Open Access DOI:10.23937/2378-2951/1410142

Long-Term Clinical and Echocardiographic Outcome in Patients with CRT and Functional Mitral Regurgitation: MitraClip versus Optimal Medical Therapy

Arianna Cirasa, MD, Antonio Popolo Rubbio, MD, Paolo Zappulla, MD, Angelo Di Grazia, MD, Daniela Dugo, MD, Salvatore Scandura, MD, Sarah Mangiafico, MD, Carmelo Grasso, MD, Corrado Tamburino, MD, PhD, Davide Capodanno, MD, PhD and Valeria Calvi, MD, PhD

Article Type: Research Article | First Published: April 03, 2019

This study sought to evaluate the clinical outcome in cardiac resynchronization therapy (CRT) patients with residual moderate-to-severe functional mitral regurgitation (FMR) who underwent percutaneous treatment with the Mitraclip System or were managed with medical therapy alone. Significant FMR can persist in 20-25% of patients after CRT and its management can be a challenge, due to the advanced heart failure (HF) and a variety of concomitant comorbidities. From a single center, two different g...

 Open Access DOI:10.23937/2572-3308.1510038

The Burden of Allergic Rhinitis and Impact of GRAZAX Grass Allergy Immunotherapy Treatment on Quality of Life in Germany and The Netherlands: Results from A Qualitative Study

Germain N, Gerth van Wijk R, Aballea S, Abetz-Webb L, Domdey A, Romano M and Toumi M

Article Type: Research Article | First Published: April 03, 2019

Allergic rhinitis is a major chronic respiratory disease that affects between 10% and 30% of adults and up to 40% of children globally. The purpose of this study was to understand the impact of allergic rhinitis and subsequent GRAZAX grass allergy immunotherapy (AIT) treatment on adults' and adolescents' quality of life. Clinicians treating allergic rhinitis in the Netherlands and Germany recruited adults and adolescents who had received at least 3 years of GRAZAX® treatment. Telephone intervie...

 Open Access DOI:10.23937/2572-3243.1510066

Total Talar Extrusion with Medial Malleolar Fracture

Rajesh MB, Chamma R and Ranganathan A

Article Type: Case Report | First Published: March 30, 2019

Total extrusion of the talus with disruption of all the ligaments is called "missing talus". It is a rare injury, associated with severe soft tissue damage and/or fracture. It is a tri-articular dislocation involving talotibial dislocation from above, subtalar joint below and talonavicular joint anteriorly. We present a report of a patient treated with immediate reimplantation and K-wire stabilisation leading to a successful outcome. A 57-year-old tourist had a closed anterolateral extrusion of ...

 Open Access DOI:10.23937/2469-567X/1510052

Multi-Center Study on the Prevalence of Human Immunodeficiency Virus/Herpes Simplex Virus Type-2 Co-Infection among Pregnant Women in Nigeria

Olayemi MATTHEW, Teclaire NDOMB, Joseph ONAKEWHOR, Bitrus MATAWAL, Esosa OSAGIE, Alashle ABIMIKU and Man CHARURAT

Article Type: Original Article | First Published: March 30, 2019

Substantial proportions of new HIV infections in sub-Saharan Africa are associated with herpes simplex virus type 2 (HSV-2) infection hence the magnitude of infection in the population suggests the expected course of HIV epidemic. We determined prevalence of genital herpes as a result of HSV-2 and its associated factors among pregnant women in Nigeria. A total of 2,362 sera of pregnant women aged 18-49 years attending two different antenatal clinics in two communities in Nigeria were analysed us...

 Open Access DOI:10.23937/2469-5718/1510124

Performance-Determining Coordinative and Conditional Abilities in the Fire Brigade Sport Discipline

Sophia Lichan, Robert Prill and Sven Michel

Article Type: Research Article | First Published: March 30, 2019

Fire brigade sport is a common sport in parts of Europe, with a growing body of popularity. In sports science, no research has been carried out in this field up to date. In consequence, there are no structures for talent scouting in firefighting sports. "100 m obstacle course" is one out of the four disciplines in this sport. For an efficient scouting of talents and training in general the necessary conditional and coordinative abilities must be identified. Dynamic balance, short sprint and moto...

