Open Access DOI:10.23937/2469-5742/1510046
Br, Fe, Rb, Sr, and Zn Levels in the Prostatic Secretion of Patients with Chronic Prostatitis
Vladimir Zaichick and Sofia Zaichick
Article Type: Research Article | First Published: October 12, 2018
Chronic prostatitis (CP) is an internationally important health problem of the man, particularly in developed countries. The aim of this exploratory study was to evaluate whether significant changes in the levels of Zn and some other trace elements of prostatic fluid exist in the inflamed prostate. Prostatic fluid levels of Br, Fe, Rb, Sr, and Zn were prospectively evaluated in 33 patients with CP and 42 healthy male inhabitants. Measurements were performed using 109Cd radionuclide-induced energ...
Open Access DOI:10.23937/2469-5742/1510045
Penile Cancer: Case Report
Mehmet Solakhan and Ersan Bulut
Article Type: Case Report | First Published: October 11, 2018
Penile cancer is the most rarely observed cancer among male urogenital system tumors and is observed at an annual rate of 1/100000. Penile cancer risk increases significantly with increasing age, poor hygiene, and the presence of a foreskin. The most frequently observed type is the squamous cell carcinoma (SCC). Clinical examination of the inguinal lymph nodes is critical, as nodal involvement is a poor prognostic feature. Patients with T2 or higher-grade tumors and lymphovascular invasion are a...
Open Access DOI:10.23937/2469-5742/1510044
Case of Penile Malignant Peripheral Nerve Sheath Tumor in a Twenty-Year-Old Male with Neurofibromatosis Type 1
Orchid Djahangirian, Ngoc-Anh Tran, Lilibeth Torno and Antoine Khoury
Article Type: Case Report | First Published: October 11, 2018
The patient's past medical history was significant for juvenile myelomonocytic leukemia (JMML) that was treated at the age of three years with chemotherapy, total body irradiation and splenectomy and bone marrow transplantation. The patient was clinically diagnosed with NF1 on the basis of multiple café au lait macules, cutaneous neurofibromas, and axillary and inguinal freckling. At the age of 19 years, imaging performed to evaluate a two-week history of coughing revealed a right paratracheal ...
Open Access DOI:10.23937/2378-3664.1410024
Silver Nanoparticles - Green Synthesis with Aq. Extract of Stems Ipomoea Pes-Caprae, Characterization, Antimicrobial and Anti-Cancer Potential
Subha Veeramani, Ernest Ravindran RS, Preethi Ramadoss, Cyrril Joseph, Kirubanandan Shanmugam and Renganathan S
Article Type: Research Article | First Published: October 10, 2018
Green synthesis is a novel process for the preparation of numerous metallic nanoparticle and provides a safer and eco-friendly process simultaneously achieving functionalization of nanoparticles with bioactive molecules in the plants extract. Green synthesis of silver nanoparticles (AgNPs) is performed using the aqueous extract of Ipomoea pes-caprae stems which acts as a bio-reducing agent. UV spectroscopic investigation confirms the formation of AgNPs by noticing the peak at 448 nm due to its s...
Open Access DOI:10.23937/2378-3664/1410023
In Vitro Dissolution Studies on Naproxen-PVP Nanoformulations Show Enhanced Oral Bioavailability of Naproxen
Sandeep Patnaik, Aditya D Kurdekar, LA Avinash Chunduri, C Prathibha and K Venkataramaniah
Article Type: Research Article | First Published: October 08, 2018
Phase solubility behavior, physico-chemical characteristics, cytotoxicity, morphology and dissolution enhancement of Naproxen-PVP Nanoformulations have been studied. Drug-polymer ratios of 1:1, 1:2, 1:3, 1:4 for the poorly water-soluble drug, naproxen and the polymer PVP are prepared via wet milling using a conventional Retsch Planetary ball mill. The highest dissolution enhancement over that of the pure drug, 310% was achieved for the formulation ratio of 1:4. This ability of amphiphilic surfac...
Open Access DOI:10.23937/2474-3674/1510046
Early Protocolized Bedside Ultrasound in Shock: Renal Function Improvements and Other Lessons Learned
Talayeh Rezayat, Igor Barjaktarevic, Ian Mecham, Lisa Yee, Ramy Salah, Lisa Zhu, Kereat Grewal, Jody Anderson, Nicholas J Jackson, David Elashoff and Elizabeth Turner
Article Type: Research Article | First Published: October 06, 2018
Rapid assessment and treatment of the critically ill in shock is crucial to survival. The RUSH (Rapid Ultrasound in Shock and Hypotension) exam uses Ultrasound (US) to determine the etiology of undifferentiated shock, but data to demonstrate impact of focused US on clinical outcomes is sparse. This study aimed to assess the clinical impact of early incorporation of the RUSH US exam in the care of patients with new onset shock on a population level....
Open Access DOI:10.23937/2377-4630/1410074
Accidental Perforation of Subarachnoid Space with Spinal Introducer
Luiz Eduardo Imbelloni and Micaela Barbosa L Sales
Article Type: Case Report | First Published: October 17, 2018
The existence of fine gauge needles with a traumatic bevel, pencil tip type; it is possible to increase the indication of spinal anesthesia in young people and to reduce the incidence of post-puncture headache. We present a case of a post-dural puncture headache occurring after perforation dura mater using a 20-gauge needle introducer for spinal anesthesia with Whitacre needle....