Open Access DOI:10.23937/2378-2951/1410130
Carotid Sinus Syndrome in a Patient with Symptomatic Abdominal Aortic Aneurysm - A Case Report
Ksenija Stevanovic, Ranko Trailovic, Biljana Kukic, Marko Dragas, Slobodan Cvetkovic and Lazar Davidovic
Article Type: Case Report | First Published: November 12, 2018
Carotid sinus syndrome (CSS) is defined as syncope with reproduction of symptoms during 10s of carotid sinus massage. The etiology of this condition is unknown, patients are usually symptomatic and present with episodes of syncope. Due to the associated marked sinus bradycardia, sinus arrest or severe hypotension, carotid sinus syndrome may be life-threatening. In patients without previous symptoms, CSS must be promptly recognized and treated, otherwise may lead to catastrophic consequences. If ...
Open Access DOI:10.23937/2572-3243.1510059
Biologics for Osteoporosis: Where Do We Stand?
Tamer A Gheita and Hanan M Fathi
Article Type: Editorial | First Published: November 12, 2018
Osteoporosis is a common disease with wide prevalence, especially in seniors. Fractures induced by osteoporosis not only decrease the patient's quality of life, but also cause heavy financial burden to the society during medical treatment making this major metabolic bone disease a growing health-economic problem worldwide. Estimated annual costs for osteoporotic fractures are between $10 billion and $17 billion in the United States with a provisional estimation by year 2025 to rise up to $25.3. ...
Open Access DOI:10.23937/ijor-2017/1710009
Pembrolizumab Monotherapy in Relapsed Hepatocellular Carcinoma Post Living Donor Liver Transplantation and Sorafenib
Fadi Nasr, Ahmad Al Ghoche, Saada Diab, Janah Maddah, Layal Mansour, Ali kassem and Abd El Karim Gheith
Article Type: Case Report | First Published: November 12, 2018
Despite of the high incidence of hepatocellular carcinoma (HCC), treatment strategies stays restrained. New treatment aspects remain a necessity to improve overall survival of patients. Here, we report for the first time a 2 years complete remission of hepatocellular carcinoma with pembrolizumab after failure of sorafenib and progression after liver transplantation. Immunotherapy became a field of interest in HCC for researchers and clinicians in order to establish new immunotherapy modalities t...
Open Access DOI:10.23937/2378-346X/1410096
Low Vision Aid for a Patient with the Optic Neuropathy Due to Neuro-Brucellosis
Fatih M Adibelli and Deniz Altinbay
Article Type: Case Report | First Published: November 10, 2018
Brucellosis is a multisystem infectious disease, which still endemic in Middle East, Mediterranean and South America. Bilateral optic neuritis secondary to the meningeal inflammation is very rare complication of brucellosis. Here we present a 13-year-old male patient with the ocular brucellosis who has optic neuropathy, concluded his treatment and low vision aid for the visual impairment. Brucellosis is a multisystem infectious disease, which appear in miscellaneous clinical manifestation. Vario...
Open Access DOI:10.23937/2572-3235.1510040
Tensor Voting Based Vascular Bifurcation Detection in CT Images of Lung
Ruifang Sun, Jingli Shi and Xuan Yang
Article Type: Research Article | First Published: November 08, 2018
The accurate detection of vascular bifurcations is not helpful for pulmonary vascular disease diagnosis, but vital in (Computed Tomography) CT image analysis and processing of lung. We propose a tensor voting based method for vascular bifurcation detection in CT image of lung, which a vessel enhancement method is firstly proceeding to initially extract vessel structure, on which we perform ball voting with the pixels. Then counting the number of votes of each pixel and calculating the local maxi...
Open Access DOI:10.23937/2378-2951/1410128
Neurologic and Renal Outcomes of Elective Proximal Aortic Repair and Current Cannulation Trends
Sahin Iscan and Bortecin Eygi
Article Type: Research Article | First Published: November 07, 2018
Cerebral protection is a big technical difficulty for aortic surgery. Increased use of antegrade cerebral perfusion (ACP) and deep hypotermic circulatory arrest in experienced hands made open surgery of the ascending aorta and aortic arch aneurysms more successful today. The increase in the variety of surgical equipment to provide unilateral and bilateral cerebral perfusion or monitorization, the effectiveness of the cerebral protection instantly decreased the risk of perioperative stroke or pos...
Open Access DOI:10.23937/2378-2951/1410127
Measurement of the QT Interval: Lessons from Thirty-Two Animal Species for the Correction of the QT Interval by Heart Rate
Simon W Rabkin
Article Type: Review Article | First Published: November 07, 2018
The optimal method to correct the QT interval, an important indication of arrhythmia risk, for the impact of heart rate has been controversial. The fundamental biologic relationship of the QT interval-heart rate relationship has rarely been studied across different species. The literature on the QT and heart rate of 32 different species was examined specifically in the whales, dolphins, Asian elephants, rhinoceros, camels, brown bears, grizzly bear, lions, tigers, sea lions, seals, donkeys, poni...
Open Access DOI:10.23937/2572-3278.1510028
Assessing Iodine Status in Frontline Healthcare
Ciara Wright and Heather Leeson
Article Type: Case Report | First Published: November 07, 2018
Iodine is essential for the synthesis of thyroid hormones and both hypothyroidism and iodine deficiency are prevalent worldwide. Assessing iodine status in the individual is difficult. Spot urine iodine measurement, while readily available, is not accurate. However, combining the clinical picture with a brief dietary history along with this simple measurement may give further insight into the likely iodine requirements of an individual. Supporting nutritional deficiency in subclinical hypothyroi...