Open Access DOI:10.23937/2474-3674/1510053
Intravenous Subdissociative-Dose Ketamine versus Morphine for Acute Traumatic Pain in Geriatric Patients in the Emergency Department: A Case Series
Sergey Motov, Jefferson Drapkin, Antonios Likourezos, Peter Flom, Catsim Fassassi, John Marshall and Ronald Simon
Article Type: Case series | First Published: November 12, 2018
We compare analgesic efficacy and safety of sub-dissociative dose ketamine (SDK) to morphine for managing acute traumatic pain in geriatric emergency department (ED) patients. A subset of geriatric patients from a randomized double-blind trail experiencing moderate to severe acute traumatic pain who received SDK at 0.3 mg/kg or morphine at 0.1 mg/kg by short intravenous infusion over 15 minutes was analyzed at 15, 30, 60, 90, and 120 minutes post-medication administration. Primary outcome was re...
Open Access DOI:10.23937/2469-5807/1510080
Intratubular Large Cell Hyalinizing Sertoli Cell Tumor of the Testes in Peutz-Jeghers Syndrome: A Case Report
Esra Polat, Yasemin Ozluk and Cagla Karaoglan
Article Type: Research Article | First Published: November 12, 2018
Polyposis disorders of the bowel in the pediatric population are associated with elevated risks of various cancers. The most common sites of the malignancies were the gastrointestinal system, breast, gynecological organs, testis, pancreas and lung. Testicular lesions are often overlooked as PJS predominantly appear in females. A 9-year-old boy was presented to gastroenterology policlinic due to pallor. He had a history of diagnostic laparotomy when he was nine dues to acute abdomen where intussu...
Open Access DOI:10.23937/iaos-2017/1710004
Optimizing the Anatomic Reduction of Complex Acetabular Fractures: A Technical Enhancement to the Modified Stoppa Approach
J Diranzo Garcia, L Hernandez Ferrando, V Estrems Diaz, V Zarzuela Sanchez, L Castillo Ruiperez, A Vilatela Gomez and A Bru Pomer
Article Type: Technical | First Published: November 12, 2018
In spite of the large variety of different techniques available for their treatment, acetabular fractures still pose a formidable challenge to the orthopedic surgeon, with a close relationship having been observed between degree of reduction, radiological findings and clinical results. The purpose of this manuscript is to introduce a technical enhancement that can be resorted to following exposure of the acetabular dome when using a modified Stoppa approach to facilitate reduction of bone fragme...
Open Access DOI:10.23937/iaoms-2017/1710012
Enucleation of Ameloblastoma - Case Report of 16-Year-Old Male
Anusha A Hennedige, Dimitrios Doumpiotis and Syed Ahad
Article Type: Case Report | First Published: November 12, 2018
Ameloblastomas are benign, locally invasive, polymorphic neoplasms that consist of proliferating odontogenic epithelium (usually of a follicular or plexiform pattern) lying in a fibrous stroma. They are known to have a high recurrence rate and are sometimes managed aggressively with radical surgery which usually involves wide resections and free flap reconstruction. Here we present a case report illustrating that certain variants of ameloblastomas have less likelihood of recurrence hence conserv...
Open Access DOI:10.23937/2378-346X/1410097
Are the Macular and Choroidal Thicknesses Exchange by the Management of Gyrate Atrophy?
Fatih M Adibelli and Halit Oguz
Article Type: Case Report | First Published: November 10, 2018
This is a case report of an 11-year-old boy complaining with deteriorated vision and with multiple peripheral lesions in his fundus in the setting of gyrate atrophy. Spectral domain optical coherence tomography showed, cystoid macular edema was in his both eyes. Plasma ornithine level was found elevated. According to these data, the patients were diagnosed with gyrate atrophy of the choroid and retina. The patient treated with vitamin B6 (pyridoxine) and an arginine-restricted diet....
Open Access DOI:10.23937/2469-5866/1410024
Neuregulin in Health and Disease
Juan Carlos Cespedes, Mingli Liu, Adriana Harbuzariu, Annette Nti, John Onyekaba, Hanna Watson Cespedes, Praveen K Bharti, Wesley Solomon, Precious Anyaoha, Sri Krishna, Andrew Adjei, Felix Botchway, Byron Ford and Jonathan K Stiles
Article Type: Review Article | First Published: November 10, 2018
Neuregulins, a family of EGF-like signaling molecules, are involved in cell-cell crosstalk and play an important role in development, maintenance and repair of the nervous system, heart, breast and other organs. Independent studies described a ligand for the oncogene ErbB2 (neu, Her2) and factors that stimulated proliferation of Schwann cells, as well as synthesis of receptors for acetylcholine by muscle. These ligands and factors are essentially products of the same gene, referred to by Marchio...
Open Access DOI:10.23937/ncr-2017/1710005
Frazier Suction Cannula Fluid Control Technical Note
Manuel Dujovny, Channan Kositzke, Pablo Sosa and Fabian Cremaschi
Article Type: Research Article | First Published: November 10, 2018
Suction capability in neurosurgery is a critical tool utilized to clear the field and improve visualization of anatomical structures. It is also used for fragmentation and debulking of pathological tumor masses. Prior to the Frazier cannula, there was no orifice bent pressure relief valve associated with suction; this tool provides independent dual suction force. The Frazier cannula has the capability to reach absolute suction or zero suction instantaneously. In this article, we introduce a new ...
Open Access DOI:10.23937/2469-5823/1510104
Training of French Nursing Students on Drawing Blood Culture: Results from a Broad Electronic Survey
Barbara Alves and Romain Jouffroy
Article Type: Original Article | First Published: November 08, 2018
Early implementation of appropriate treatments reduces mortality of sepsis, but before starting antibiotherapy, drawing blood culture is essential to identify the source of sepsis and to adapt treatment. Suboptimal practices result in blood culture contamination from patient's skin at the venepuncture site. As blood culture is the standard method to diagnose a bacteraemia, appropriate training of nursing students can promote good clinical practice. This study aims to evaluate the teaching and th...
Open Access DOI:10.23937/2572-4193.1510051
Hearing Threshold Level among Adult Diabetics in South-Western Nigeria
Omoregie J Idugboe, Babatope A Kolawole and Ebidisemene L Totyen
Article Type: Research Article | First Published: November 03, 2018
Among the most common chronic disorders of modern time, diabetes mellitus remains unique because of its multifactorial ramifications. Apart from the well-described association between congenital deafness and maternally inherited type of diabetes mellitus, the relationship between type 2 diabetes and hearing loss has been the subject of debate since Jordao reported a case of hearing loss with incipient diabetes coma almost 150 years ago. Documentation of this relationship among adult diabetics in...