 Open Access DOI:10.23937/2469-5718/1510123

The Association between Dietary Protein Intake Frequency, Amount, and State of Energy Balance on Body Composition in a Women's Collegiate Soccer Team

Ashley Delk-Licata, Christian E Behrens, Dan Benardot, Brenda M Bertrand, Paula C Chandler-Laney, Jose R Fernandez and Eric P Plaisance

Article Type: Research Article | First Published: March 30, 2019

Although protein consumption has been documented to influence body composition in humans, the effect on fat-free mass and fat mass, as influenced by the timing, frequency, and state of energy balance during the day when protein is consumed has not been fully investigated. The purpose of this cross-sectional study was to assess whether the amount and frequency of dietary protein intake, and the state of energy balance when consumed, are associated with body composition of collegiate women's socce...

 Open Access DOI:10.23937/2474-3674/1510071

The Quantum Entanglement Dynamics Induced by Non-Linear Interaction between a Moving Nano Molecule and a Two-Mode Field with Two-Photon Transitions Using Reduced Von Neumann Entropy and Jaynes-Cummings Model for Human Cancer Cells, Tissues and Tumors Diagnosis

Alireza Heidari, Jennifer Esposito and Angela Caissutti

Article Type: Research Article | First Published: March 30, 2019

In the current study, an analytical model is presented to analyze interaction between a moving 6-Methoxy-8-[[6-Methoxy-8-[[6-Methoxy-2-Methyl-1-(2-Methylpropyl)-3,4-Dihydro-1H-Isoquinolin-7-yl]Oxy]-2-Methyl-1-(2-Methylpropyl)-3,4-Dihydro-1H-Isoquinolin-7-yl]Oxy]-2-Methyl-1-(2-Methylpropyl)-3,4-Dihydro-1H Isoquinolin-7-ol and a two-mode field in the presence of two-photon transitions and in the coupling regime dependent on intensity for human cancer cells, tissues and tumors diagnosis. After iden...

 Open Access DOI:10.23937/2378-3656/1410261

Efficacy and Tolerability of the Nasal Airway Stent in the Treatment of Snoring

Takao Miyoshi, MSc, Ikumi Sasaki, MT, Fumika Koike, MSc, Saki Oyama, MT, Wakaba Furuie, MT, Miho Akaza, MD, PhD, Tetsuo Sasano, MD, PhD, Meiyo Tamaoka, MD, PhD, Yasunari Miyazaki, MD, PhD, Naohiko Inase, MD, PhD and Yuki Sumi, MD, PhD

Article Type: Brief Report | First Published: March 30, 2019

The nastent classic, a nasal airway stent (NAS), is a tube-shaped medical device that is positioned from the nose to the soft palate near the uvula. It is expected to reduce snoring by preventing the narrowing and obstruction of the airway and reduce apnea/hypopnea index (AHI) in patients with obstructive sleep apnea (OSA). Out of 23 subjects recruited, 18 completed the study. Most of the subjects showed improvements of snoring measured as the percentage of snoring time in their total sleep time...

 Open Access DOI:10.23937/2469-5807/1510085

Clinical and Genetics Findings in Mobius Syndrome: Role of Hoxa1 and Hoxb1 Mutations

Lineu Perrone Jr, Felipe Perozzo Daltoe, Luiz Carlos Areas Araujo, Fabio Daumas Nunes, Marina Helena Cury Gallottini and Andrea Mantesso

Article Type: Original Article | First Published: January 14, 2019

Mobius syndrome (MBS) is a rare congenital neurological disorder typically characterized by the absence or underdevelopment of the 6th and 7th cranial nerves, causing a loss of facial expression and strabismus. Other cranial nerves may be affected in addition to other structures such as the jaw, limbs, and anterior chest. While the primary cause of MBS has not yet been identified different hypotheses have been enumerated, including a possible genetic alteration. The Hoxb1 gene may be a good cand...

 Open Access DOI:10.23937/2469-5858/1510067

Combined Spinal Epidural Anesthesia in a Geriatric Patient Undergoing Hartmann Colostmy

Atilla Tutak, oznur Uludag, M Bahattin Pektas, Recai Kaya, Mevlut Dogukan, Ayse sahin Tutak

Article Type: Case Report | First Published: April 04, 2019

Geriatric age group; Increased sensitivity to anesthetic drugs, respiratory, general anesthesia due to cardiac complicatioans and cognitive dysfunction in the postoperative period is restricted. Combined spinal epidural anesthesia compared to general anesthesia and cardiac and respiratory stabilization, the extension of the duration of anesthesia, rapid mobilization, postoperative pain control, the advantages of early discharge and a reduction in costs. High doses of spinal or epidural anesthesi...