Open Access DOI:10.23937/2474-3674/1510056
A Young Woman with Dyspnea Following Delivery- Cardiomyopathy, Pulmonary Embolism or Both?
Yonatan Gershinsky, David Leibowitz and Shaden Salameh
Article Type: Case Report | Publication Updated: November 21, 2018
Postpartum cardiomyopathy is an important cause of heart failure in young women with an increasing rate in recent years. It may occur from the last month of pregnancy and up to five months after delivery. The etiology remains unclear and the disease has a high level of morbidity and mortality. Complications include CHF, arrhythmias, cardiogenic shock and thromboembolism. Treatment is similar to the treatment for CHF. Bromocriptine has shown encouraging preliminary results but is not standard the...
Open Access DOI:10.23937/2474-3674/1510055
Role of Obstetric High Dependency and Intensive Care Unit in Improving Pregnancy Outcome and Reducing Maternal Mortality-A Study in Rural Central India
Surekha Tayade, Neha Gangane, Poonam Shivkumar, Dinesh Baswal, Apurva Ratnu, Himanshu Bhushan and Jaya Kore
Article Type: Research Article | Publication Updated: November 19, 2018
To analyze the requirement of High Dependency Unit (HDU) and Intensive care Unit (ICU) in an obstetric population in terms of utilization rate, indications for admission, interventions required and gestational outcome. Retrospective observational study was carried out from October 2016 to September 2017 in Kasturba Hospital, Mother and Child Health Wing, Mahatma Gandhi Institute of Medical Sciences Sewagram placed in rural central India. Data related to indications for HDU/ICU admission, interve...
Open Access DOI:10.23937/2469-5823/1510107
Qualitative Study of Supervisor Feedback on Nurse Managers' Reflective Journals
Yumiko Kuraoka
Article Type: Original Article | Publication Updated: November 17, 2018
A total of 63 nurse managers participated in an experiential learning-based program that included writing entries in a reflective journal and supervisor feedback. The Experiential Learning Inventory on the Job (ELI) was administered before and after the program. Overall, 10 nurse managers showed apparent changes in their Experiential Learning Inventory scores after completing the program. We qualitatively analyzed the data from 41 reflective journal entries written by these 10 nurses along with ...
Open Access DOI:10.23937/2378-3656/1410242
Efficacy and Safety of GLP-1 Agonists in Chronic Kidney Disease: A Case Series
Awdishu L and Morello CM
Article Type: Case Series | Publication Updated: November 17, 2018
Tight glycemic control has been demonstrated to reduce the incidence of microvascular complications in type 1 and 2 diabetes. However, tight control comes at a risk of hypoglycemia, which is further increased in advanced diabetic kidney disease. GLP-1 agonists significantly lower HgA1c and have added benefits of early satiety and weight loss. However, the safety and efficacy of these agents has not been well documented in CKD stage 3-4....
Open Access DOI:10.23937/2469-5734/1510071
Successful Treatment of Persistent Bleeding from Gingival Ulcers in an Adolescent Patient with Irsogladine Maleate
Atsushi Masui, Yoshihiro Morita, Takaki Iwagami, Masakazu Hamada, Hidetaka Shimizu and Yoshiaki Yura
Article Type: Case Report | Publication Updated: November 17, 2018
Gingival ulcer is often accompanied by severe pain and bleeding and prevents the practicing of appropriate oral hygiene. Most inflammatory and immune-mediated gingival ulcers can be successfully treated with topical corticosteroids, but those refractory to corticosteroids are difficult to treat. An 18-year-old female visited our clinic with a complaint of gingival bleeding. Since topical corticosteroids and oral antibiotic were not effective for gingival ulcers of the patient, an anti-gastric ul...
Open Access DOI:10.23937/2474-3674/1510054
Regional Citrate Anticoagulation in Continuous Renal Replacement Therapies
Domingo Daga-Ruiz, Jonathan Pérez-Vacas, Fernando Segura-Gonzalez, Gonzalo Moratalla-Cecilia, Araceli Puerto-Morlan, Pilar Nuevo-Ortega and Alba Fernandez-Porcel
Article Type: Original Article | Publication Updated: November 16, 2018
We designed this Observational prospective cohort study to assess the safety, effectiveness and efficiency of the introduction of Regional Citrate Anticoagulation (RCA) as election strategy for Continuous Renal Replacement Therapies (CRRT). All patients in need of CRRT without contraindications to the use of RCA were included. It was necessary to adapt and implement the original RCA protocol, for the first time in a Spanish ICU. A total of 90 patients between October 2016 and October 2017 were i...
Open Access DOI:10.23937/2469-5777/1510065
A Pharmacokinetic Analysis of Continuously Infused Piperacillin/Tazobactam in Critically Ill Trauma Patients
Kevin M Silinskie, Bradley D Domonoske and Christine S Cocanour
Article Type: Research Article | Publication Updated: November 16, 2018
To define the serum pharmacokinetics of a fixed-dose of piperacillin/tazobactam at 24, 48, and 72 hours of therapy when administered as a continuous infusion in critically ill trauma patients. Although we found a wide variability in serum piperacillin/tazobactam concentrations, the administration of a 16/2 g per day dose as a continuous infusion achieves optimal pharmacokinetic parameters for commonly isolated microorganisms in critically ill trauma patients....
Open Access DOI:10.23937/2469-5734/1510070
Conservative Treatment of Primary and Nonsyndromic Odontogenic Keratocyst: An Overview of the Practice
Yuri Slusarenko da Silva and Maria da Graca Naclerio-Homem
Article Type: Research Article | Publication Updated: November 16, 2018
Odontogenic Keratocyst (OKC) is a locally aggressive odontogenic cyst with a high recurrence rate after treatment. Several conservative surgeries have been suggested in the treatment of Keratocysts but working with an overview of the practice may render better outcomes. We conducted a literature review in the databases MEDLINE, Web of Science, Scopus, Cochrane Library and Google Scholar as well as in the gray literature (books and thesis) for studies reporting on the pathogenesis, clinical prese...
Open Access DOI:10.23937/2378-3656/1410241
Hyponatraemia Workup Leading to a Diagnosis of Primary Empty Sella Syndrome: A Case Report
Guillermo Ropero Luis, Sonia Santamaria Fernandez, Jesica Martín Carmona and Ricardo Gomez Huelgas
Article Type: Case Report | Publication Updated: November 16, 2018
A 61-year-old woman was admitted to our ward - after her third visit to the Emergency Department in two months - because of progressive lethargy, weakness, and persistent euvolaemic hyponatraemia. Based on the results of the first diagnostic workup (complete blood count, serum and urinary biochemistry), a diagnosis of Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) was established. A comprehensive second diagnostic workup was performed, leading to the diagnosis of anterior hypop...