Mark H Stone

Article Type: Review Article | First Published: May 20, 2017

An explication of Kierkegaard's concept of dread provides insight into the life and mind of one of the first existentialists noted for giving particular attention to the subjective individual. His view of dread shows it to be much deeper and more complex than anxiety by invoking an awesome expanse of freedom and possibility....

 Open Access DOI:10.23937/2469-5734/1510042

Treatment Experiences of Individuals Born with Cleft Lip and/or Palate in the UK

Aidan Searle, Shabnum Ali, Scott Deacon and Andrea Waylen

Article Type: Case Report | First Published: May 15, 2017

Despite receiving treatment by specialist services in childhood and adolescence some individuals report ongoing cleft-related issues that impact on their self-confidence and quality of life due to both aesthetic and functional reasons....